Toxicogenomics of subchronic hexachlorobenzene exposure in Brown Norway rats

Environmental Health Perspectives

Volumn 112, Issue 7, 2004, Pages 782-791

  Ezendam, Janine ^a,b,c   Staedtler, Frank ^d   Pennings, Jeroen ^b   Vandebriel, Rob J ^b   Pieters, Raymond ^a   Harleman, Johannes H ^d   Vos, Joseph G ^b,c  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

^d NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Brown Norway rat; DNA microarray analysis; Drug metabolism; Estrogen metabolism; Genomics; Hexachlorobenzene; Immunotoxicity; Inflammation; Oxidative stress; Porphyria

Indexed keywords

ACUTE PHASE PROTEIN; ANTIOXIDANT; CELL ADHESION MOLECULE; CELL MARKER; CHEMOKINE; COMPLEMENT; CYTOKINE; DNA; GENE PRODUCT; HEXACHLOROBENZENE;

ACUTE PHASE RESPONSE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DNA MICROARRAY; DRUG METABOLISM; ENVIRONMENTAL EXPOSURE; ENZYME INDUCTION; FEMALE; FOOD INTAKE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC CODE; GENETIC TOXICOLOGY; GENITAL SYSTEM DISEASE; GRANULOCYTE; HEPATIC PORPHYRIA; HISTOPATHOLOGY; IMMUNOPATHOLOGY; IMMUNOTOXICITY; KIDNEY PARENCHYMA; LIVER PARENCHYMA; MACROPHAGE; MAST CELL; MESENTERY LYMPH NODE; NEUROLOGIC DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POLLUTANT; PRIORITY JOURNAL; RAT; SPLEEN; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THYMUS; UNINDEXED SEQUENCE; UPREGULATION;

ANIMALIA; EUKARYOTA; RATTUS NORVEGICUS;

EID: 2642576049     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.112-1241993     Document Type: Article

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