메뉴 건너뛰기




Volumn 88, Issue 3, 1998, Pages 221-225

β-defensins: Endogenous antibiotics of the innate host defense response

Author keywords

[No Author keywords available]

Indexed keywords

DEFENSIN;

EID: 0032168228     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1006/clin.1998.4587     Document Type: Review
Times cited : (140)

References (50)
  • 2
    • 0028933794 scopus 로고
    • Peptide antibiotics and their role in innate immunity
    • Boman H. G. Peptide antibiotics and their role in innate immunity. Annu. Rev. Immunol. 13:1995;61-92.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 61-92
    • Boman, H.G.1
  • 3
    • 0030449497 scopus 로고    scopus 로고
    • Endogenous vertebrate antibiotics: Defensins, protegrins, and other cysteine-rich antimicrobial peptides
    • Lehrer R. I., Ganz T. Endogenous vertebrate antibiotics: Defensins, protegrins, and other cysteine-rich antimicrobial peptides. Ann. N.Y. Acad. Sci. 797:1996;228-239.
    • (1996) Ann. N.Y. Acad. Sci. , vol.797 , pp. 228-239
    • Lehrer, R.I.1    Ganz, T.2
  • 5
    • 0029051685 scopus 로고
    • Defensins and other endogenous peptide antibiotics of vertebrates
    • Martin E., Ganz T., Lehrer R. I. Defensins and other endogenous peptide antibiotics of vertebrates. J. Leukocyte Biol. 58:1995;128-136.
    • (1995) J. Leukocyte Biol. , vol.58 , pp. 128-136
    • Martin, E.1    Ganz, T.2    Lehrer, R.I.3
  • 6
    • 0025811874 scopus 로고
    • Tracheal antimicrobial peptide, a novel cysteine-rich peptide from mammalian tracheal mucosa: Peptide isolation and cloning of a cDNA
    • Diamond G., Zasloff M., Eck H., Brasseur M., Maloy W. L., Bevins C. L. Tracheal antimicrobial peptide, a novel cysteine-rich peptide from mammalian tracheal mucosa: Peptide isolation and cloning of a cDNA. Proc. Natl. Acad. Sci. USA. 88:1991;3952-3956.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3952-3956
    • Diamond, G.1    Zasloff, M.2    Eck, H.3    Brasseur, M.4    Maloy, W.L.5    Bevins, C.L.6
  • 7
    • 0021032178 scopus 로고
    • Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of rabbit lung macrophages
    • Selsted M. E., Brown D. M., DeLange R. J., Lehrer R. I. Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of rabbit lung macrophages. J. Biol. Chem. 258:1983;14485-14489.
    • (1983) J. Biol. Chem. , vol.258 , pp. 14485-14489
    • Selsted, M.E.1    Brown, D.M.2    DeLange, R.J.3    Lehrer, R.I.4
  • 9
    • 0026535104 scopus 로고
    • Posttranslational processing of defensins in immature human myeloid cells
    • Valore E. V., Ganz T. Posttranslational processing of defensins in immature human myeloid cells. Blood. 79:1992;1538-1544.
    • (1992) Blood , vol.79 , pp. 1538-1544
    • Valore, E.V.1    Ganz, T.2
  • 10
    • 0021142387 scopus 로고
    • Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes
    • Selsted M. E., Szlarek D., Lehrer R. I. Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes. Infect. Immun. 45:1984;150-154.
    • (1984) Infect. Immun. , vol.45 , pp. 150-154
    • Selsted, M.E.1    Szlarek, D.2    Lehrer, R.I.3
  • 12
    • 0021792199 scopus 로고
    • Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes
    • Lehrer R. I., Daher K., Ganz T., Selsted M. E. Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes. J. Virol. 54:1985;467-472.
    • (1985) J. Virol. , vol.54 , pp. 467-472
    • Lehrer, R.I.1    Daher, K.2    Ganz, T.3    Selsted, M.E.4
  • 13
    • 0023882266 scopus 로고
    • Oxygen-independent bactericidal systems: Mechanisms and disorders
    • Lehrer R. I., Ganz T., Selsted M. E. Oxygen-independent bactericidal systems: Mechanisms and disorders. Hematol. Oncol. Clin. North Am. 2:1988;159-169.
    • (1988) Hematol. Oncol. Clin. North Am. , vol.2 , pp. 159-169
    • Lehrer, R.I.1    Ganz, T.2    Selsted, M.E.3
  • 15
    • 0026457997 scopus 로고
    • Paneth cells of the human small intestine express an antimicrobial peptide gene
    • Jones D. E., Bevins C. L. Paneth cells of the human small intestine express an antimicrobial peptide gene. J. Biol. Chem. 267:1992;23216-23225.
    • (1992) J. Biol. Chem. , vol.267 , pp. 23216-23225
    • Jones, D.E.1    Bevins, C.L.2
  • 16
    • 0029819784 scopus 로고    scopus 로고
    • Paneth cell defensins: Endogenous peptide components of intestinal host defense
    • Ouellette A. J., Selsted M. E. Paneth cell defensins: Endogenous peptide components of intestinal host defense. FASEB J. 10:1996;1280-1289.
    • (1996) FASEB J. , vol.10 , pp. 1280-1289
    • Ouellette, A.J.1    Selsted, M.E.2
  • 17
    • 0031898688 scopus 로고    scopus 로고
    • Gene expression, immunolocalization and secretion of human defensin-5 in human female genital tract
    • Quayle A. J., Martin Porter E., Nussbaum A. A., Wang Y.-M., Brabec C., Mok S. C. Gene expression, immunolocalization and secretion of human defensin-5 in human female genital tract. Am. J. Pathol. 152:1998;1247-1258.
    • (1998) Am. J. Pathol. , vol.152 , pp. 1247-1258
    • Quayle, A.J.1    Martin Porter, E.2    Nussbaum, A.A.3    Wang, Y.-M.4    Brabec, C.5    Mok, S.C.6
  • 18
    • 0027298895 scopus 로고
    • Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene
    • Diamond G., Jones D. E., Bevins C. L. Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene. Proc. Nat. Acad. Sci. USA. 90:1993;4596-4600.
    • (1993) Proc. Nat. Acad. Sci. USA , vol.90 , pp. 4596-4600
    • Diamond, G.1    Jones, D.E.2    Bevins, C.L.3
  • 19
    • 0027514011 scopus 로고
    • Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils
    • Selsted M. E., Tang Y.-Q., Morris W. L., McGuire P. A., Novotny M. J., Smith W., Henschen A. H., Cullor J. S. Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils. J. Biol. Chem. 268:1993;6641-6648.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6641-6648
    • Selsted, M.E.1    Tang, Y.-Q.2    Morris, W.L.3    McGuire, P.A.4    Novotny, M.J.5    Smith, W.6    Henschen, A.H.7    Cullor, J.S.8
  • 20
    • 0027414945 scopus 로고
    • Characterization of the disulfide motif in BNBD-12, an antimicrobial beta-defensin peptide from bovine neutrophils
    • Tang Y.-Q., Selsted M. E. Characterization of the disulfide motif in BNBD-12, an antimicrobial beta-defensin peptide from bovine neutrophils. J. Biol. Chem. 268:1993;6649-6653.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6649-6653
    • Tang, Y.-Q.1    Selsted, M.E.2
  • 21
    • 0028825285 scopus 로고
    • Solution structure of bovine neutrophil β-defensin-12: The peptide fold of the β-defensins is identical to that of classical defensins
    • Zimmermann G. R., Legault P., Selsted M. E., Pardi A. Solution structure of bovine neutrophil β-defensin-12: The peptide fold of the β-defensins is identical to that of classical defensins. Biochemistry. 34:1995;13663-13671.
    • (1995) Biochemistry , vol.34 , pp. 13663-13671
    • Zimmermann, G.R.1    Legault, P.2    Selsted, M.E.3    Pardi, A.4
  • 22
    • 0028902757 scopus 로고
    • Epithelial antibiotics induced at sites of inflammation
    • Schonwetter B. S., Stolzenberg E. D., Zasloff M. A. Epithelial antibiotics induced at sites of inflammation. Science. 267:1995;1645-1648.
    • (1995) Science , vol.267 , pp. 1645-1648
    • Schonwetter, B.S.1    Stolzenberg, E.D.2    Zasloff, M.A.3
  • 23
    • 0029877550 scopus 로고    scopus 로고
    • Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to the inflammatory mediators lipopolysaccharide and tumor necrosis factor alpha
    • Russell J. P., Diamond G., Tarver A. P., Scanlin T. F., Bevins C. L. Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to the inflammatory mediators lipopolysaccharide and tumor necrosis factor alpha. Infect. Immun. 64:1996;1565-1568.
    • (1996) Infect. Immun. , vol.64 , pp. 1565-1568
    • Russell, J.P.1    Diamond, G.2    Tarver, A.P.3    Scanlin, T.F.4    Bevins, C.L.5
  • 25
    • 0031882530 scopus 로고    scopus 로고
    • Expression of beta-defensin genes in bovine alveolar macrophages
    • Ryan L. K., Rhodes J., Bhat M., Diamond G. Expression of beta-defensin genes in bovine alveolar macrophages. Infect. Immun. 66:1998;878-881.
    • (1998) Infect. Immun. , vol.66 , pp. 878-881
    • Ryan, L.K.1    Rhodes, J.2    Bhat, M.3    Diamond, G.4
  • 32
    • 0030747618 scopus 로고    scopus 로고
    • The mouse genome encodes a single homolog of the antimicrobial peptide human beta-defensin 1
    • Huttner K. M., Kozak C. A., Bevins C. L. The mouse genome encodes a single homolog of the antimicrobial peptide human beta-defensin 1. FEBS Lett. 413:1997;45-49.
    • (1997) FEBS Lett. , vol.413 , pp. 45-49
    • Huttner, K.M.1    Kozak, C.A.2    Bevins, C.L.3
  • 33
    • 0031913244 scopus 로고    scopus 로고
    • Mouse β-defensin 1 is a salt-sensitive antimicrobial peptide present in epithelia of the lung and urogenital tract
    • Bals R., Goldman M. J., Wilson J. M. Mouse β-defensin 1 is a salt-sensitive antimicrobial peptide present in epithelia of the lung and urogenital tract. Infect. Immun. 66:1998;1225-1232.
    • (1998) Infect. Immun. , vol.66 , pp. 1225-1232
    • Bals, R.1    Goldman, M.J.2    Wilson, J.M.3
  • 34
    • 0032489350 scopus 로고    scopus 로고
    • Molecular cloning and tissue expression of procine β-defensin-1
    • Zhang G., Wu H., Shi J., Ganz T., Ross C. R., Blecha F. Molecular cloning and tissue expression of procine β-defensin-1. FEBS Lett. 424:1998;37-40.
    • (1998) FEBS Lett. , vol.424 , pp. 37-40
    • Zhang, G.1    Wu, H.2    Shi, J.3    Ganz, T.4    Ross, C.R.5    Blecha, F.6
  • 35
    • 0031937280 scopus 로고    scopus 로고
    • Antimicrobial peptide expression is developmentally-regulated in the ovine gastrointestinal tract
    • Huttner K. M., Brezinski-Caliguri D. J., Mahoney M. M., Diamond G. Antimicrobial peptide expression is developmentally-regulated in the ovine gastrointestinal tract. J. Nutr. 128:1998;297S-299S.
    • (1998) J. Nutr. , vol.128
    • Huttner, K.M.1    Brezinski-Caliguri, D.J.2    Mahoney, M.M.3    Diamond, G.4
  • 36
    • 0031213832 scopus 로고    scopus 로고
    • The human β-defensin-1 and α-defensins are encoded by adjacent genes: Two peptide families with differing disulfide topology share a common ancestry
    • Liu L., Zhao C., Heng H. H. Q., Ganz T. The human β-defensin-1 and α-defensins are encoded by adjacent genes: Two peptide families with differing disulfide topology share a common ancestry. Genomics. 43:1997;316-320.
    • (1997) Genomics , vol.43 , pp. 316-320
    • Liu, L.1    Zhao, C.2    Heng, H.H.Q.3    Ganz, T.4
  • 38
    • 0030027096 scopus 로고    scopus 로고
    • Human enteric defensin genes: Chromosomal map position and a model for possible evolutionary relationships
    • Bevins C. L., Jones D. E., Dutra A., Schaffzin J., Muenke M. Human enteric defensin genes: Chromosomal map position and a model for possible evolutionary relationships. Genomics. 31:1996;95-106.
    • (1996) Genomics , vol.31 , pp. 95-106
    • Bevins, C.L.1    Jones, D.E.2    Dutra, A.3    Schaffzin, J.4    Muenke, M.5
  • 39
    • 0024711951 scopus 로고
    • Localization of the cryptdin locus on mouse chromosome 8
    • Ouellette A. J., Pravtcheva D., Ruddle F. H., James M. Localization of the cryptdin locus on mouse chromosome 8. Genomics. 5:1989;233-239.
    • (1989) Genomics , vol.5 , pp. 233-239
    • Ouellette, A.J.1    Pravtcheva, D.2    Ruddle, F.H.3    James, M.4
  • 40
    • 0029347185 scopus 로고
    • Somatic cell mapping of beta-defensin genes to cattle syntenic group U25 and fluoresence in situ localization to chromosome 27
    • Gallagher D. S. Jr., Ryan A. M., Diamond G., Bevins C. L., Womack J. E. Somatic cell mapping of beta-defensin genes to cattle syntenic group U25 and fluoresence in situ localization to chromosome 27. Mamm. Genome. 6:1995;554-556.
    • (1995) Mamm. Genome , vol.6 , pp. 554-556
    • Gallagher D.S., Jr.1    Ryan, A.M.2    Diamond, G.3    Bevins, C.L.4    Womack, J.E.5
  • 41
    • 0032484654 scopus 로고    scopus 로고
    • Localization and genomic organization of sheep antimicrobial peptide genes
    • Huttner K. M., Lambeth M. R., Burkin H. R., Burkin D. J., Broad T. E. Localization and genomic organization of sheep antimicrobial peptide genes. Gene. 206:1998;85-91.
    • (1998) Gene , vol.206 , pp. 85-91
    • Huttner, K.M.1    Lambeth, M.R.2    Burkin, H.R.3    Burkin, D.J.4    Broad, T.E.5
  • 42
    • 0030463889 scopus 로고    scopus 로고
    • High resolution FISH mapping of beta-defensin genes to river buffalo and sheep chromosomes suggests a chromosome discrepancy in cattle standard karyotypes
    • Iannuzzi L., Gallagher D. S., Di Meo G. P., Diamond G., Bevins C. L., Womack J. E. High resolution FISH mapping of beta-defensin genes to river buffalo and sheep chromosomes suggests a chromosome discrepancy in cattle standard karyotypes. Mamm. Genet. 75:1996;10-13.
    • (1996) Mamm. Genet. , vol.75 , pp. 10-13
    • Iannuzzi, L.1    Gallagher, D.S.2    Di Meo, G.P.3    Diamond, G.4    Bevins, C.L.5    Womack, J.E.6
  • 43
    • 0029900207 scopus 로고    scopus 로고
    • Inducible expression of an antibiotic peptide gene in lipopolysaccharide-challenged tracheal epithelial cells
    • Diamond G., Russell J. P., Bevins C. L. Inducible expression of an antibiotic peptide gene in lipopolysaccharide-challenged tracheal epithelial cells. Proc. Natl. Acad. Sci. USA. 93:1996;5156-5160.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5156-5160
    • Diamond, G.1    Russell, J.P.2    Bevins, C.L.3
  • 45
    • 0010240414 scopus 로고    scopus 로고
    • Inducible expression of a mammalian antibiotic peptide gene in tracheal cells
    • Bevins C. L., Russell J. P., Diamond G. Inducible expression of a mammalian antibiotic peptide gene in tracheal cells. Pediatr. Pulmon. Suppl. 1996.
    • (1996) Pediatr. Pulmon.
    • Bevins, C.L.1    Russell, J.P.2    Diamond, G.3
  • 46
    • 0030569343 scopus 로고    scopus 로고
    • Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells
    • Zhao C., Wang I., Lehrer R. I. Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells. FEBS Lett. 396:1996;319-322.
    • (1996) FEBS Lett. , vol.396 , pp. 319-322
    • Zhao, C.1    Wang, I.2    Lehrer, R.I.3
  • 48
    • 0030949875 scopus 로고    scopus 로고
    • Human β-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis
    • Goldman M. J., Anderson G. M., Stolzenberg E. D., Kari U. P., Zasloff M., Wilson J. M. Human β-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis. Cell. 88:1997;553-560.
    • (1997) Cell , vol.88 , pp. 553-560
    • Goldman, M.J.1    Anderson, G.M.2    Stolzenberg, E.D.3    Kari, U.P.4    Zasloff, M.5    Wilson, J.M.6
  • 49
    • 0030463948 scopus 로고    scopus 로고
    • Production of active bovine tracheal antimicrobial peptide in milk of transgenic mice
    • Yarus S., Rosen J. M., Cole A. M., Diamond G. Production of active bovine tracheal antimicrobial peptide in milk of transgenic mice. Proc. Natl. Acad. Sci. USA. 93:1996;14118-14121.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14118-14121
    • Yarus, S.1    Rosen, J.M.2    Cole, A.M.3    Diamond, G.4
  • 50
    • 0024511945 scopus 로고
    • Determination of the disulfide array in the human defensin HNP-2. A covalently cyclized peptide
    • Selsted M. E., Harwig S. S. Determination of the disulfide array in the human defensin HNP-2. A covalently cyclized peptide. J. Biol. Chem. 264:1989;4003-4007.
    • (1989) J. Biol. Chem. , vol.264 , pp. 4003-4007
    • Selsted, M.E.1    Harwig, S.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.