메뉴 건너뛰기




Volumn 102, Issue 5, 1998, Pages 938-946

Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjogren's syndrome

Author keywords

Autoimmunity; Germinal center; Immunoglobulin; Sjogren's syndrome; V gene

Indexed keywords

ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; GENE EXPRESSION; GENE MUTATION; GENE REARRANGEMENT; GERMINAL CENTER; HUMAN; HUMAN TISSUE; LYMPHOCYTE PROLIFERATION; MOLECULAR CLONING; PRIORITY JOURNAL; SALIVARY GLAND; SJOEGREN SYNDROME;

EID: 0032169223     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI3234     Document Type: Article
Times cited : (299)

References (47)
  • 1
    • 0001247099 scopus 로고
    • Sjögren's syndrome and connective tissue diseases associated with other immunologic disorders
    • D.J. McCarty and W.J. Knoopman, edilors. Lea & Febiger, Philadelphia
    • Talal, N. 1993. Sjögren's syndrome and connective tissue diseases associated with other immunologic disorders. In Arthritis and Allied Conditions. D.J. McCarty and W.J. Knoopman, edilors. Lea & Febiger, Philadelphia. 1343-1356.
    • (1993) Arthritis and Allied Conditions , pp. 1343-1356
    • Talal, N.1
  • 4
    • 0028020075 scopus 로고
    • Concentration of autoantibodies to native 60-kd Ro/SS-A and 52-kd Ro/SS-A in eluates from the heart of a child who died with congenital complete heart block
    • Reichlin, M., A. Brucato, M.B. Frank, P.J. Maddison, V.R. McCubhin, M. Wolfson-Reichlin, and L.A. Lee. 1994. Concentration of autoantibodies to native 60-kd Ro/SS-A and 52-kd Ro/SS-A in eluates from the heart of a child who died with congenital complete heart block. Arthritis Rheum. 37:1698-1703.
    • (1994) Arthritis Rheum. , vol.37 , pp. 1698-1703
    • Reichlin, M.1    Brucato, A.2    Frank, M.B.3    Maddison, P.J.4    McCubhin, V.R.5    Wolfson-Reichlin, M.6    Lee, L.A.7
  • 5
    • 0001926299 scopus 로고    scopus 로고
    • SS-A (Ro) autoantibodies
    • J.B. Peter and Y. Shoenfeld, editors. Elsevier, Amsterdam
    • Reichlin, M., and R.H. Scofield. 1996. SS-A (Ro) autoantibodies. In Autoantibodies. J.B. Peter and Y. Shoenfeld, editors. Elsevier, Amsterdam. 783-788.
    • (1996) Autoantibodies , pp. 783-788
    • Reichlin, M.1    Scofield, R.H.2
  • 6
    • 0001780631 scopus 로고    scopus 로고
    • SS-B (La) autoantibodies
    • J.B. Peter and Y. Shoenfeld, editors. Elsevier, Amsterdam
    • Keech, C.L., J. McCluskey, and T.P. Gordon. 1996. SS-B (La) autoantibodies. In Autoantibodies. J.B. Peter and Y. Shoenfeld, editors. Elsevier, Amsterdam. 789-797.
    • (1996) Autoantibodies , pp. 789-797
    • Keech, C.L.1    McCluskey, J.2    Gordon, T.P.3
  • 7
    • 0026013652 scopus 로고
    • Ro and La antigens and maternal anti-La idiotype on the surface of myocardial fibres in congenital heart block
    • Horsfall, A.C., P.J.W. Venables, P.V. Taylor, and R.N. Maini. 1991. Ro and La antigens and maternal anti-La idiotype on the surface of myocardial fibres in congenital heart block. J. Autoimmin. 4:165-176.
    • (1991) J. Autoimmin. , vol.4 , pp. 165-176
    • Horsfall, A.C.1    Venables, P.J.W.2    Taylor, P.V.3    Maini, R.N.4
  • 8
    • 0002025883 scopus 로고
    • C. Bona, K.A. Siminovitch, M. Zanetti, and A.N. Theofilopoulos, editors. Harwood, Lausanne
    • Bigazzi, P.E. 1993. The Molecular Pathology of Autoimmune Diseases. C. Bona, K.A. Siminovitch, M. Zanetti, and A.N. Theofilopoulos, editors. Harwood, Lausanne. 493-510.
    • (1993) The Molecular Pathology of Autoimmune Diseases , pp. 493-510
    • Bigazzi, P.E.1
  • 9
    • 0024713653 scopus 로고
    • Autoantibody synthesis in salivary glands of Sjogren's syndrome patients
    • Horsfall, A.C., L.M. Rose, and R.N. Maini. 1989. Autoantibody synthesis in salivary glands of Sjogren's syndrome patients. J. Autoimmun. 2:559-568.
    • (1989) J. Autoimmun. , vol.2 , pp. 559-568
    • Horsfall, A.C.1    Rose, L.M.2    Maini, R.N.3
  • 11
    • 0021339874 scopus 로고
    • Immunohistologic characterization of synovial membrane lymphocytes in rheumatoid arthritis
    • Young, C.L., T.C. Adamson, J.H. Vaughan, and R.I. Fox. 1984. Immunohistologic characterization of synovial membrane lymphocytes in rheumatoid arthritis. Arthritis Rheum. 27:32-39.
    • (1984) Arthritis Rheum. , vol.27 , pp. 32-39
    • Young, C.L.1    Adamson, T.C.2    Vaughan, J.H.3    Fox, R.I.4
  • 12
    • 0019492576 scopus 로고
    • Immunohistological findings in Hashimoto's thyroiditis, focal lymphocytic thyroiditis and thyroiditis de Ouervain. Comparative study
    • Knecht, H., P. Saremaslani, and C. Hedinger. 1981. Immunohistological findings in Hashimoto's thyroiditis, focal lymphocytic thyroiditis and thyroiditis de Ouervain. Comparative study. Virchows Archiv-Abteilung A Pathologische Anatomie. 393:215-231.
    • (1981) Virchows Archiv-Abteilung A Pathologische Anatomie , vol.393 , pp. 215-231
    • Knecht, H.1    Saremaslani, P.2    Hedinger, C.3
  • 13
    • 0027537847 scopus 로고
    • The intraportal lymphoid nodule and its environment in chronic active hepatitis C: An immunohistochemical study
    • Mosnier, J.-F., C. Degott, P. Marcellin, D. Henin, S. Erlinger, and J.-P. Benhamou. 1993. The intraportal lymphoid nodule and its environment in chronic active hepatitis C: an immunohistochemical study. Hepatology. 17:366-371.
    • (1993) Hepatology , vol.17 , pp. 366-371
    • Mosnier, J.-F.1    Degott, C.2    Marcellin, P.3    Henin, D.4    Erlinger, S.5    Benhamou, J.-P.6
  • 15
    • 0029986068 scopus 로고    scopus 로고
    • The immunological architecture of B-lymphocyte aggregates in cryptogenic fibrosing alveolitis
    • Wallace, W.A.H., S.E.M. Howie, A.S. Krajewski, and D. Lamb. 1996. The immunological architecture of B-lymphocyte aggregates in cryptogenic fibrosing alveolitis. J. Pathol. 178:323-329.
    • (1996) J. Pathol. , vol.178 , pp. 323-329
    • Wallace, W.A.H.1    Howie, S.E.M.2    Krajewski, A.S.3    Lamb, D.4
  • 17
    • 0028907577 scopus 로고
    • The identification of germinal centres and follicular dendritic cell networks in rheumatoid synovial tissue
    • Randen, I., O.J. Mellbye. Ø. Forre, and J.B. Natvig. 1995. The identification of germinal centres and follicular dendritic cell networks in rheumatoid synovial tissue. Scand. J. Immimol. 41:481-486.
    • (1995) Scand. J. Immimol. , vol.41 , pp. 481-486
    • Randen, I.1    Mellbye, O.J.2    Forre, Ø.3    Natvig, J.B.4
  • 18
    • 0030070295 scopus 로고    scopus 로고
    • Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis
    • Schröder, A.E., G. Greiner, C. Seyfert, and C. Berek. 1996. Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis. Proc. Natl. Acad. Sci. USA. 93:221-225.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 221-225
    • Schröder, A.E.1    Greiner, G.2    Seyfert, C.3    Berek, C.4
  • 19
    • 0025760317 scopus 로고
    • Oligonucleotide primers for polymerase chain reaction amplification of human immunoglobulin variable genes and design of family-specific oligonucleotide probes
    • Marks, J.D., M. Tristem, A. Karpas, and G. Winter. 1991. Oligonucleotide primers for polymerase chain reaction amplification of human immunoglobulin variable genes and design of family-specific oligonucleotide probes. Eur. J. Immunol. 21:985-991.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 985-991
    • Marks, J.D.1    Tristem, M.2    Karpas, A.3    Winter, G.4
  • 21
    • 0028128577 scopus 로고
    • Development of antibody diversity in single germinal centers: Selective expansion of high affinity variants
    • Ziegner, M., G. Steinhauser, and C. Berek. 1994. Development of antibody diversity in single germinal centers: selective expansion of high affinity variants. Eur. J. Immunol. 24:2393-2400.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2393-2400
    • Ziegner, M.1    Steinhauser, G.2    Berek, C.3
  • 22
    • 0031569118 scopus 로고    scopus 로고
    • Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes
    • Dorner, T., H.-P. Brezinschek, R.I. Brezinschek, S.J. Foster, R. Domiati-Saad, and P.E. Lipsky. 1997. Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes. J. Immunol. 158:2779-2789.
    • (1997) J. Immunol. , vol.158 , pp. 2779-2789
    • Dorner, T.1    Brezinschek, H.-P.2    Brezinschek, R.I.3    Foster, S.J.4    Domiati-Saad, R.5    Lipsky, P.E.6
  • 23
    • 0004886564 scopus 로고
    • The influence of somatic mutation on the immune response
    • Weigert, M. 1986. The influence of somatic mutation on the immune response. Prog. Immunol. 6:138-142.
    • (1986) Prog. Immunol. , vol.6 , pp. 138-142
    • Weigert, M.1
  • 25
    • 0018179467 scopus 로고
    • Analysis of the repertoire of anti-NP antibodies in C57BL/6 mice by cell fusion. 1. Characterization of antibody families in the primary and hyperimmune response
    • Reth, M., G.J. Hammerling, and K. Rajewsky. 1978. Analysis of the repertoire of anti-NP antibodies in C57BL/6 mice by cell fusion. 1. Characterization of antibody families in the primary and hyperimmune response. Eur. J. Immunol. 8:393-400.
    • (1978) Eur. J. Immunol. , vol.8 , pp. 393-400
    • Reth, M.1    Hammerling, G.J.2    Rajewsky, K.3
  • 26
    • 0021711720 scopus 로고
    • Somatic mutation and the maturation of immune response to 2-phenyloxazolone
    • Griffiths, G.M., C. Berek, M. Kaartinen, and C. Milstein. 1984. Somatic mutation and the maturation of immune response to 2-phenyloxazolone. Nature. 312:271-275.
    • (1984) Nature , vol.312 , pp. 271-275
    • Griffiths, G.M.1    Berek, C.2    Kaartinen, M.3    Milstein, C.4
  • 27
    • 0020534350 scopus 로고
    • mRNA sequences define an unusually restricted IgG response to 2-phenylox-azolone and its early diversification
    • Kaartinen, M., G.M. Griffiths, A.F. Markham, and C. Milstein. 1983. mRNA sequences define an unusually restricted IgG response to 2-phenylox-azolone and its early diversification. Nature. 304:320-324.
    • (1983) Nature , vol.304 , pp. 320-324
    • Kaartinen, M.1    Griffiths, G.M.2    Markham, A.F.3    Milstein, C.4
  • 28
    • 0023161405 scopus 로고
    • Evolution of antibody variable region structure during the immune response
    • Manser, T., L.J. Wysocki, M.N. Margolics, and M.L. Gefter. 1987. Evolution of antibody variable region structure during the immune response. Immunol. Rev. 96:141-162.
    • (1987) Immunol. Rev. , vol.96 , pp. 141-162
    • Manser, T.1    Wysocki, L.J.2    Margolics, M.N.3    Gefter, M.L.4
  • 29
    • 0022503258 scopus 로고
    • Somatic evolution of variable region structures during an immune response
    • Wysocki, L., T. Manser, and M.L. Gefter. 1986. Somatic evolution of variable region structures during an immune response. Proc. Natl. Acab. Sci. USA. 83:1847-1851.
    • (1986) Proc. Natl. Acab. Sci. USA , vol.83 , pp. 1847-1851
    • Wysocki, L.1    Manser, T.2    Gefter, M.L.3
  • 30
    • 0024546494 scopus 로고
    • Naturally occurring antibodies to bovine and human retinal S antigens; a comparison between uveitis patients and normal healthy volunteers
    • Forrester, J.V., D.I. Stott, and K.M. Hercus. 1989. Naturally occurring antibodies to bovine and human retinal S antigens; a comparison between uveitis patients and normal healthy volunteers. Br. J. Ophthalmol. 73:155-159.
    • (1989) Br. J. Ophthalmol. , vol.73 , pp. 155-159
    • Forrester, J.V.1    Stott, D.I.2    Hercus, K.M.3
  • 31
    • 0026742048 scopus 로고
    • Spectrotypes of anti-DNA antibodies show that anti-DNA-secreting B cell clones of SLE patients are restricted in number, stable and long lived
    • Stott, D.I. 1992. Spectrotypes of anti-DNA antibodies show that anti-DNA-secreting B cell clones of SLE patients are restricted in number, stable and long lived. Autoimmunity. 12:249-258.
    • (1992) Autoimmunity , vol.12 , pp. 249-258
    • Stott, D.I.1
  • 32
    • 0022482059 scopus 로고
    • Analysis of the clonal origins of autoantibodies against thyroglobulin and DNA in autoimmune thyroiditis and systemic lupus erythematosus
    • Stott, D.I., J. McLearie, and L. Neilson. 1986. Analysis of the clonal origins of autoantibodies against thyroglobulin and DNA in autoimmune thyroiditis and systemic lupus erythematosus. Clin. Exp. Immunol. 65:520-533.
    • (1986) Clin. Exp. Immunol. , vol.65 , pp. 520-533
    • Stott, D.I.1    McLearie, J.2    Neilson, L.3
  • 33
    • 0023150572 scopus 로고
    • Uniform detection of immunoglobulin-gene rearrangement in benign lymphoepithelial lesions
    • Fishleder, A., R. Tubbs, B. Hesse, and H. Levine. 1987. Uniform detection of immunoglobulin-gene rearrangement in benign lymphoepithelial lesions. N. Engl. J. Med. 316:1118-1121.
    • (1987) N. Engl. J. Med. , vol.316 , pp. 1118-1121
    • Fishleder, A.1    Tubbs, R.2    Hesse, B.3    Levine, H.4
  • 36
    • 0027222545 scopus 로고
    • A single neoplastic clone in sequential biopsy specimens from a patient with primary gastric-mucosa-associated lymphoid-tissue lymphoma and Sjögren's syndrome
    • Diss, T.C., H. Peng, A.C. Wotherspoon, L. Pan, P.M. Speight, and P.G. Isaacson. 1993. A single neoplastic clone in sequential biopsy specimens from a patient with primary gastric-mucosa-associated lymphoid-tissue lymphoma and Sjögren's syndrome. N. Engl. J. Med. 329:172-175.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 172-175
    • Diss, T.C.1    Peng, H.2    Wotherspoon, A.C.3    Pan, L.4    Speight, P.M.5    Isaacson, P.G.6
  • 37
    • 0030988806 scopus 로고    scopus 로고
    • Ongoing Ig gene hypermutation in salivary gland mucosa-associated lymphoid tissue-type lymphomas
    • Bahler, D.W., J.A. Miklos, and S.H. Swedlow. 1997. Ongoing Ig gene hypermutation in salivary gland mucosa-associated lymphoid tissue-type lymphomas. Blood. 89:3335-3344.
    • (1997) Blood , vol.89 , pp. 3335-3344
    • Bahler, D.W.1    Miklos, J.A.2    Swedlow, S.H.3
  • 39
    • 0027491651 scopus 로고
    • Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections
    • Küppers, R., M. Zhao, M.-L Hansmann, and K. Rajewsky. 1993. Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections. EMBO J. 12:4955-4967.
    • (1993) EMBO J. , vol.12 , pp. 4955-4967
    • Küppers, R.1    Zhao, M.2    Hansmann, M.-L.3    Rajewsky, K.4
  • 40
    • 0024309563 scopus 로고
    • Molecular characterization of a major autoantibody-associated cross-reactive idiotype in Sjögren's syndrome
    • Kipps, T.J., E. Tomhave, P.P. Chen, and R.I. Fox. 1989. Molecular characterization of a major autoantibody-associated cross-reactive idiotype in Sjögren's syndrome. J. Immunol. 142:4261-4268.
    • (1989) J. Immunol. , vol.142 , pp. 4261-4268
    • Kipps, T.J.1    Tomhave, E.2    Chen, P.P.3    Fox, R.I.4
  • 41
    • 0001578946 scopus 로고
    • The influence of somatic mutation on clonal expansion
    • Shlomchik, M., S. Lilwin, and M. Weigert. 1989. The influence of somatic mutation on clonal expansion. Prog. Immunol. 7:415-423.
    • (1989) Prog. Immunol. , vol.7 , pp. 415-423
    • Shlomchik, M.1    Lilwin, S.2    Weigert, M.3
  • 42
    • 0028577302 scopus 로고
    • Control of autoantibody affinity by selection against amino acid replacements in the complementarity-determining regions
    • Børretzen, M., I. Randen, E. Zdarsky, F. Øystein, J.B. Natvig, and K.M. Thompson. 1994. Control of autoantibody affinity by selection against amino acid replacements in the complementarity-determining regions. Proc. Natl. Acad. Sci. USA. 91:12917-12921.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12917-12921
    • Børretzen, M.1    Randen, I.2    Zdarsky, E.3    Øystein, F.4    Natvig, J.B.5    Thompson, K.M.6
  • 44
    • 0028970664 scopus 로고
    • The etiopathogenesis of Sjögren's syndrome
    • Price, E.J., and P.J.W. Venables. 1995. The etiopathogenesis of Sjögren's syndrome. Sem. Arthr. Rheum. 25:117-133.
    • (1995) Sem. Arthr. Rheum. , vol.25 , pp. 117-133
    • Price, E.J.1    Venables, P.J.W.2
  • 45
    • 0026670190 scopus 로고
    • In situ studies of the primary immune response to (4-hvdroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers
    • Jacob, J., and G. Kelsoe. 1992. In situ studies of the primary immune response to (4-hvdroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers. J. Exp. Med. 176:679-687.
    • (1992) J. Exp. Med. , vol.176 , pp. 679-687
    • Jacob, J.1    Kelsoe, G.2
  • 46
    • 0000361112 scopus 로고
    • Myasthenia gravis as an example of organ-specific autoimmune disease
    • G. Bird and J.E. Calvert, editors. Oxford University Press, Oxford
    • Willcox, N., and A. Vincent. 1988. Myasthenia gravis as an example of organ-specific autoimmune disease. In B Lymphocytes in Human Disease. G. Bird and J.E. Calvert, editors. Oxford University Press, Oxford. 469-506.
    • (1988) B Lymphocytes in Human Disease , pp. 469-506
    • Willcox, N.1    Vincent, A.2
  • 47
    • 0029080070 scopus 로고
    • Focal lymphocytic aggregates in chronic hepatitis C: Occurrence, immunohistochemical characterization, and relation to markers of autoimmunity
    • Freni, M.A., D. Artuso, G. Gerken, C. Spanti, T. Marafioti, N. Alessi, A. Spadaro, A. Ajello, and O. Ferrau. 1995. Focal lymphocytic aggregates in chronic hepatitis C: occurrence, immunohistochemical characterization, and relation to markers of autoimmunity. Hepatology. 22:389-394.
    • (1995) Hepatology , vol.22 , pp. 389-394
    • Freni, M.A.1    Artuso, D.2    Gerken, G.3    Spanti, C.4    Marafioti, T.5    Alessi, N.6    Spadaro, A.7    Ajello, A.8    Ferrau, O.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.