Human AlkB homolog ABH8 is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival

Molecular and Cellular Biology

Volumn 30, Issue 10, 2010, Pages 2449-2459

  Fu, Dragony ^a,b   Brophy, Jennifer A N ^a   Chan, Clement T Y ^a,b   Atmore, Kyle A ^a   Begley, Ulrike ^c   Paules, Richard S ^d   Dedon, Peter C ^a,b   Begley, Thomas J ^c   Samson, Leona D ^a,b  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLCARBOXYMETHYLURIDINE; ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8; BLEOMYCIN; DNA; LENTIVIRUS VECTOR; MESSENGER RNA; SHORT HAIRPIN RNA; TRANSFER RNA; TRANSFER RNA METHYLTRANSFERASE; UNCLASSIFIED DRUG; URIDINE; URIDINE DERIVATIVE;

ALKBH 8 GENE; ARTICLE; CELL CULTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; GENE; GENE EXPRESSION; GENE FUNCTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN RNA BINDING; QUADRUPOLE MASS SPECTROMETRY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA INTERFERENCE; RNA METHYLATION;

ANIMALS; CELL LINE; DNA DAMAGE; HUMANS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; PHYLOGENY; RNA, TRANSFER; TRNA METHYLTRANSFERASES; URIDINE;

MAMMALIA;

EID: 77951981033     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01604-09     Document Type: Article

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