Probing bacterial pathogenesis with genetics, genomics, and chemical biology: Past, present, and future approaches

Critical Reviews in Biochemistry and Molecular Biology

Volumn 46, Issue 1, 2011, Pages 41-66

  Gomez, James E ^a   Clatworthy, Anne ^a,b   Hung, Deborah T ^a,b,c  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

IVET; libraries; mutagenesis; small molecules; STM; transposon; Virulence

Indexed keywords

RECOMBINASE;

BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIAL PATHOGENESIS; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM CULTURE; CHLAMYDOPHILA PNEUMONIAE; DNA MICROARRAY; ESCHERICHIA COLI; FLUORESCENCE; FLUORESCENCE ACTIVATED CELL SORTING; FUNCTIONAL GENOMICS; GENE EXPRESSION; GENE INTERACTION; GENE SEQUENCE; GENETIC CODE; GENETIC IDENTIFICATION; GENETIC VARIABILITY; HOST PATHOGEN INTERACTION; IN VITRO STUDY; IN VIVO STUDY; MYCOBACTERIUM MARINUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PSEUDOMONAS AERUGINOSA; REVIEW; SALMONELLA ENTERICA; SALMONELLA TYPHIMURIUM; SHIGELLA; VIBRIO CHOLERAE;

ANIMALS; BACTERIA; BACTERIAL INFECTIONS; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENOME, BACTERIAL; GENOMICS; HOST-PATHOGEN INTERACTIONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; SMALL MOLECULE LIBRARIES; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS);

EID: 78951489323     PISSN: 10409238     EISSN: 15497798     Source Type: Journal    
DOI: 10.3109/10409238.2010.538663     Document Type: Review

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