The effect of liver cirrhosis on the regulation and expression of drug metabolizing enzymes

Current Drug Metabolism

Volumn 5, Issue 2, 2004, Pages 157-167

  Elbekai, Reem H ^a   Korashy, Hesham M ^a   El Kadi, Ayman O S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Cirrhosis; Cytochrome P450; Drug metabolizing enzymes; Liver diseases

Indexed keywords

ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; AMPRENAVIR; ATOMOXETINE; BOSENTAN; BUDESONIDE; CLARITHROMYCIN; CLOPIDOGREL; CYTOCHROME P450 1A; CYTOCHROME P450 2A; CYTOCHROME P450 2A6; CYTOCHROME P450 2B; CYTOCHROME P450 2C; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; DICLOFENAC; DONEPEZIL; DRUG METABOLIZING ENZYME; EVEROLIMUS; FLUOROURACIL; HEME OXYGENASE; LAMOTRIGINE; NATEGLINIDE; OMAPATRILAT; OMEPRAZOLE; QUETIAPINE; SULFATASE; TACROLIMUS; UNINDEXED DRUG; XANTHINE OXIDASE;

DISEASE SEVERITY; DOSE RESPONSE; DRUG CLEARANCE; DRUG DISPOSITION; DRUG GLUCURONIDATION; DRUG MECHANISM; DRUG METABOLISM; DRUG SULFATION; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; LIVER CIRRHOSIS; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; REVIEW;

CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; ISOENZYMES; LIVER; LIVER CIRRHOSIS; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS;

EID: 1942421303     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389200043489054     Document Type: Review

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