메뉴 건너뛰기




Volumn 343, Issue 1, 2011, Pages 5-12

Intestinal epithelial cells and their role in innate mucosal immunity

Author keywords

Epithelial cells; Human; Inflammation; Innate immunity; Intestine; Microbes

Indexed keywords

ALPHA DEFENSIN; BETA DEFENSIN 1; BETA DEFENSIN 2; BETA DEFENSIN 3; CASPASE; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; CATHELICIDIN; DEFENSIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTESTINAL TREFOIL FACTOR; LYSOZYME; MITOGEN ACTIVATED PROTEIN KINASE; MUCIN 2; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA;

EID: 79151485800     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00441-010-1082-5     Document Type: Review
Times cited : (64)

References (88)
  • 1
    • 0035424901 scopus 로고    scopus 로고
    • Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide
    • 1:CAS:528:DC%2BD3MXls1WrsL8%3D 11466383
    • MT Abreu P Vora E Faure LS Thomas ET Arnold M Arditi 2001 Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide J Immunol 167 1609 1616 1:CAS:528:DC%2BD3MXls1WrsL8%3D 11466383
    • (2001) J Immunol , vol.167 , pp. 1609-1616
    • Abreu, M.T.1    Vora, P.2    Faure, E.3    Thomas, L.S.4    Arnold, E.T.5    Arditi, M.6
  • 2
    • 0029912970 scopus 로고    scopus 로고
    • Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues
    • DOI 10.1083/jcb.133.1.43
    • Y Ando-Akatsuka M Saitou T Hirase M Kishi A Sakakibara M Itoh S Yonemura M Furuse S Tsukita 1996 Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues J Cell Biol 133 43 47 1:CAS:528:DyaK28XitVCht7c%3D 10.1083/jcb.133.1.43 8601611 (Pubitemid 26107094)
    • (1996) Journal of Cell Biology , vol.133 , Issue.1 , pp. 43-48
    • Ando-Akatsuka, Y.1    Saitou, M.2    Hirase, T.3    Kishi, M.4    Sakakibara, A.5    Itoh, M.6    Yonemura, S.7    Furuse, M.8    Tsukita, S.9
  • 3
    • 0025936556 scopus 로고
    • The polymeric immunoglobulin receptor. A model protein to study transcytosis
    • 1:CAS:528:DyaK3MXks12ls7s%3D 10.1172/JCI115211 2040683
    • G Apodaca M Bomsel J Arden PP Breitfeld K Tang KE Mostov 1991 The polymeric immunoglobulin receptor. A model protein to study transcytosis J Clin Invest 87 1877 1882 1:CAS:528:DyaK3MXks12ls7s%3D 10.1172/JCI115211 2040683
    • (1991) J Clin Invest , vol.87 , pp. 1877-1882
    • Apodaca, G.1    Bomsel, M.2    Arden, J.3    Breitfeld, P.P.4    Tang, K.5    Mostov, K.E.6
  • 5
    • 22244465576 scopus 로고    scopus 로고
    • Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-ΚB activation in muramyl dipeptide recognition
    • DOI 10.1083/jcb.200502153
    • N Barnich JE Aguirre HC Reinecker R Xavier DK Podolsky 2005 Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition J Cell Biol 170 21 26 1:CAS:528:DC%2BD2MXlvFCgu7Y%3D 10.1083/jcb.200502153 15998797 (Pubitemid 40994092)
    • (2005) Journal of Cell Biology , vol.170 , Issue.1 , pp. 21-26
    • Barnich, N.1    Aguirre, J.E.2    Reinecker, H.-C.3    Xavier, R.4    Podolsky, D.K.5
  • 6
    • 0028981702 scopus 로고
    • HBD-1: A novel beta-defensin from human plasma
    • 1:CAS:528:DyaK2MXntFCrs7w%3D 10.1016/0014-5793(95)00687-5 7628632
    • KW Bensch M Raida HJ Magert P Schulz-Knappe WG Forssmann 1995 hBD-1: a novel beta-defensin from human plasma FEBS Lett 368 331 335 1:CAS:528: DyaK2MXntFCrs7w%3D 10.1016/0014-5793(95)00687-5 7628632
    • (1995) FEBS Lett , vol.368 , pp. 331-335
    • Bensch, K.W.1    Raida, M.2    Magert, H.J.3    Schulz-Knappe, P.4    Forssmann, W.G.5
  • 8
    • 77957047689 scopus 로고    scopus 로고
    • Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum
    • 1:CAS:528:DC%2BC3cXhtVOgsbzE 10.1073/pnas.1003363107 20679225
    • A Biswas YJ Liu L Hao A Mizoguchi NH Salzman CL Bevins KS Kobayashi 2010 Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum Proc Natl Acad Sci USA 107 14739 14744 1:CAS:528:DC%2BC3cXhtVOgsbzE 10.1073/pnas.1003363107 20679225
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 14739-14744
    • Biswas, A.1    Liu, Y.J.2    Hao, L.3    Mizoguchi, A.4    Salzman, N.H.5    Bevins, C.L.6    Kobayashi, K.S.7
  • 10
    • 0034445697 scopus 로고    scopus 로고
    • Differential alteration in intestinal epithelial cell expression of Toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
    • DOI 10.1128/IAI.68.12.7010-7017.2000
    • E Cario DK Podolsky 2000 Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease Infect Immun 68 7010 7017 1:CAS:528:DC%2BD3MXjslCku7w%3D 10.1128/IAI.68.12.7010-7017.2000 11083826 (Pubitemid 32463415)
    • (2000) Infection and Immunity , vol.68 , Issue.12 , pp. 7010-7017
    • Cario, E.1    Podolsky, D.K.2
  • 11
    • 0036144233 scopus 로고    scopus 로고
    • Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium
    • 1:CAS:528:DC%2BD38XnvFehtA%3D%3D 11786410
    • E Cario D Brown M McKee K Lynch-Devaney G Gerken DK Podolsky 2002 Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium Am J Pathol 160 165 173 1:CAS:528: DC%2BD38XnvFehtA%3D%3D 11786410
    • (2002) Am J Pathol , vol.160 , pp. 165-173
    • Cario, E.1    Brown, D.2    McKee, M.3    Lynch-Devaney, K.4    Gerken, G.5    Podolsky, D.K.6
  • 12
    • 33646858115 scopus 로고    scopus 로고
    • The oligopeptide transporter hPepT1: Gateway to the innate immune response
    • 1:CAS:528:DC%2BD28Xkslemu7c%3D 10.1038/labinvest.3700413 16652110
    • L Charrier D Merlin 2006 The oligopeptide transporter hPepT1: gateway to the innate immune response Lab Invest 86 538 546 1:CAS:528:DC%2BD28Xkslemu7c%3D 10.1038/labinvest.3700413 16652110
    • (2006) Lab Invest , vol.86 , pp. 538-546
    • Charrier, L.1    Merlin, D.2
  • 13
    • 0030448437 scopus 로고    scopus 로고
    • Requirement of CDC42 for Salmonella-induced cytoskeletal and nuclear responses
    • DOI 10.1126/science.274.5295.2115
    • LM Chen S Hobbie JE Galan 1996 Requirement of CDC42 for Salmonella-induced cytoskeletal and nuclear responses Science 274 2115 2118 1:CAS:528:DyaK2sXjt1Ki 10.1126/science.274.5295.2115 8953049 (Pubitemid 27020711)
    • (1996) Science , vol.274 , Issue.5295 , pp. 2115-2118
    • Chen, L.-M.1    Hobbie, S.2    Galan, J.E.3
  • 14
    • 44349124113 scopus 로고    scopus 로고
    • The genetics and immunopathogenesis of inflammatory bowel disease
    • DOI 10.1038/nri2340, PII NRI2340
    • JH Cho 2008 The genetics and immunopathogenesis of inflammatory bowel disease Nat Rev Immunol 8 458 466 1:CAS:528:DC%2BD1cXmt1Ojt7o%3D 10.1038/nri2340 18500230 (Pubitemid 351733422)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.6 , pp. 458-466
    • Cho, J.H.1
  • 15
    • 67651231051 scopus 로고    scopus 로고
    • Intestinal mucus barrier in normal and inflamed colon
    • 10.1097/MPG.0b013e3181a117ea 19300126
    • ES Corazziari 2009 Intestinal mucus barrier in normal and inflamed colon J Pediatr Gastroenterol Nutr 48 Suppl 2 S54 S55 10.1097/MPG.0b013e3181a117ea 19300126
    • (2009) J Pediatr Gastroenterol Nutr , vol.48 , Issue.SUPPL. 2
    • Corazziari, E.S.1
  • 16
    • 0034110489 scopus 로고    scopus 로고
    • Characterization of binding of Candida albicans to small intestinal mucin and its role in adherence to mucosal epithelial cells
    • DOI 10.1128/IAI.68.6.3172-3179.2000
    • L de Repentigny F Aumont K Bernard P Belhumeur 2000 Characterization of binding of Candida albicans to small intestinal mucin and its role in adherence to mucosal epithelial cells Infect Immun 68 3172 3179 10.1128/IAI.68.6.3172- 3179.2000 10816460 (Pubitemid 30340406)
    • (2000) Infection and Immunity , vol.68 , Issue.6 , pp. 3172-3179
    • De Repentigny, L.1    Aumont, F.2    Bernard, K.3    Belhumeur, P.4
  • 17
    • 29144521244 scopus 로고    scopus 로고
    • Human antimicrobial peptides: Defensins, cathelicidins and histatins
    • DOI 10.1007/s10529-005-0936-5
    • K De Smet R Contreras 2005 Human antimicrobial peptides: defensins, cathelicidins and histatins Biotechnol Lett 27 1337 1347 10.1007/s10529-005- 0936-5 16215847 (Pubitemid 41805626)
    • (2005) Biotechnology Letters , vol.27 , Issue.18 , pp. 1337-1347
    • De Smet, K.1    Contreras, R.2
  • 18
    • 0032168228 scopus 로고    scopus 로고
    • β-defensins: Endogenous antibiotics of the innate host defense response
    • DOI 10.1006/clin.1998.4587
    • G Diamond CL Bevins 1998 Beta-defensins: endogenous antibiotics of the innate host defense response Clin Immunol Immunopathol 88 221 225 1:CAS:528:DyaK1cXmsVCmu7w%3D 10.1006/clin.1998.4587 9743607 (Pubitemid 28436242)
    • (1998) Clinical Immunology and Immunopathology , vol.88 , Issue.3 , pp. 221-225
    • Diamond, G.1    Bevins, C.L.2
  • 19
    • 0029586031 scopus 로고
    • Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)
    • 1:STN:280:DyaK287ivVWgsw%3D%3D 10.1111/j.1365-2249.1995.tb03836.x 8536356
    • R Duchmann I Kaiser E Hermann W Mayet K Ewe KH Meyer zum Buschenfelde 1995 Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD) Clin Exp Immunol 102 448 455 1:STN:280:DyaK287ivVWgsw%3D%3D 10.1111/j.1365-2249.1995.tb03836.x 8536356
    • (1995) Clin Exp Immunol , vol.102 , pp. 448-455
    • Duchmann, R.1    Kaiser, I.2    Hermann, E.3    Mayet, W.4    Ewe, K.5    Meyer Zum Buschenfelde, K.H.6
  • 20
    • 34248397191 scopus 로고    scopus 로고
    • Surface expression of toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA
    • DOI 10.1128/IAI.01662-06
    • JB Ewaschuk JL Backer TA Churchill F Obermeier DO Krause KL Madsen 2007 Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA Infect Immun 75 2572 2579 1:CAS:528:DC%2BD2sXlsV2msbs%3D 10.1128/IAI.01662-06 17325049 (Pubitemid 46744349)
    • (2007) Infection and Immunity , vol.75 , Issue.5 , pp. 2572-2579
    • Ewaschuk, J.B.1    Backer, J.L.2    Churchill, T.A.3    Obermeier, F.4    Krause, D.O.5    Madsen, K.L.6
  • 21
    • 0032491391 scopus 로고    scopus 로고
    • The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton
    • DOI 10.1074/jbc.273.45.29745
    • AS Fanning BJ Jameson LA Jesaitis JM Anderson 1998 The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton J Biol Chem 273 29745 29753 1:CAS:528:DyaK1cXntlKqurw%3D 10.1074/jbc.273.45.29745 9792688 (Pubitemid 28509986)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.45 , pp. 29745-29753
    • Fanning, A.S.1    Jameson, B.J.2    Jesaitis, L.A.3    Anderson, J.M.4
  • 22
    • 0034728821 scopus 로고    scopus 로고
    • Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease
    • 1:CAS:528:DC%2BD3cXjt1alt7c%3D 10.1016/S0140-6736(00)02169-3 10801176
    • A Fasano T Not W Wang S Uzzau I Berti A Tommasini SE Goldblum 2000 Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease Lancet 355 1518 1519 1:CAS:528: DC%2BD3cXjt1alt7c%3D 10.1016/S0140-6736(00)02169-3 10801176
    • (2000) Lancet , vol.355 , pp. 1518-1519
    • Fasano, A.1    Not, T.2    Wang, W.3    Uzzau, S.4    Berti, I.5    Tommasini, A.6    Goldblum, S.E.7
  • 23
    • 0033739624 scopus 로고    scopus 로고
    • An essential amino acid induces epithelial beta-defensin expression
    • 1:CAS:528:DC%2BD3cXotFyntr8%3D 10.1073/pnas.220424597 11058160
    • P Fehlbaum M Rao M Zasloff GM Anderson 2000 An essential amino acid induces epithelial beta-defensin expression Proc Natl Acad Sci USA 97 12723 12728 1:CAS:528:DC%2BD3cXotFyntr8%3D 10.1073/pnas.220424597 11058160
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12723-12728
    • Fehlbaum, P.1    Rao, M.2    Zasloff, M.3    Anderson, G.M.4
  • 24
    • 0000646464 scopus 로고
    • On a remarkable bacteriolytic element found in tissues and secretions
    • 10.1098/rspb.1922.0023
    • A Fleming 1922 On a remarkable bacteriolytic element found in tissues and secretions Proc R Soc Lond [Biol] B39 306 317 10.1098/rspb.1922.0023
    • (1922) Proc R Soc Lond [Biol] , vol.B39 , pp. 306-317
    • Fleming, A.1
  • 25
    • 0027744129 scopus 로고
    • Occludin: A novel integral membrane protein localizing at tight junctions
    • DOI 10.1083/jcb.123.6.1777
    • M Furuse T Hirase M Itoh A Nagafuchi S Yonemura S Tsukita 1993 Occludin: a novel integral membrane protein localizing at tight junctions J Cell Biol 123 1777 1788 1:CAS:528:DyaK2cXisFynsQ%3D%3D 10.1083/jcb.123.6.1777 8276896 (Pubitemid 24012933)
    • (1993) Journal of Cell Biology , vol.123 , Issue.6 II , pp. 1777-1788
    • Furuse, M.1    Hirase, T.2    Itoh, M.3    Nagafuchi, A.4    Yonemura, S.5    Tsukita, S.6    Tsukita, S.7
  • 26
    • 0028110309 scopus 로고
    • Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions
    • DOI 10.1083/jcb.127.6.1617
    • M Furuse M Itoh T Hirase A Nagafuchi S Yonemura S Tsukita 1994 Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions J Cell Biol 127 1617 1626 1:CAS:528:DyaK2cXmvFOmu7g%3D 10.1083/jcb.127.6.1617 7798316 (Pubitemid 24380900)
    • (1994) Journal of Cell Biology , vol.127 , Issue.6 I , pp. 1617-1626
    • Furuse, M.1    Itoh, M.2    Hirase, T.3    Nagaftichi, A.4    Yonemura, S.5    Tsukita, S.6    Tsukita, S.7
  • 27
    • 0032577975 scopus 로고    scopus 로고
    • Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
    • DOI 10.1083/jcb.141.7.1539
    • M Furuse K Fujita T Hiiragi K Fujimoto S Tsukita 1998 Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin J Cell Biol 141 1539 1550 1:CAS:528:DyaK1cXksFWjur8%3D 10.1083/jcb.141.7.1539 9647647 (Pubitemid 28309169)
    • (1998) Journal of Cell Biology , vol.141 , Issue.7 , pp. 1539-1550
    • Furuse, M.1    Fujita, K.2    Hiiragi, T.3    Fujimoto, K.4    Tsukita, S.5
  • 29
    • 0033569682 scopus 로고    scopus 로고
    • Defensins and host defense
    • 1:CAS:528:DyaK1MXmvVOhsLg%3D 10.1126/science.286.5439.420 10577203
    • T Ganz 1999 Defensins and host defense Science 286 420 421 1:CAS:528:DyaK1MXmvVOhsLg%3D 10.1126/science.286.5439.420 10577203
    • (1999) Science , vol.286 , pp. 420-421
    • Ganz, T.1
  • 30
    • 0001475281 scopus 로고    scopus 로고
    • Identification of a novel, multifunctional β-defensin (human β-defensin 3) with specific antimicrobial activity: Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction
    • DOI 10.1007/s004410100433
    • JR Garcia F Jaumann S Schulz A Krause J Rodriguez-Jimenez U Forssmann K Adermann E Kluver C Vogelmeier D Becker R Hedrich WG Forssmann R Bals 2001 Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction Cell Tissue Res 306 257 264 1:CAS:528:DC%2BD3MXotVaisbs%3D 10.1007/s004410100433 11702237 (Pubitemid 32972384)
    • (2001) Cell and Tissue Research , vol.306 , Issue.2 , pp. 257-264
    • Garcia, J.-R.C.1    Jaumann, F.2    Schulz, S.3    Krause, A.4    Rodriguez-Jimenez, J.5    Forssmann, U.6    Adermann, K.7    Kluver, E.8    Vogelmeier, C.9    Becker, D.10    Hedrich, R.11    Forssmann, W.-G.12    Bals, R.13
  • 31
    • 0035881675 scopus 로고    scopus 로고
    • Cutting edge: Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
    • 1:CAS:528:DC%2BD3MXlvFeqt7Y%3D 11489966
    • AT Gewirtz TA Navas S Lyons PJ Godowski JL Madara 2001 Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression J Immunol 167 1882 1885 1:CAS:528: DC%2BD3MXlvFeqt7Y%3D 11489966
    • (2001) J Immunol , vol.167 , pp. 1882-1885
    • Gewirtz, A.T.1    Navas, T.A.2    Lyons, S.3    Godowski, P.J.4    Madara, J.L.5
  • 33
    • 0025073818 scopus 로고
    • Involvement of M cells in the bacterial invasion of Peyer's patches: A common mechanism shared by Yersinia enterocolitica and other enteroinvasive bacteria
    • 1:STN:280:DyaK3M%2Fgsleqtg%3D%3D 10.1136/gut.31.9.1011 2210445
    • A Grutzkau C Hanski H Hahn EO Riecken 1990 Involvement of M cells in the bacterial invasion of Peyer's patches: a common mechanism shared by Yersinia enterocolitica and other enteroinvasive bacteria Gut 31 1011 1015 1:STN:280:DyaK3M%2Fgsleqtg%3D%3D 10.1136/gut.31.9.1011 2210445
    • (1990) Gut , vol.31 , pp. 1011-1015
    • Grutzkau, A.1    Hanski, C.2    Hahn, H.3    Riecken, E.O.4
  • 34
    • 0036151109 scopus 로고    scopus 로고
    • Cell differentiation is a key determinant of cathelicidin LL-37/human cationic antimicrobial protein 18 expression by human colon epithelium
    • DOI 10.1128/IAI.70.2.953-963.2002
    • K Hase L Eckmann JD Leopard N Varki MF Kagnoff 2002 Cell differentiation is a key determinant of cathelicidin LL-37/human cationic antimicrobial protein 18 expression by human colon epithelium Infect Immun 70 953 963 1:CAS:528:DC%2BD38XoslyhtA%3D%3D 10.1128/IAI.70.2.953-963.2002 11796631 (Pubitemid 34083859)
    • (2002) Infection and Immunity , vol.70 , Issue.2 , pp. 953-963
    • Hase, K.1    Eckmann, L.2    Leopard, J.D.3    Varki, N.4    Kagnoff, M.F.5
  • 35
    • 10744224946 scopus 로고    scopus 로고
    • Expression of LL-37 by Human Gastric Epithelial Cells as a Potential Host Defense Mechanism Against Helicobacter pylori
    • DOI 10.1053/j.gastro.2003.08.028
    • K Hase M Murakami M Iimura SP Cole Y Horibe T Ohtake M Obonyo RL Gallo L Eckmann MF Kagnoff 2003 Expression of LL-37 by human gastric epithelial cells as a potential host defense mechanism against Helicobacter pylori Gastroenterology 125 1613 1625 1:CAS:528:DC%2BD2cXhtVOrsQ%3D%3D 10.1053/j.gastro.2003.08.028 14724813 (Pubitemid 37500425)
    • (2003) Gastroenterology , vol.125 , Issue.6 , pp. 1613-1625
    • Hase, K.1    Murakami, M.2    Iimura, M.3    Cole, S.P.4    Horibe, Y.5    Ohtake, T.6    Obonyo, M.7    Gallo, R.L.8    Eckmann, L.9    Kagnoff, M.F.10
  • 37
    • 0037380969 scopus 로고    scopus 로고
    • CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells
    • DOI 10.1053/gast.2003.50153
    • T Hisamatsu M Suzuki HC Reinecker WJ Nadeau BA McCormick DK Podolsky 2003 CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells Gastroenterology 124 993 1000 1:CAS:528:DC%2BD3sXjsFOju7g%3D 10.1053/gast.2003.50153 12671896 (Pubitemid 36389802)
    • (2003) Gastroenterology , vol.124 , Issue.4 , pp. 993-1000
    • Hisamatsu, T.1    Suzuki, M.2    Reinecker, H.-C.3    Nadeau, W.J.4    McCormick, B.A.5    Podolsky, D.K.6
  • 38
    • 0029118304 scopus 로고
    • Bordetella bronchiseptica dermonecrotizing toxin stimulates assembly of actin stress fibers and focal adhesions by modifying the small GTP-binding protein rho
    • 1:CAS:528:DyaK2MXoslWnu7w%3D 7593285
    • Y Horiguchi T Senda N Sugimoto J Katahira M Matsuda 1995 Bordetella bronchiseptica dermonecrotizing toxin stimulates assembly of actin stress fibers and focal adhesions by modifying the small GTP-binding protein rho J Cell Sci 108 3243 3251 1:CAS:528:DyaK2MXoslWnu7w%3D 7593285
    • (1995) J Cell Sci , vol.108 , pp. 3243-3251
    • Horiguchi, Y.1    Senda, T.2    Sugimoto, N.3    Katahira, J.4    Matsuda, M.5
  • 39
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
    • 1:CAS:528:DyaK1MXitFGqsL4%3D 10201887
    • K Hoshino O Takeuchi T Kawai H Sanjo T Ogawa Y Takeda K Takeda S Akira 1999 Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product J Immunol 162 3749 3752 1:CAS:528:DyaK1MXitFGqsL4%3D 10201887
    • (1999) J Immunol , vol.162 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3    Sanjo, H.4    Ogawa, T.5    Takeda, Y.6    Takeda, K.7    Akira, S.8
  • 40
    • 17044404692 scopus 로고    scopus 로고
    • Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens
    • 1:CAS:528:DC%2BD2MXivFKiurY%3D 15814717
    • M Iimura RL Gallo K Hase Y Miyamoto L Eckmann MF Kagnoff 2005 Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens J Immunol 174 4901 4907 1:CAS:528:DC%2BD2MXivFKiurY%3D 15814717
    • (2005) J Immunol , vol.174 , pp. 4901-4907
    • Iimura, M.1    Gallo, R.L.2    Hase, K.3    Miyamoto, Y.4    Eckmann, L.5    Kagnoff, M.F.6
  • 41
    • 0035126317 scopus 로고    scopus 로고
    • Downregulation of bactericidal peptides in enteric infections: A novel immune escape mechanism with bacterial DNA as a potential regulator
    • DOI 10.1038/84627
    • D Islam L Bandholtz J Nilsson H Wigzell B Christensson B Agerberth G Gudmundsson 2001 Downregulation of bactericidal peptides in enteric infections: a novel immune escape mechanism with bacterial DNA as a potential regulator Nat Med 7 180 185 1:CAS:528:DC%2BD3MXhtVyltLs%3D 10.1038/84627 11175848 (Pubitemid 32148484)
    • (2001) Nature Medicine , vol.7 , Issue.2 , pp. 180-185
    • Islam, D.1    Bandholtz, L.2    Nilsson, J.3    Wigzell, H.4    Christensson, B.5    Agerberth, B.6    Gudmundsson, G.H.7
  • 42
    • 0033552629 scopus 로고    scopus 로고
    • Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins
    • DOI 10.1083/jcb.147.6.1351
    • M Itoh M Furuse K Morita K Kubota M Saitou S Tsukita 1999 Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins J Cell Biol 147 1351 1363 1:CAS:528:DyaK1MXotVGqurc%3D 10.1083/jcb.147.6.1351 10601346 (Pubitemid 30012818)
    • (1999) Journal of Cell Biology , vol.147 , Issue.6 , pp. 1351-1363
    • Itoh, M.1    Furuse, M.2    Morita, K.3    Kubota, K.4    Saitou, M.5    Tsukita, S.6
  • 44
    • 0028214086 scopus 로고
    • Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches
    • DOI 10.1084/jem.180.1.15
    • BD Jones N Ghori S Falkow 1994 Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches J Exp Med 180 15 23 1:STN:280:DyaK2c3nsFeltQ%3D%3D 10.1084/jem.180.1.15 8006579 (Pubitemid 24181051)
    • (1994) Journal of Experimental Medicine , vol.180 , Issue.1 , pp. 15-23
    • Jones, B.D.1    Ghori, N.2    Falkow, S.3
  • 45
    • 33646589718 scopus 로고    scopus 로고
    • Vangl1 protein acts as a downstream effector of intestinal trefoil factor (ITF)/TFF3 signaling and regulates wound healing of intestinal epithelium
    • DOI 10.1074/jbc.M512905200
    • J Kalabis I Rosenberg DK Podolsky 2006 Vangl1 protein acts as a downstream effector of intestinal trefoil factor (ITF)/TFF3 signaling and regulates wound healing of intestinal epithelium J Biol Chem 281 6434 6441 1:CAS:528:DC%2BD28XhvFOgsrw%3D 10.1074/jbc.M512905200 16410243 (Pubitemid 43847575)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.10 , pp. 6434-6441
    • Kalabis, J.1    Rosenberg, I.2    Podolsky, D.K.3
  • 46
    • 33645960706 scopus 로고    scopus 로고
    • TLR signaling
    • 1:CAS:528:DC%2BD28XjsFWisbo%3D 10.1038/sj.cdd.4401850 16410796
    • T Kawai S Akira 2006 TLR signaling Cell Death Differ 13 816 825 1:CAS:528:DC%2BD28XjsFWisbo%3D 10.1038/sj.cdd.4401850 16410796
    • (2006) Cell Death Differ , vol.13 , pp. 816-825
    • Kawai, T.1    Akira, S.2
  • 47
    • 33751549487 scopus 로고    scopus 로고
    • Paneth cells: Leukocyte-like mediators of innate immunity in the intestine
    • DOI 10.1189/jlb.1005556
    • S Keshav 2006 Paneth cells: leukocyte-like mediators of innate immunity in the intestine J Leukoc Biol 80 500 508 1:CAS:528:DC%2BD28XpsVOmsrY%3D 10.1189/jlb.1005556 16793911 (Pubitemid 44835783)
    • (2006) Journal of Leukocyte Biology , vol.80 , Issue.3 , pp. 500-508
    • Keshav, S.1
  • 48
    • 0029133784 scopus 로고
    • Trefoil peptide protection of intestinal epithelial barrier function: Cooperative interaction with mucin glycoprotein
    • 1:CAS:528:DyaK2MXntlCgtb4%3D 10.1016/0016-5085(95)90340-2 7615201
    • H Kindon C Pothoulakis L Thim K Lynch-Devaney DK Podolsky 1995 Trefoil peptide protection of intestinal epithelial barrier function: cooperative interaction with mucin glycoprotein Gastroenterology 109 516 523 1:CAS:528:DyaK2MXntlCgtb4%3D 10.1016/0016-5085(95)90340-2 7615201
    • (1995) Gastroenterology , vol.109 , pp. 516-523
    • Kindon, H.1    Pothoulakis, C.2    Thim, L.3    Lynch-Devaney, K.4    Podolsky, D.K.5
  • 49
    • 0025216985 scopus 로고
    • The jejunal secretion of histamine is increased in active Crohn's disease
    • 1:STN:280:DyaK3c7osFSjtg%3D%3D 1690156
    • L Knutson O Ahrenstedt B Odlind R Hallgren 1990 The jejunal secretion of histamine is increased in active Crohn's disease Gastroenterology 98 849 854 1:STN:280:DyaK3c7osFSjtg%3D%3D 1690156
    • (1990) Gastroenterology , vol.98 , pp. 849-854
    • Knutson, L.1    Ahrenstedt, O.2    Odlind, B.3    Hallgren, R.4
  • 50
    • 38049177193 scopus 로고    scopus 로고
    • The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction
    • 1:CAS:528:DC%2BD1cXitVWiurw%3D 17970764
    • TA Kufer E Kremmer AC Adam DJ Philpott PJ Sansonetti 2008 The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction Cell Microbiol 10 477 486 1:CAS:528: DC%2BD1cXitVWiurw%3D 17970764
    • (2008) Cell Microbiol , vol.10 , pp. 477-486
    • Kufer, T.A.1    Kremmer, E.2    Adam, A.C.3    Philpott, D.J.4    Sansonetti, P.J.5
  • 52
    • 12344285378 scopus 로고    scopus 로고
    • Salmonella typhimurium transcytoses flagellin via an SPI2-mediated vesicular transport pathway
    • DOI 10.1242/jcs.01500
    • S Lyons L Wang JE Casanova SV Sitaraman D Merlin AT Gewirtz 2004 Salmonella typhimurium transcytoses flagellin via an SPI2-mediated vesicular transport pathway J Cell Sci 117 5771 5780 1:CAS:528:DC%2BD2MXlvFSgsg%3D%3D 10.1242/jcs.01500 15507487 (Pubitemid 40123944)
    • (2004) Journal of Cell Science , vol.117 , Issue.24 , pp. 5771-5780
    • Lyons, S.1    Wang, L.2    Casanova, J.E.3    Sitaraman, S.V.4    Merlin, D.5    Gewirtz, A.T.6
  • 53
    • 2542475306 scopus 로고    scopus 로고
    • Interaction of pathogenic bacteria with rabbit appendix M cells: Bacterial motility is a key feature in vivo
    • DOI 10.1016/j.micinf.2004.02.009, PII S1286457904000875
    • M Marchetti JC Sirard P Sansonetti E Pringault S Kerneis 2004 Interaction of pathogenic bacteria with rabbit appendix M cells: bacterial motility is a key feature in vivo Microbes Infect 6 521 528 1:CAS:528:DC%2BD2cXktF2qsrY%3D 10.1016/j.micinf.2004.02.009 15158184 (Pubitemid 38680592)
    • (2004) Microbes and Infection , vol.6 , Issue.6 , pp. 521-528
    • Marchetti, M.1    Sirard, J.C.2    Sansonetti, P.3    Pringault, E.4    Kerneis, S.5
  • 54
    • 0030845121 scopus 로고    scopus 로고
    • Invasin-dependent and invasin-independent pathways for translocation of Yersinia pseudotuberculosis across the Peyer's patch intestinal epithelium
    • 1:CAS:528:DyaK2sXkvVars74%3D 9234806
    • A Marra RR Isberg 1997 Invasin-dependent and invasin-independent pathways for translocation of Yersinia pseudotuberculosis across the Peyer's patch intestinal epithelium Infect Immun 65 3412 3421 1:CAS:528:DyaK2sXkvVars74%3D 9234806
    • (1997) Infect Immun , vol.65 , pp. 3412-3421
    • Marra, A.1    Isberg, R.R.2
  • 55
    • 70350437264 scopus 로고    scopus 로고
    • Alpha-defensins in enteric innate immunity: Functional Paneth cell alpha-defensins in mouse colonic lumen
    • 1:CAS:528:DC%2BD1MXht1Sqsb7K 10.1074/jbc.M109.050773 19687006
    • JR Mastroianni AJ Ouellette 2009 Alpha-defensins in enteric innate immunity: functional Paneth cell alpha-defensins in mouse colonic lumen J Biol Chem 284 27848 27856 1:CAS:528:DC%2BD1MXht1Sqsb7K 10.1074/jbc.M109.050773 19687006
    • (2009) J Biol Chem , vol.284 , pp. 27848-27856
    • Mastroianni, J.R.1    Ouellette, A.J.2
  • 56
    • 0035011324 scopus 로고    scopus 로고
    • Colonic epithelial hPepT1 expression occurs in inflammatory bowel disease: Transport of bacterial peptides influences expression of MHC class 1 molecules
    • 1:CAS:528:DC%2BD3MXkslGkurc%3D 10.1053/gast.2001.24845 11375948
    • D Merlin M Si-Tahar SV Sitaraman K Eastburn I Williams X Liu MA Hediger JL Madara 2001 Colonic epithelial hPepT1 expression occurs in inflammatory bowel disease: transport of bacterial peptides influences expression of MHC class 1 molecules Gastroenterology 120 1666 1679 1:CAS:528:DC%2BD3MXkslGkurc%3D 10.1053/gast.2001.24845 11375948
    • (2001) Gastroenterology , vol.120 , pp. 1666-1679
    • Merlin, D.1    Si-Tahar, M.2    Sitaraman, S.V.3    Eastburn, K.4    Williams, I.5    Liu, X.6    Hediger, M.A.7    Madara, J.L.8
  • 57
    • 0028202474 scopus 로고
    • Transepithelial transport of immunoglobulins
    • 1:CAS:528:DyaK2cXivFKjurs%3D 10.1146/annurev.iy.12.040194.000431 8011293
    • KE Mostov 1994 Transepithelial transport of immunoglobulins Annu Rev Immunol 12 63 84 1:CAS:528:DyaK2cXivFKjurs%3D 10.1146/annurev.iy.12.040194. 000431 8011293
    • (1994) Annu Rev Immunol , vol.12 , pp. 63-84
    • Mostov, K.E.1
  • 59
    • 34548130847 scopus 로고    scopus 로고
    • Reduced mucosal antimicrobial activity in Crohn's disease of the colon
    • DOI 10.1136/gut.2006.118646
    • S Nuding K Fellermann J Wehkamp EF Stange 2007 Reduced mucosal antimicrobial activity in Crohn's disease of the colon Gut 56 1240 1247 10.1136/gut.2006.118646 17456510 (Pubitemid 47300425)
    • (2007) Gut , vol.56 , Issue.9 , pp. 1240-1247
    • Nuding, S.1    Fellermann, K.2    Wehkamp, J.3    Stange, E.F.4
  • 60
    • 0028786658 scopus 로고
    • Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia
    • 1:CAS:528:DyaK2MXptlSjtLk%3D 10.1073/pnas.92.23.10629 7479854
    • A Nusrat M Giry JR Turner SP Colgan CA Parkos D Carnes E Lemichez P Boquet JL Madara 1995 Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia Proc Natl Acad Sci USA 92 10629 10633 1:CAS:528:DyaK2MXptlSjtLk%3D 10.1073/pnas.92.23.10629 7479854
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 10629-10633
    • Nusrat, A.1    Giry, M.2    Turner, J.R.3    Colgan, S.P.4    Parkos, C.A.5    Carnes, D.6    Lemichez, E.7    Boquet, P.8    Madara, J.L.9
  • 61
    • 0035112067 scopus 로고    scopus 로고
    • Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins
    • DOI 10.1128/IAI.69.3.1329-1336.2001
    • A Nusrat C von Eichel-Streiber JR Turner P Verkade JL Madara CA Parkos 2001 Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins Infect Immun 69 1329 1336 1:CAS:528:DC%2BD3MXitFGrtr4%3D 10.1128/IAI.69.3.1329-1336. 2001 11179295 (Pubitemid 32187577)
    • (2001) Infection and Immunity , vol.69 , Issue.3 , pp. 1329-1336
    • Nusrat, A.1    Von Eichel-Streiber, C.2    Turner, J.R.3    Verkade, P.4    Madara, J.L.5    Parkos, C.A.6
  • 63
    • 0028231764 scopus 로고
    • Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers
    • 1:CAS:528:DyaK2cXkslGkt7w%3D 10.1073/pnas.91.9.3814 8170993
    • E Oswald M Sugai A Labigne HC Wu C Fiorentini P Boquet AD O'Brien 1994 Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers Proc Natl Acad Sci USA 91 3814 3818 1:CAS:528:DyaK2cXkslGkt7w%3D 10.1073/pnas.91.9.3814 8170993
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3814-3818
    • Oswald, E.1    Sugai, M.2    Labigne, A.3    Wu, H.C.4    Fiorentini, C.5    Boquet, P.6    O'Brien, A.D.7
  • 64
    • 0029819784 scopus 로고    scopus 로고
    • Paneth cell defensins: Endogenous peptide components of intestinal host defense
    • 1:CAS:528:DyaK28XlsleisL0%3D 8836041
    • AJ Ouellette ME Selsted 1996 Paneth cell defensins: endogenous peptide components of intestinal host defense FASEB J 10 1280 1289 1:CAS:528: DyaK28XlsleisL0%3D 8836041
    • (1996) FASEB J , vol.10 , pp. 1280-1289
    • Ouellette, A.J.1    Selsted, M.E.2
  • 65
    • 0142123222 scopus 로고    scopus 로고
    • Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists
    • DOI 10.1128/MCB.23.21.7531-7539.2003
    • AL Pauleau PJ Murray 2003 Role of nod2 in the response of macrophages to Toll-like receptor agonists Mol Cell Biol 23 7531 7539 1:CAS:528: DC%2BD3sXosFOgsbs%3D 10.1128/MCB.23.21.7531-7539.2003 14560001 (Pubitemid 37271454)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.21 , pp. 7531-7539
    • Pauleau, A.-L.1    Murray, P.J.2
  • 66
    • 0028203807 scopus 로고
    • Polymorphonuclear leukocyte transmigration promotes invasion of colonic epithelial monolayer by Shigella flexneri
    • 1:STN:280:DyaK2c7lslSrsw%3D%3D 10.1172/JCI117015 7906696
    • JJ Perdomo P Gounon PJ Sansonetti 1994 Polymorphonuclear leukocyte transmigration promotes invasion of colonic epithelial monolayer by Shigella flexneri J Clin Invest 93 633 643 1:STN:280:DyaK2c7lslSrsw%3D%3D 10.1172/JCI117015 7906696
    • (1994) J Clin Invest , vol.93 , pp. 633-643
    • Perdomo, J.J.1    Gounon, P.2    Sansonetti, P.J.3
  • 70
    • 0029082970 scopus 로고
    • Mucosal histamine content and histamine secretion in Crohn's disease, ulcerative colitis and allergic enteropathy
    • 1:CAS:528:DyaK2MXptl2hs7k%3D 10.1159/000237129 7549499
    • M Raithel M Matek HW Baenkler W Jorde EG Hahn 1995 Mucosal histamine content and histamine secretion in Crohn's disease, ulcerative colitis and allergic enteropathy Int Arch Allergy Immunol 108 127 133 1:CAS:528: DyaK2MXptl2hs7k%3D 10.1159/000237129 7549499
    • (1995) Int Arch Allergy Immunol , vol.108 , pp. 127-133
    • Raithel, M.1    Matek, M.2    Baenkler, H.W.3    Jorde, W.4    Hahn, E.G.5
  • 71
    • 0036300466 scopus 로고    scopus 로고
    • Shigella flexneri regulates tight junction-associated proteins in human intestinal epithelial cells
    • DOI 10.1046/j.1462-5822.2002.00197.x
    • T Sakaguchi H Kohler X Gu BA McCormick HC Reinecker 2002 Shigella flexneri regulates tight junction-associated proteins in human intestinal epithelial cells Cell Microbiol 4 367 381 1:CAS:528:DC%2BD38Xlt1Skt7w%3D 10.1046/j.1462-5822.2002.00197.x 12067320 (Pubitemid 34727540)
    • (2002) Cellular Microbiology , vol.4 , Issue.6 , pp. 367-381
    • Sakaguchi, T.1    Kohler, H.2    Gu, X.3    McCormick, B.A.4    Reinecker, H.-C.5
  • 72
    • 0037417311 scopus 로고    scopus 로고
    • Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin
    • DOI 10.1038/nature01520
    • NH Salzman D Ghosh KM Huttner Y Paterson CL Bevins 2003 Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin Nature 422 522 526 1:CAS:528:DC%2BD3sXisFCisrs%3D 10.1038/nature01520 12660734 (Pubitemid 36433647)
    • (2003) Nature , vol.422 , Issue.6931 , pp. 522-526
    • Salzman, N.H.1    Ghosh, D.2    Huttner, K.M.3    Paterson, Y.4    Bevins, C.L.5
  • 73
    • 34249313567 scopus 로고    scopus 로고
    • Paneth cells, defensins, and the commensal microbiota: A hypothesis on intimate interplay at the intestinal mucosa
    • DOI 10.1016/j.smim.2007.04.002, PII S1044532307000322, The armed truce between the intestinal microflora and host mucosal immunity
    • NH Salzman MA Underwood CL Bevins 2007 Paneth cells, defensins, and the commensal microbiota: a hypothesis on intimate interplay at the intestinal mucosa Semin Immunol 19 70 83 1:CAS:528:DC%2BD2sXmtVOksrs%3D 10.1016/j.smim.2007.04.002 17485224 (Pubitemid 46824070)
    • (2007) Seminars in Immunology , vol.19 , Issue.2 , pp. 70-83
    • Salzman, N.H.1    Underwood, M.A.2    Bevins, C.L.3
  • 75
    • 0029945905 scopus 로고    scopus 로고
    • Infection of rabbit Peyer's patches by Shigella flexneri: Effect of adhesive or invasive bacterial phenotypes on follicle-associated epithelium
    • 1:CAS:528:DyaK28XjvFajsro%3D 8698505
    • PJ Sansonetti J Arondel JR Cantey MC Prevost M Huerre 1996 Infection of rabbit Peyer's patches by Shigella flexneri: effect of adhesive or invasive bacterial phenotypes on follicle-associated epithelium Infect Immun 64 2752 2764 1:CAS:528:DyaK28XjvFajsro%3D 8698505
    • (1996) Infect Immun , vol.64 , pp. 2752-2764
    • Sansonetti, P.J.1    Arondel, J.2    Cantey, J.R.3    Prevost, M.C.4    Huerre, M.5
  • 76
    • 0033213989 scopus 로고    scopus 로고
    • Epithelial antimicrobial peptides: Innate local host response elements
    • DOI 10.1007/s000180050004
    • JM Schröder 1999 Epithelial antimicrobial peptides: innate local host response elements Cell Mol Life Sci 56 32 46 10.1007/s000180050004 11213259 (Pubitemid 29471923)
    • (1999) Cellular and Molecular Life Sciences , vol.56 , Issue.1-2 , pp. 32-46
    • Schroder, J.-M.1
  • 77
    • 78149285697 scopus 로고    scopus 로고
    • Loss of the intestinal mucus layer in the normal rat causes gut injury, but not toxic mesenteric lymph nor lung injury
    • 10.1097/SHK.0b013e3181dc3ff5 20220565
    • SM Sharpe X Qin Q Lu E Feketeova DC Palange W Dong SU Sheth MA Lee D Reino DZ Xu EA Deitch 2010 Loss of the intestinal mucus layer in the normal rat causes gut injury, but not toxic mesenteric lymph nor lung injury Shock 34 475 481 10.1097/SHK.0b013e3181dc3ff5 20220565
    • (2010) Shock , vol.34 , pp. 475-481
    • Sharpe, S.M.1    Qin, X.2    Lu, Q.3    Feketeova, E.4    Palange, D.C.5    Dong, W.6    Sheth, S.U.7    Lee, M.A.8    Reino, D.9    Xu, D.Z.10    Deitch, E.A.11
  • 78
    • 0033853899 scopus 로고    scopus 로고
    • Enteropathogenic Escherichia coli dephosphorylates and dissociates occludin from intestinal epithelial tight junctions
    • DOI 10.1046/j.1462-5822.2000.00055.x
    • I Simonovic J Rosenberg A Koutsouris G Hecht 2000 Enteropathogenic Escherichia coli dephosphorylates and dissociates occludin from intestinal epithelial tight junctions Cell Microbiol 2 305 315 1:CAS:528: DC%2BD3cXmtFOrsr8%3D 10.1046/j.1462-5822.2000.00055.x 11207587 (Pubitemid 30612940)
    • (2000) Cellular Microbiology , vol.2 , Issue.4 , pp. 305-315
    • Simonovic, I.1    Rosenberg, J.2    Koutsouris, A.3    Hecht, G.4
  • 79
    • 0033523773 scopus 로고    scopus 로고
    • Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier
    • DOI 10.1083/jcb.147.1.195
    • N Sonoda M Furuse H Sasaki S Yonemura J Katahira Y Horiguchi S Tsukita 1999 Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: evidence for direct involvement of claudins in tight junction barrier J Cell Biol 147 195 204 10.1083/jcb.147.1.195 10508866 (Pubitemid 30211807)
    • (1999) Journal of Cell Biology , vol.147 , Issue.1 , pp. 195-204
    • Sonoda, N.1    Furuse, M.2    Sasaki, H.3    Yonemura, S.4    Katahira, J.5    Horiguchi, Y.6    Tsukita, S.7
  • 80
    • 0012929728 scopus 로고    scopus 로고
    • Toll-like receptors
    • DOI 10.1146/annurev.immunol.21.120601.141126
    • K Takeda T Kaisho S Akira 2003 Toll-like receptors Annu Rev Immunol 21 335 376 1:CAS:528:DC%2BD3sXjtF2isrg%3D 10.1146/annurev.immunol.21.120601.141126 12524386 (Pubitemid 37174535)
    • (2003) Annual Review of Immunology , vol.21 , pp. 335-376
    • Takeda, K.1    Kaisho, T.2    Akira, S.3
  • 81
    • 0033569410 scopus 로고    scopus 로고
    • A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins
    • 1:CAS:528:DyaK1MXmvVOhtLg%3D 10.1126/science.286.5439.498 10521339
    • YQ Tang J Yuan G Osapay K Osapay D Tran CJ Miller AJ Ouellette ME Selsted 1999 A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins Science 286 498 502 1:CAS:528:DyaK1MXmvVOhtLg%3D 10.1126/science.286.5439.498 10521339
    • (1999) Science , vol.286 , pp. 498-502
    • Tang, Y.Q.1    Yuan, J.2    Osapay, G.3    Osapay, K.4    Tran, D.5    Miller, C.J.6    Ouellette, A.J.7    Selsted, M.E.8
  • 82
    • 0038305104 scopus 로고    scopus 로고
    • Antimicrobial peptides in the first line defence of human colon mucosa
    • DOI 10.1016/S0196-9781(03)00114-1
    • M Tollin P Bergman T Svenberg H Jornvall GH Gudmundsson B Agerberth 2003 Antimicrobial peptides in the first line defence of human colon mucosa Peptides 24 523 530 1:CAS:528:DC%2BD3sXltF2msrs%3D 10.1016/S0196-9781(03)00114-1 12860195 (Pubitemid 36829340)
    • (2003) Peptides , vol.24 , Issue.4 , pp. 523-530
    • Tollin, M.1    Bergman, P.2    Svenberg, T.3    Jornvall, H.4    Gudmundsson, G.H.5    Agerberth, B.6
  • 83
    • 58549111588 scopus 로고    scopus 로고
    • Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
    • 1:CAS:528:DC%2BD1MXksFSntQ%3D%3D 10.1073/pnas.0808723105 19075245
    • S Vaishnava CL Behrendt AS Ismail L Eckmann LV Hooper 2008 Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface Proc Natl Acad Sci USA 105 20858 20863 1:CAS:528:DC%2BD1MXksFSntQ%3D%3D 10.1073/pnas.0808723105 19075245
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 20858-20863
    • Vaishnava, S.1    Behrendt, C.L.2    Ismail, A.S.3    Eckmann, L.4    Hooper, L.V.5
  • 84
    • 7644234401 scopus 로고    scopus 로고
    • hPepT1 transports muramyl dipeptide, activating NF-κB and stimulating IL-8 secretion in human colonic Caco2/bbe cells
    • DOI 10.1053/j.gastro.2004.07.024, PII S0016508504013320
    • SR Vavricka MW Musch JE Chang Y Nakagawa K Phanvijhitsiri TS Waypa D Merlin O Schneewind EB Chang 2004 hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells Gastroenterology 127 1401 1409 1:CAS:528:DC%2BD2cXhtVKisrzE 10.1053/j.gastro.2004.07.024 15521010 (Pubitemid 39457767)
    • (2004) Gastroenterology , vol.127 , Issue.5 , pp. 1401-1409
    • Vavricka, S.R.1    Musch, M.W.2    Chang, J.E.3    Nakagawa, Y.4    Phanvijhitsiri, K.5    Waypa, T.S.6    Merlin, D.7    Schneewind, O.8    Chang, E.B.9
  • 86
    • 0033214433 scopus 로고    scopus 로고
    • Regulation of intestinal α-defensin activation by the metalloproteinase matrilysin in innate host defense
    • DOI 10.1126/science.286.5437.113
    • CL Wilson AJ Ouellette DP Satchell T Ayabe YS Lopez-Boado JL Stratman SJ Hultgren LM Matrisian WC Parks 1999 Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense Science 286 113 117 1:CAS:528:DyaK1MXmsFehurc%3D 10.1126/science.286.5437.113 10506557 (Pubitemid 29484488)
    • (1999) Science , vol.286 , Issue.5437 , pp. 113-117
    • Wilson, C.L.1    Ouellette, A.J.2    Satchell, D.P.3    Ayabe, T.4    Lopez-Boado, Y.S.5    Stratman, J.L.6    Hultgren, S.J.7    Matrisian, L.M.8    Parks, W.C.9
  • 87
    • 0033521140 scopus 로고    scopus 로고
    • Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3
    • 1:CAS:528:DyaK1MXnvFyrur4%3D 10.1074/jbc.274.49.35179 10575001
    • ES Wittchen J Haskins BR Stevenson 1999 Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3 J Biol Chem 274 35179 35185 1:CAS:528: DyaK1MXnvFyrur4%3D 10.1074/jbc.274.49.35179 10575001
    • (1999) J Biol Chem , vol.274 , pp. 35179-35185
    • Wittchen, E.S.1    Haskins, J.2    Stevenson, B.R.3
  • 88
    • 0030569343 scopus 로고    scopus 로고
    • Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells
    • DOI 10.1016/0014-5793(96)01123-4, PII S0014579396011234
    • C Zhao I Wang RI Lehrer 1996 Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells FEBS Lett 396 319 322 1:CAS:528:DyaK28Xms1ehsrs%3D 10.1016/0014-5793(96)01123-4 8915011 (Pubitemid 26377848)
    • (1996) FEBS Letters , vol.396 , Issue.2-3 , pp. 319-322
    • Zhao, C.1    Wang, I.2    Lehrer, R.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.