An unusual TOM20/TOM22 bypass mechanism for the mitochondrial targeting of cytochrome P450 proteins containing n-terminal chimeric signals

Journal of Biological Chemistry

Volumn 283, Issue 28, 2008, Pages 19769-19780

  Anandatheerthavarada, Hindupur K ^a   Sepuri, Naresh Babu V ^a   Biswas, Gopa ^a   Avadhani, Narayan G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AMINO ACIDS; FLOW INTERACTIONS; MITOCHONDRIA; OPTICAL PROPERTIES; ORGANIC ACIDS; PORT TERMINALS; PROTEINS;

CYTOSOL; CYTOSOLIC; DO-MAINS; ENDOPLASMIC RETICULUM; MITOCHONDRIAL IMPORTS; MITOCHONDRIAL TRANSLOCATIONS; OUTER MEMBRANES; SEQUENTIAL INTERACTIONS; TRANSLOCASES; UNDERLYING MECHANISMS; UNIMODAL;

ABERRATIONS;

AMINO ACID; CHIMERIC PROTEIN; CHOLESTANETRIOL 26 MONOOXYGENASE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 2B1; CYTOCHROME P450 2E1; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; OUTER MEMBRANE PROTEIN; TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20; TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 22; TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 40; TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 70; UNCLASSIFIED DRUG; CARRIER PROTEIN; CELL RECEPTOR; MITOCHONDRIAL PROTEIN; SIGNAL PEPTIDE; TOM20 PROTEIN, RAT; TOMM22 PROTEIN, RAT;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSOL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PROTEIN TRANSPORT; RAT; ANIMAL; CYTOPLASM; GENETICS; LIVER MITOCHONDRION; METABOLISM; PHYSIOLOGY; RABBIT; SACCHAROMYCES CEREVISIAE;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; CYTOPLASM; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIA, LIVER; MITOCHONDRIAL PROTEINS; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; RABBITS; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SACCHAROMYCES CEREVISIAE;

EID: 50349099993     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801464200     Document Type: Article

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