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Volumn 65, Issue 9, 2005, Pages 3726-3734

Overexpression of cytochrome P450 1A1 and its novel spliced variant in ovarian cancer cells: Alternative subcellular enzyme compartmentation may contribute to carcinogenesis

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE DERIVATIVE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A1 1V; CYTOCHROME P450 1A1 WT; ESTRADIOL; ETHOXYRESORUFIN DEETHYLASE; UNCLASSIFIED DRUG;

EID: 18144383865     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-3771     Document Type: Article
Times cited : (49)

References (49)
  • 1
    • 0033936074 scopus 로고    scopus 로고
    • Ovarian cancer: Epidemiology, biology, and prognostic factors
    • Holschneider CH, Berek JS. Ovarian cancer: epidemiology, biology, and prognostic factors. Semin Surg Oncol 2000;19:3-10.
    • (2000) Semin Surg Oncol , vol.19 , pp. 3-10
    • Holschneider, C.H.1    Berek, J.S.2
  • 2
    • 0035885338 scopus 로고    scopus 로고
    • Diet and ovarian cancer risk: A case-control study in Italy
    • Bosetti C, Negri E, Franceschi S, et al. Diet and ovarian cancer risk: a case-control study in Italy. Int J Cancer 2001;93:911-5.
    • (2001) Int J Cancer , vol.93 , pp. 911-915
    • Bosetti, C.1    Negri, E.2    Franceschi, S.3
  • 3
    • 0033809154 scopus 로고    scopus 로고
    • Population based study of coffee, alcohol and tobacco use and risk of ovarian cancer
    • Kuper H, Titus-Ernstoff L, Harlow BL, et al. Population based study of coffee, alcohol and tobacco use and risk of ovarian cancer. Int J Cancer 2000;88:313-8.
    • (2000) Int J Cancer , vol.88 , pp. 313-318
    • Kuper, H.1    Titus-Ernstoff, L.2    Harlow, B.L.3
  • 4
    • 0033984065 scopus 로고    scopus 로고
    • Cigarette smoking and epithelial ovarian cancer by histologic type
    • Marchbanks PA, Wilson H, Bastos E, et al. Cigarette smoking and epithelial ovarian cancer by histologic type. Obstet Gynecol 2000;95:255-60.
    • (2000) Obstet Gynecol , vol.95 , pp. 255-260
    • Marchbanks, P.A.1    Wilson, H.2    Bastos, E.3
  • 5
    • 0032836490 scopus 로고    scopus 로고
    • Inhibition of BRCA-1 expression by benzo[a]pyrene and its diol epoxide
    • Jeffy BD, Schultz EU, Selmin O, et al. Inhibition of BRCA-1 expression by benzo[a]pyrene and its diol epoxide. Mol Carcinog 1999;26:100-18.
    • (1999) Mol Carcinog , vol.26 , pp. 100-118
    • Jeffy, B.D.1    Schultz, E.U.2    Selmin, O.3
  • 7
    • 0034307290 scopus 로고    scopus 로고
    • Ovarian tumors in rats induced by chronic 2,3,7,8-tetrachlorodibenzo-p- dioxin treatment
    • Davis BJ, Mccurdy EA, Miller BD, et al. Ovarian tumors in rats induced by chronic 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment. Cancer Res 2000;60:5414-9.
    • (2000) Cancer Res , vol.60 , pp. 5414-5419
    • Davis, B.J.1    Mccurdy, E.A.2    Miller, B.D.3
  • 8
    • 0027744421 scopus 로고
    • Cancer in a young population in a dioxin-contaminated area
    • Pesatori AC, Consonni D, Tironi A, et al. Cancer in a young population in a dioxin-contaminated area. Int J Epidemiol 1993;22:1010-3.
    • (1993) Int J Epidemiol , vol.22 , pp. 1010-1013
    • Pesatori, A.C.1    Consonni, D.2    Tironi, A.3
  • 9
    • 0033655698 scopus 로고    scopus 로고
    • Endogenous estrogens as carcinogens through metabolic activation
    • Yager JD. Endogenous estrogens as carcinogens through metabolic activation. J Natl Cancer Inst Monogr 2000;67-73.
    • (2000) J Natl Cancer Inst Monogr , pp. 67-73
    • Yager, J.D.1
  • 10
    • 0242662678 scopus 로고    scopus 로고
    • Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells
    • Russo J, Hasan LM, Balogh G, et al. Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells. J Steroid Biochem Mol Biol 2003;87:1-25.
    • (2003) J Steroid Biochem Mol Biol , vol.87 , pp. 1-25
    • Russo, J.1    Hasan, L.M.2    Balogh, G.3
  • 11
    • 4344605682 scopus 로고    scopus 로고
    • Estrogen, progesterone and epithelial ovarian cancer
    • Ho SM. Estrogen, progesterone and epithelial ovarian cancer. Reprod Biol Endocrinol 2003;1:73.
    • (2003) Reprod Biol Endocrinol , vol.1 , pp. 73
    • Ho, S.M.1
  • 12
    • 2942594342 scopus 로고    scopus 로고
    • Oxidative damage to DNA of ovarian surface epithelial cells affected by ovulation: Carcinogenic implication and chemoprevention
    • Murdoch WJ, Martinchick JF. Oxidative damage to DNA of ovarian surface epithelial cells affected by ovulation: carcinogenic implication and chemoprevention. Exp Biol Med (Maywood) 2004;229:546-52.
    • (2004) Exp Biol Med (Maywood) , vol.229 , pp. 546-552
    • Murdoch, W.J.1    Martinchick, J.F.2
  • 13
    • 0028557312 scopus 로고
    • Functional significance of different human CYP1A1 genotypes
    • Crofts F, Taioli E, Trachman J, et al. Functional significance of different human CYP1A1 genotypes. Carcinogenesis 1994;15:2961-3.
    • (1994) Carcinogenesis , vol.15 , pp. 2961-2963
    • Crofts, F.1    Taioli, E.2    Trachman, J.3
  • 14
    • 0037357910 scopus 로고    scopus 로고
    • Interaction between CYP1A1 polymorphic variants and dietary exposures influencing ovarian cancer risk
    • Terry KL, Titus-Ernstoff L, Garner EO, et al. Interaction between CYP1A1 polymorphic variants and dietary exposures influencing ovarian cancer risk. Cancer Epidemiol Biomarkers Prev 2003;12:187-90.
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12 , pp. 187-190
    • Terry, K.L.1    Titus-Ernstoff, L.2    Garner, E.O.3
  • 15
    • 0036353509 scopus 로고    scopus 로고
    • CYP1A1 gene polymorphism and risk of epithelial ovarian neoplasm
    • Aktas D, Guney I, Alikasifoglu M, et al. CYP1A1 gene polymorphism and risk of epithelial ovarian neoplasm. Gynecol Oncol 2002;86:124-8.
    • (2002) Gynecol Oncol , vol.86 , pp. 124-128
    • Aktas, D.1    Guney, I.2    Alikasifoglu, M.3
  • 16
    • 0035731881 scopus 로고    scopus 로고
    • Case-control study of ovarian cancer and polymorphisms in genes involved in catecholestrogen formation and metabolism
    • Goodman MT, McDuffie K, Kolonel LN et al. Case-control study of ovarian cancer and polymorphisms in genes involved in catecholestrogen formation and metabolism. Cancer Epidemiol Biomarkers Prev 2001;10:209-16.
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , pp. 209-216
    • Goodman, M.T.1    McDuffie, K.2    Kolonel, L.N.3
  • 17
    • 0036534129 scopus 로고    scopus 로고
    • Alternative splicing: Multiple control mechanisms and involvement in human disease
    • Caceres JF, Kornblihtt AR. Alternative splicing: Multiple control mechanisms and involvement in human disease. Trends Genet 2002;18:186-93.
    • (2002) Trends Genet , vol.18 , pp. 186-193
    • Caceres, J.F.1    Kornblihtt, A.R.2
  • 18
    • 0034326362 scopus 로고    scopus 로고
    • Analysis of canonical and non-canonical splice sites mammalian genomes
    • Burset M, Seledtsov IA, Solovyev W. Analysis of canonical and non-canonical splice sites mammalian genomes. Nucleic Acids Res 2000;28:4364-75.
    • (2000) Nucleic Acids Res , vol.28 , pp. 4364-4375
    • Burset, M.1    Seledtsov, I.A.2    Solovyev, V.V.3
  • 19
    • 0030995509 scopus 로고    scopus 로고
    • Pre-mRNA splicing: The discovery of a new spliceosome doubles the challenge
    • Tarn WY, Steitz JA. Pre-mRNA splicing: the discovery of a new spliceosome doubles the challenge. Trends Biochem Sci 1997;22:132-7.
    • (1997) Trends Biochem Sci , vol.22 , pp. 132-137
    • Tarn, W.Y.1    Steitz, J.A.2
  • 20
    • 0037084825 scopus 로고    scopus 로고
    • Categorization and characterization of transcript-confirmed constitutively and alternatively spliced introns and exons from human
    • Clark F, Thanaraj TA. Categorization and characterization of transcript-confirmed constitutively and alternatively spliced introns and exons from human. Hum Mol Genet 2002;11:451-64.
    • (2002) Hum Mol Genet , vol.11 , pp. 451-464
    • Clark, F.1    Thanaraj, T.A.2
  • 21
    • 0030989517 scopus 로고    scopus 로고
    • Removal of a cryptic intron and subcellular localization of green fluorescent protein are required to mark transgenic Arabidopsis plants brightly
    • Haseloff J, Siemering KR. Prasher DC, et al. Removal of a cryptic intron and subcellular localization of green fluorescent protein are required to mark transgenic Arabidopsis plants brightly. Proc Natl Acad Sci U S A 1997;94:2122-7.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 2122-2127
    • Haseloff, J.1    Siemering, K.R.2    Prasher, D.C.3
  • 22
    • 0029050422 scopus 로고
    • Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV-E6E7 ORFs)
    • Tsao SW, Mok SC, Fey EG, et al. Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV-E6E7 ORFs). Exp Cell Res 1995;218:499-507.
    • (1995) Exp Cell Res , vol.218 , pp. 499-507
    • Tsao, S.W.1    Mok, S.C.2    Fey, E.G.3
  • 23
    • 0035884589 scopus 로고    scopus 로고
    • Expression of gonadotropin receptor and growth responses to key reproductive hormones in normal and malignant human ovarian surface epithelial cells
    • Syed V, Ulinski G, Mok SC, et al. Expression of gonadotropin receptor and growth responses to key reproductive hormones in normal and malignant human ovarian surface epithelial cells. Cancer Res 2001;61:6768-76.
    • (2001) Cancer Res , vol.61 , pp. 6768-6776
    • Syed, V.1    Ulinski, G.2    Mok, S.C.3
  • 24
    • 0033545858 scopus 로고    scopus 로고
    • Expression of human estrogen receptor-α and -β, progesterone receptor, and androgen receptor mRNA in normal and malignant ovarian epithelial cells
    • Lau KM, Mok SC, Ho SM. Expression of human estrogen receptor-α and -β, progesterone receptor, and androgen receptor mRNA in normal and malignant ovarian epithelial cells. Proc Natl Acad Sci U S A 1999;96:5722-7.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5722-5727
    • Lau, K.M.1    Mok, S.C.2    Ho, S.M.3
  • 25
    • 0035408472 scopus 로고    scopus 로고
    • Comparative studies of the estrogen receptors β and α and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastaic carcinoma
    • Leav I, Lau KM, Adams JY, et al. Comparative studies of the estrogen receptors β and α and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastatic carcinoma. Am J Pathol 2001;159:79-92.
    • (2001) Am J Pathol , vol.159 , pp. 79-92
    • Leav, I.1    Lau, K.M.2    Adams, J.Y.3
  • 26
    • 0037025336 scopus 로고    scopus 로고
    • Transcriptional induction of CYP1A1 by oltipraz in human Caco-2 cells is aryl hydrocarbon receptor- and calcium-dependent
    • Le Ferrec E, Lagadic-Gossmann D, Rauch C, et al. Transcriptional induction of CYP1A1 by oltipraz in human Caco-2 cells is aryl hydrocarbon receptor- and calcium-dependent. J Biol Chem 2002;277:24780-7.
    • (2002) J Biol Chem , vol.277 , pp. 24780-24787
    • Le Ferrec, E.1    Lagadic-Gossmann, D.2    Rauch, C.3
  • 27
    • 0036156363 scopus 로고    scopus 로고
    • Unique property of some synthetic retinoids: Activation of the aryl hydrocarbon receptor pathway
    • Gambone CJ, Hutcheson JM, Gabriel JL, et al. Unique property of some synthetic retinoids: activation of the aryl hydrocarbon receptor pathway. Mol Pharmacol 2002;61:334-42.
    • (2002) Mol Pharmacol , vol.61 , pp. 334-342
    • Gambone, C.J.1    Hutcheson, J.M.2    Gabriel, J.L.3
  • 28
    • 0037452886 scopus 로고    scopus 로고
    • The spatial targeting and nuclear matrix binding domains of SRm160
    • Wagner S, Chiosea S. Nickerson JA. The spatial targeting and nuclear matrix binding domains of SRm160. Proc Natl Acad Sci U S A 2003;100:3269-74.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 3269-3274
    • Wagner, S.1    Chiosea, S.2    Nickerson, J.A.3
  • 29
    • 0017363296 scopus 로고
    • Characteristics of a microsomal cytochrome P-448-mediated reaction. Etboxyresorufin O-de-ethylation
    • Burke MD, Prough RA, Mayer RT. Characteristics of a microsomal cytochrome P-448-mediated reaction. Etboxyresorufin O-de-ethylation. Drug Metab Dispos 1977;5:1-8.
    • (1977) Drug Metab Dispos , vol.5 , pp. 1-8
    • Burke, M.D.1    Prough, R.A.2    Mayer, R.T.3
  • 30
    • 0019878355 scopus 로고
    • Sequence of UI RNA from Drosophila melanogaster: Implications for UI secondary structure and possible involvement in splicing
    • Mount SM, Steitz JA. Sequence of UI RNA from Drosophila melanogaster: implications for UI secondary structure and possible involvement in splicing. Nucleic Acids Res 1981;9:6351-68.
    • (1981) Nucleic Acids Res , vol.9 , pp. 6351-6368
    • Mount, S.M.1    Steitz, J.A.2
  • 31
    • 0030964105 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: Signals, mechanisms and regulation
    • Nigg EA. Nucleocytoplasmic transport: signals, mechanisms and regulation. Nature 1997;386:779-87.
    • (1997) Nature , vol.386 , pp. 779-787
    • Nigg, E.A.1
  • 32
    • 0030969942 scopus 로고    scopus 로고
    • Protein import into mitochondria
    • Neupert W. Protein import into mitochondria. Annu Rev Biochem 1997;66:863-917.
    • (1997) Annu Rev Biochem , vol.66 , pp. 863-917
    • Neupert, W.1
  • 33
    • 0026069154 scopus 로고
    • Development of hydrophobicity parameters to analyze proteins which bear post- or cotranslational modifications
    • Black SD, Mould DR. Development of hydrophobicity parameters to analyze proteins which bear post- or cotranslational modifications. Anal Biochem 1991;193:72-82.
    • (1991) Anal Biochem , vol.193 , pp. 72-82
    • Black, S.D.1    Mould, D.R.2
  • 34
    • 0036805854 scopus 로고    scopus 로고
    • Molecular modeling of cytochrome P450 1A1: Enzyme-substrate interactions and substrate binding affinities
    • Szklarz GD, Paulsen MD. Molecular modeling of cytochrome P450 1A1: enzyme-substrate interactions and substrate binding affinities. J Biomol Struct Dyn 2002;20:155-62.
    • (2002) J Biomol Struct Dyn , vol.20 , pp. 155-162
    • Szklarz, G.D.1    Paulsen, M.D.2
  • 35
    • 0034969560 scopus 로고    scopus 로고
    • Induction of CYP1A1. The AhR/DRE paradigm: Transcription, receptor regulation, and expanding biological roles
    • Ma Q. Induction of CYP1A1. The AhR/DRE paradigm: transcription, receptor regulation, and expanding biological roles. Curr Drug Metab 2001;2:149-64.
    • (2001) Curr Drug Metab , vol.2 , pp. 149-164
    • Ma, Q.1
  • 36
    • 0030825040 scopus 로고    scopus 로고
    • Cigarette smoke radicals and the role of free radicals in chemical carcinogenicity
    • Pryor WA. Cigarette smoke radicals and the role of free radicals in chemical carcinogenicity. Environ Health Perspect 1997;105:875-82.
    • (1997) Environ Health Perspect , vol.105 , pp. 875-882
    • Pryor, W.A.1
  • 37
    • 0035090669 scopus 로고    scopus 로고
    • Differential metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8- dihydrodiol by human CYP1A1 variants
    • Schwarz D, Kisselev P, Cascorbi I, et al. Differential metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 variants. Carcinogenesis 2001;22:453-9.
    • (2001) Carcinogenesis , vol.22 , pp. 453-459
    • Schwarz, D.1    Kisselev, P.2    Cascorbi, I.3
  • 38
    • 0037062982 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing and proteome expansion in metazoans
    • Maniatis T, Tasic B. Alternative pre-mRNA splicing and proteome expansion in metazoans. Nature 2002;418:236-43.
    • (2002) Nature , vol.418 , pp. 236-243
    • Maniatis, T.1    Tasic, B.2
  • 39
    • 0018617943 scopus 로고
    • Drug metabolism: Speculations on the future
    • Bresnick E. Drug metabolism: speculations on the future. Drug Metab Rev 1979;10:311-3.
    • (1979) Drug Metab Rev , vol.10 , pp. 311-313
    • Bresnick, E.1
  • 40
    • 0030611669 scopus 로고    scopus 로고
    • 2-terminal-processed microsomal protein to mitochondria: A novel pathway for the biogenesis of hepatic mitochondrial P450MT2
    • 2-terminal-processed microsomal protein to mitochondria: a novel pathway for the biogenesis of hepatic mitochondrial P450MT2. J Cell Biol 1997;139:589-99.
    • (1997) J Cell Biol , vol.139 , pp. 589-599
    • Addya, S.1    Anandatheertbavarada, H.K.2    Biswas, G.3
  • 41
    • 0020019303 scopus 로고
    • The Ah locus, a multigene family necessary for survival in a chemically adverse environment: Comparison with the immune system
    • Nebert DW, Negisbi M, Lang MA, et al. The Ah locus, a multigene family necessary for survival in a chemically adverse environment: comparison with the immune system. Adv Genet 1982;21:1-52.
    • (1982) Adv Genet , vol.21 , pp. 1-52
    • Nebert, D.W.1    Negisbi, M.2    Lang, M.A.3
  • 42
    • 0034667416 scopus 로고    scopus 로고
    • The relationship between benzo[a]pyrene-induced mutagenesis and carcinogenesis in repair-deficient Cockayne syndrome group B mice
    • Wijnhoven SW, Kool HJ, van Oostrom CT, et al. The relationship between benzo[a]pyrene-induced mutagenesis and carcinogenesis in repair-deficient Cockayne syndrome group B mice. Cancer Res 2000;60:5681-7.
    • (2000) Cancer Res , vol.60 , pp. 5681-5687
    • Wijnhoven, S.W.1    Kool, H.J.2    Van Oostrom, C.T.3
  • 43
    • 2442675553 scopus 로고    scopus 로고
    • Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway
    • Chen SY, Lin JR, Darbha R, et al. Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway. Cancer Res 2004;64:3617-23.
    • (2004) Cancer Res , vol.64 , pp. 3617-3623
    • Chen, S.Y.1    Lin, J.R.2    Darbha, R.3
  • 44
    • 0036606681 scopus 로고    scopus 로고
    • Polymorphisms of the estrogen-metabolizing genes CYP17 and catechol-O-methyltransferase and risk of epithelial ovarian cancer
    • Garner El, Stokes EE, Berkowitz RS. et al. Polymorphisms of the estrogen-metabolizing genes CYP17 and catechol-O-methyltransferase and risk of epithelial ovarian cancer. Cancer Res 2002;62:3058-62.
    • (2002) Cancer Res , vol.62 , pp. 3058-3062
    • Garner, El.1    Stokes, E.E.2    Berkowitz, R.S.3
  • 45
    • 0031752385 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase and breast cancer risk
    • Millikan RC, Pittman GS, Tse CK, et al. Catechol-O-methyltransferase and breast cancer risk. Carcinogenesis 1998;19:1943-7.
    • (1998) Carcinogenesis , vol.19 , pp. 1943-1947
    • Millikan, R.C.1    Pittman, G.S.2    Tse, C.K.3
  • 46
    • 0034068827 scopus 로고    scopus 로고
    • Molecular epidemiology of breast cancer: Genetic variation in steroid hormone metabolism
    • Kristensen VN, Borresen-Dale AL. Molecular epidemiology of breast cancer: genetic variation in steroid hormone metabolism. Mutat Res 2000;462:323-33.
    • (2000) Mutat Res , vol.462 , pp. 323-333
    • Kristensen, V.N.1    Borresen-Dale, A.L.2
  • 47
    • 4644229681 scopus 로고    scopus 로고
    • In vitro model of mammary estrogen metabolism: Structural and kinetic differences between catechol estrogens 2- and 4-hydroxyestradiol
    • Dawling S, Hachey DL, Roodi N, et al. In vitro model of mammary estrogen metabolism: structural and kinetic differences between catechol estrogens 2- and 4-hydroxyestradiol. Chem Res Toxicol 2004;17:1258-64.
    • (2004) Chem Res Toxicol , vol.17 , pp. 1258-1264
    • Dawling, S.1    Hachey, D.L.2    Roodi, N.3
  • 48
    • 0035123775 scopus 로고    scopus 로고
    • Precursor lesions of ovarian epithelial malignancy
    • Fecley KM. Wells M. Precursor lesions of ovarian epithelial malignancy. Histopathology 2001;38:87-95.
    • (2001) Histopathology , vol.38 , pp. 87-95
    • Fecley, K.M.1    Wells, M.2
  • 49
    • 0042315387 scopus 로고    scopus 로고
    • Characterization of the oxidative metabolites of 17β-estradiol and estrone formed by 15 selectively expressed human cytochrome P450 isoforms
    • Lee AJ, Cai MX, Thomas PE, et al. Characterization of the oxidative metabolites of 17β-estradiol and estrone formed by 15 selectively expressed human cytochrome P450 isoforms. Endocrinology 2003;144:3382-98.
    • (2003) Endocrinology , vol.144 , pp. 3382-3398
    • Lee, A.J.1    Cai, M.X.2    Thomas, P.E.3


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