Molecular mechanisms regulating the mitochondrial targeting of microsomal cytochrome P450 enzymes

Current Drug Metabolism

Volumn 11, Issue 10, 2010, Pages 830-838

  Ahn, Taeho ^a   Yun, Chul Ho ^a  

^a Chonnam National University   (South Korea)

Author keywords

Cytochrome P450; Drug metabolism; Microsome; Mitochondria; Signal sequence; Targeting

Indexed keywords

AFLATOXIN B1; ANANDAMIDE; ANTICONVULSIVE AGENT; BENZO[A]PYRENE; BETA NAPHTHOFLAVONE; CALCITRIOL; COLECALCIFEROL; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; CYTOCHROME P450 3A1; CYTOCHROME P450 3A2; CYTOCHROME P450 3A4; DIAZEPAM; EPOXYICOSATRIENOIC ACID; ERGOCALCIFEROL; ERYTHROMYCIN; MICROSOME ENZYME; MORPHINE; OPIATE; PHENOBARBITAL; TRICYCLIC ANTIDEPRESSANT AGENT; VITAMIN D; XENOBIOTIC AGENT;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BRAIN; BRAIN MITOCHONDRION; CANCER CELL; CATALYSIS; CELL LINE; CELL MEMBRANE; CYTOSOL; CYTOTOXICITY; DRUG INHIBITION; DRUG MECHANISM; DRUG METABOLISM; DRUG POTENCY; ELECTRON; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME METABOLISM; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIVER; LIVER MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN TARGETING; REGULATORY MECHANISM; SWINE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; ENDOPLASMIC RETICULUM; HUMANS; ISOENZYMES; MICROSOMES; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; SUBSTRATE SPECIFICITY;

EID: 79851481559     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920010794479655     Document Type: Article

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