The p53/p21WAF/CIP pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency

Antioxidants and Redox Signaling

Volumn 14, Issue 6, 2011, Pages 985-997

  Westin, Erik R ^a   Aykin Burns, Nukhet ^b   Buckingham, Erin M ^a   Spitz, Douglas R ^b   Goldman, Frederick D ^c   Klingelhutz, Aloysius J ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; GLUTATHIONE DISULFIDE; PROTEIN P53; SUPEROXIDE; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DYSKERATOSIS CONGENITA; ENZYME ACTIVATION; ENZYME ACTIVITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; MITOCHONDRION; OXIDATIVE STRESS; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENESCENCE; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; TELOMERE;

BLOTTING, WESTERN; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DYSKERATOSIS CONGENITA; GLUTATHIONE; GLUTATHIONE DISULFIDE; HUMANS; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TELOMERASE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79951905790     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2010.3444     Document Type: Article

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