Azole fungicides affect mammalian steroidogenesis by inhibiting sterol 14α-demethylase and aromatase

Environmental Health Perspectives

Volumn 111, Issue 3, 2003, Pages 255-261

  Zarn, Jürg A ^a   Brüschweiler, Beat J ^a   Schlatter, Josef R ^a  

^a FEDERAL OFFICE OF PUBLIC HEALTH   (Switzerland)

Author keywords

Aromatase; CYP19; CYP51; Endocrine disruption; Follicle fluid meiosis activating sterol (FF MAS); Lanosterol; Meiosis activating sterols; Sterol 14 demethylase; Testis meiosis activating sterol (T MAS)

Indexed keywords

AMPHOTERICIN B; ANASTROZOLE; ANDROGEN; ANTIESTROGEN; AROMATASE; CLOTRIMAZOLE; CYTOCHROME P450; ECONAZOLE; ESTROGEN; FADROZOLE; FENTICONAZOLE; FLUCONAZOLE; FUNGICIDE; IMIDAZOLE; ISOCONAZOLE; ITRACONAZOLE; KETOCONAZOLE; LETROZOLE; MICONAZOLE; OXICONAZOLE; PYRROLE DERIVATIVE; STEROID; STEROL; STEROL 14ALPHA DEMETHYLASE; TAMOXIFEN; TERCONAZOLE; TIOCONAZOLE; TRIAZOLE; UNINDEXED DRUG; VOROZOLE;

AGRICULTURE; BINDING AFFINITY; BREAST TUMOR; CELL MATURATION; CHEMICAL STRUCTURE; DRUG POTENCY; ENZYME BINDING; ENZYME INHIBITION; ENZYME SPECIFICITY; GERM CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MAMMAL; MEIOSIS; MYCOSIS; NONHUMAN; POSTMENOPAUSE; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; STEROIDOGENESIS;

ANIMALIA; MAMMALIA;

EID: 0037351102     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.5785     Document Type: Review

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