Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α)

PLoS ONE

Volumn 6, Issue 1, 2011, Pages

  Thalhammer, Armin ^b   Bencokova, Zuzana ^c   Poole, Rachel ^c   Loenarz, Christoph ^b   Adam, Julie ^a   O'Flaherty, Linda ^a   Schödel, Johannes ^a   Mole, David ^a   Giaslakiotis, Konstantinos ^d   Schofield, Christopher J ^b   Hammond, Ester M ^c   Ratcliffe, Peter J ^a   Pollard, Patrick J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MEMBRANE PROTEIN; OXYGENASE; PROTEIN ALKB HOMOLOGUE 5; UNCLASSIFIED DRUG; ALKBH5 PROTEIN, HUMAN; NUCLEAR PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DECARBOXYLATION; DNA METHYLATION; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE LOCUS; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PROTEIN METABOLISM; PROTEIN PURIFICATION; SEQUENCE HOMOLOGY; UPREGULATION; ANOXIA; CELL LINE; GENETICS; METABOLISM; PHYSIOLOGY; TRANSCRIPTION INITIATION;

ESCHERICHIA COLI;

ANOXIA; CELL LINE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KETOGLUTARIC ACIDS; NUCLEAR PROTEINS; OXYGENASES; TRANSCRIPTIONAL ACTIVATION;

EID: 79251588745     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016210     Document Type: Article

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