Activation of Src-family kinases in spinal microglia contributes to mechanical hypersensitivity after nerve injury

Journal of Neuroscience

Volumn 26, Issue 34, 2006, Pages 8680-8690

  Katsura, Hirokazu ^a   Obata, Koichi ^a   Mizushima, Toshiyuki ^a   Sakurai, Jun ^a   Kobayashi, Kimiko ^a   Yamanaka, Hiroki ^a   Dai, Yi ^a   Fukuoka, Tetsuo ^a   Sakagami, Masafumi ^a   Noguchi, Koichi ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Extracellular signal regulated protein kinase; Microglia; Neuropathic pain; p38 mitogen activated protein kinase; Spinal cord; Src family kinase

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN TYROSINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL DIFFERENTIATION; CELL PROLIFERATION; COLD SENSITIVITY; CONTROLLED STUDY; DRUG EFFECT; HEAT SENSITIVITY; HYPERSENSITIVITY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MECHANICAL STIMULATION; MICROGLIA; NERVE CELL; NERVE CELL PLASTICITY; NERVE INJURY; NEUROPATHIC PAIN; NONHUMAN; PERIPHERAL NERVE INJURY; PHOSPHORYLATION; PRIORITY JOURNAL; RAT; SPINAL CORD; WESTERN BLOTTING;

ANIMALS; CALCIUM CHANNELS; COLD; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEAT; HYPERALGESIA; LUMBOSACRAL REGION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MALE; MICROGLIA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SPINAL NERVES; SRC-FAMILY KINASES; TRAUMA, NERVOUS SYSTEM; TRPV CATION CHANNELS;

EID: 33748279280     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1771-06.2006     Document Type: Article

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