Activation of p38 Mitogen-Activated Protein Kinase in Spinal Hyperactive Microglia Contributes to Pain Hypersensitivity Following Peripheral Nerve Injury

GLIA

Volumn 45, Issue 1, 2004, Pages 89-95

  Tsuda, Makoto ^a,c   Mizokoshi, Akito ^b   Shigemoto Mogami, Yukari ^a   Koizumi, Schuichi ^a   Inoue, Kazuhide ^a,b  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Dorsal horn; Mitogen activated protein kinases; Neuropathic pain; Tactile allodynia

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HYPERALGESIA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; NEUROPATHIC PAIN; NONHUMAN; PERIPHERAL NERVE INJURY; PHENOTYPE; RAT; SPINAL CORD DORSAL HORN; SPINAL CORD NERVE CELL; TACTILE ALLODYNIA; WESTERN BLOTTING;

ANIMALS; ENZYME ACTIVATION; MALE; MAP KINASE SIGNALING SYSTEM; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PAIN; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, WISTAR; SPINAL CORD; SPINAL NERVES;

EID: 0346655315     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/glia.10308     Document Type: Article

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