Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts

Aging Cell

Volumn 6, Issue 3, 2007, Pages 383-394

  Westin, Erik R ^a   Chavez, Elizabeth ^b   Lee, Kimberly M ^a   Gourronc, Francoise A ^a   Riley, Soraya ^a   Lansdorp, Peter M ^b,d   Goldman, Frederick D ^c   Klingelhutz, Aloysius J ^a  

^a UNIVERSITY OF IOWA   (United States)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Aging; Aplastic anemia; Dyskeratosis congenita; Gene therapy; Telomerase; Telomere; TER; TERT

Indexed keywords

TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CATALYSIS; CELL PROLIFERATION; CONTROLLED STUDY; DYSKERATOSIS CONGENITA; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EXPRESSION VECTOR; HUMAN; HUMAN CELL; LIFESPAN; PHENOTYPE; PRIORITY JOURNAL; SENESCENCE; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; TELOMERE;

AGING; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; DYSKERATOSIS CONGENITA; FIBROBLASTS; GENE THERAPY; GENES, DOMINANT; HUMANS; MODELS, BIOLOGICAL; MUTATION; RNA; TELOMERASE; TELOMERE; TIME FACTORS;

EID: 34249054511     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2007.00288.x     Document Type: Article

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