Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway

GLIA

Volumn 59, Issue 4, 2011, Pages 554-568

  Calvo, Margarita ^a   Zhu, Ning ^a   Grist, John ^a   Ma, Zhenzhong ^b   Loeb, Jeffrey A ^b   Bennett, David L H ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AKT; ErbB receptors; ERK1 2; Microgliosis; Neuregulin 1; Neuropathic pain

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEU DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; COLD SENSITIVITY; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME INHIBITION; IN VITRO STUDY; MALE; MICROGLIA; NEUROPATHIC PAIN; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; IMMUNOHISTOCHEMISTRY; MALE; MAP KINASE SIGNALING SYSTEM; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; NEURALGIA; NEUREGULIN-1; PERIPHERAL NERVES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR;

EID: 79851498855     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.21124     Document Type: Article

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