Host-induced epidemic spread of the cholera bacterium

Nature

Volumn 417, Issue 6889, 2002, Pages 642-645

  Merrell, D Scott ^a   Butler, Susan M ^a   Qadri, Firdausi ^b   Dolganov, Nadia A ^c   Alam, Ahsfaqul ^b   Cohen, Mitchell B ^d   Calderwood, Stephen B ^e,f   Schoolnik, Gary K ^c   Camilli, Andrew ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH   (Bangladesh)

^c STANFORD UNIVERSITY   (United States)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDITY; BEHAVIORAL RESEARCH; DIGESTIVE SYSTEM; DISEASES; EPIDEMIOLOGY; GENES; PHYSIOLOGICAL MODELS;

CHAEMOTAXIS;

BACTERIA;

DNA;

CHOLERA; DISEASE SPREAD; EPIDEMIC; HOST;

ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIAL INFECTION; BACTERIAL VIRULENCE; CHOLERA; DISEASE TRANSMISSION; DNA MICROARRAY; DNA SYNTHESIS; EPIDEMIC; FECES ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; VIBRIO CHOLERAE;

ANIMALS; ANIMALS, NEWBORN; BANGLADESH; CHEMOTAXIS; CHOLERA; FECES; FRESH WATER; GASTRIC ACID; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; HUMANS; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA, BACTERIAL; VIBRIO CHOLERAE;

BACTERIA (MICROORGANISMS); VIBRIO; VIBRIO CHOLERAE;

EID: 0037030671     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature00778     Document Type: Article

References (19)

1. Response of man to infection with Vibrio cholerae. 1. Clinical, serologic, and bacteriologic responses to a known inoculum
2. Gastrectomy, achlorhydria and cholera
3. Quantitative monitoring of gene expression patterns with a complementary DNA microarray
4. DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae
5. Enumeration of cholera vibrios in faecal samples
6. Significance analysis of microarrays applied to the ionizing radiation response
7. An evaluation of intestinal fluids in the pathogenesis of cholera
8. Synthesis of cholera toxin is positively regulated at the transcriptional level by toxR
9. Phase variation in tcpH modulates expression of the ToxR regulon in Vibrio cholerae
10. TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae
11. Regulatory cascade controls virulence in Vibrio cholerae
12. Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans
13. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae
14. The cadA gene of Vibrio cholerae is induced during infection and plays a role in acid tolerance
15. Whole genome DNA microarray expression analysis ofbiofilm development by Vibrio cholerae O 1 El Tor
16. Roles of motility and flagellar structure in pathogenicity, of Vibrio cholerae: Analysis of motility mutants in three animal models
17. Alterations in Vibrio cholerae motility phenotypes correlate with changes in virulence factor expression
18. Selection for in vivo regulators of bacterial virulence
19. Use of recombinase gene fusions to identify Vibrio cholerae genes induced during infection