Targeting human epidermal growth factor receptor signaling with the Neuregulin's heparin-binding domain

Journal of Biological Chemistry

Volumn 284, Issue 46, 2009, Pages 32108-32115

  Ma, Zhenzhong ^a   Ii, Qunfang ^a   An, Haiqian ^a   Pankonin, Mark S ^a   Wang, Jiajing ^a   Loeb, Jeffrey A ^a,b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER CELLS; CANCER CELLS; CELL SURFACES; CELL-SURFACE HEPARAN; DISEASED TISSUES; FUSION PROTEINS; GROWTH FACTOR; HEPARAN SULFATES; HEPARIN BINDING; HIGH AFFINITY; HUMAN EPIDERMAL GROWTH FACTOR; IN-VIVO; NERVOUS SYSTEM DEVELOPMENT; NEUREGULIN; PARACRINE; PERIPHERAL NERVES; SCHWANN CELLS;

BIOACTIVITY; CELL MEMBRANES; PEPTIDES; SIGNALING;

POLYSACCHARIDES;

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 4 HEPARIN BINDING DOMAIN FUSION PROTEIN; HEPARAN SULFATE; HYBRID PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; BINDING AFFINITY; BREAST CANCER; CANCER CELL; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; DRUG TARGETING; EMBRYO; NONHUMAN; PARACRINE SIGNALING; PERIPHERAL NERVE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SCHWANN CELL; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; AUTOCRINE COMMUNICATION; BREAST NEOPLASMS; CELL PROLIFERATION; CHICK EMBRYO; CHO CELLS; CRICETINAE; CRICETULUS; FEMALE; HEPARIN; HEPARITIN SULFATE; HUMANS; MOLECULAR SEQUENCE DATA; NEUREGULIN-1; PARACRINE COMMUNICATION; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; SCHWANN CELLS;

EID: 70450236983     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.032714     Document Type: Article

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