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Volumn 463, Issue 7279, 2010, Pages

Essentiality of FASII pathway for Staphylococcus aureus

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; CERULETIDE; CG 400549; FATTY ACID; ISONIAZID; LINEZOLID; PLATENSIMYCIN; TRICLOSAN; TYPE II FATTY ACID; UNCLASSIFIED DRUG;

EID: 75149139456     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08667     Document Type: Note
Times cited : (130)

References (15)
  • 1
    • 61949263942 scopus 로고    scopus 로고
    • TypeII fatty acid synthesis isnot a suitable antibiotic target for Gram-positive pathogens
    • Brinster, S. etal. TypeII fatty acid synthesis isnot a suitable antibiotic target for Gram-positive pathogens. Nature 458, 83-86 (2009).
    • (2009) Nature , vol.458 , pp. 83-86
    • Brinster, S.1
  • 2
    • 28444471602 scopus 로고    scopus 로고
    • DltABCD-and MprF-mediated cell envelope modifications of Staphylococcus aureus confer resistance to platelet microbicidal proteins and contribute to virulence in a rabbit endocarditis model
    • Weidenmaier, C. et al. DltABCD-and MprF-mediated cell envelope modifications of Staphylococcus aureus confer resistance to platelet microbicidal proteins and contribute to virulence in a rabbit endocarditis model. Infect. Immun. 73, 8033-8038 (2005).
    • (2005) Infect. Immun. , vol.73 , pp. 8033-8038
    • Weidenmaier, C.1
  • 3
    • 0035821289 scopus 로고    scopus 로고
    • Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysine
    • Peschel, A. et al. Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysine. J. Exp. Med. 193, 1067-1076 (2001).
    • (2001) J. Exp. Med. , vol.193 , pp. 1067-1076
    • Peschel, A.1
  • 4
    • 4444291069 scopus 로고    scopus 로고
    • Interplay between mycobacteria and host signalling pathways
    • Koul, A., Herget, T., Klebl, B. & Ullrich, A. Interplay between mycobacteria and host signalling pathways. Nature Rev. Microbiol. 2, 189-202 (2004).
    • (2004) Nature Rev. Microbiol. , vol.2 , pp. 189-202
    • Koul, A.1    Herget, T.2    Klebl, B.3    Ullrich, A.4
  • 5
    • 0030964241 scopus 로고    scopus 로고
    • Exploitation of mammalian host cell functions by bacterial pathogens
    • Finlay, B. B. & Cossart, P. Exploitation of mammalian host cell functions by bacterial pathogens. Science 276, 718-725 (1997).
    • (1997) Science , vol.276 , pp. 718-725
    • Finlay, B.B.1    Cossart, P.2
  • 6
    • 0346605784 scopus 로고    scopus 로고
    • Validation of antibacterial mechanism of action using regulated antisense RNA expression in Staphylococcus aureus
    • Ji, Y. et al. Validation of antibacterial mechanism of action using regulated antisense RNA expression in Staphylococcus aureus. FEMS Microbiol. Lett. 231, 177-184 (2004).
    • (2004) FEMS Microbiol. Lett. , vol.231 , pp. 177-184
    • Ji, Y.1
  • 7
    • 0036863098 scopus 로고    scopus 로고
    • Mechanistic diversity and regulation of Type II fatty acid synthesis
    • Marrakchi, H., Zhang, Y. M. & Rock, C. O. Mechanistic diversity and regulation of Type II fatty acid synthesis. Biochem. Soc. Trans. 30, 1050-1055 (2002).
    • (2002) Biochem. Soc. Trans. , vol.30 , pp. 1050-1055
    • Marrakchi, H.1    Zhang, Y.M.2    Rock, C.O.3
  • 8
    • 36549008210 scopus 로고    scopus 로고
    • Isolation and characterization of unsaturated fatty acid auxotrophs of Streptococcus pneumoniae and Streptococcus mutans
    • Altabe, S., Lopez, P. & de Mendoza, D. Isolation and characterization of unsaturated fatty acid auxotrophs of Streptococcus pneumoniae and Streptococcus mutans. J. Bacteriol. 189, 8139-8144 (2007).
    • (2007) J. Bacteriol. , vol.189 , pp. 8139-8144
    • Altabe, S.1    Lopez, P.2    De Mendoza, D.3
  • 9
    • 39149115737 scopus 로고    scopus 로고
    • Membrane lipid homeostasis in bacteria
    • Zhang, Y. M. & Rock, C. O. Membrane lipid homeostasis in bacteria. Nature Rev. Microbiol. 6, 222-233 (2008)
    • (2008) Nature Rev. Microbiol. , vol.6 , pp. 222-233
    • Zhang, Y.M.1    Rock, C.O.2
  • 10
    • 0019763102 scopus 로고
    • Cerulenin
    • Omura, S. Cerulenin. Methods Enzymol. 72, 520-532 (1981).
    • (1981) Methods Enzymol. , vol.72 , pp. 520-532
    • Omura, S.1
  • 11
    • 0034804919 scopus 로고    scopus 로고
    • Lipid biosynthesis as a target for antibacterial agents
    • Heath, R. J., White, S. W. & Rock, C. O. Lipid biosynthesis as a target for antibacterial agents. Prog. Lipid Res. 40, 467-497 (2001).
    • (2001) Prog. Lipid Res. , vol.40 , pp. 467-497
    • Heath, R.J.1    White, S.W.2    Rock, C.O.3
  • 12
    • 33744994317 scopus 로고    scopus 로고
    • Platensimycin is a selective FabF inhibitor with potent antibiotic properties
    • Wang, J. et al. Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature 441, 358-361 (2006).
    • (2006) Nature , vol.441 , pp. 358-361
    • Wang, J.1
  • 13
    • 34447263022 scopus 로고    scopus 로고
    • In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea
    • Yum, J. H. et al. In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. Antimicrob. Agents Chemother. 51, 2591-2593 (2007).
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 2591-2593
    • Yum, J.H.1
  • 14
    • 0036783668 scopus 로고    scopus 로고
    • Discovery of a novel and potent class of FabI-directed antibacterial agents
    • Payne, D. J. et al. Discovery of a novel and potent class of FabI-directed antibacterial agents. Antimicrob. Agents Chemother. 46, 3118-3124 (2002).
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 3118-3124
    • Payne, D.J.1
  • 15
    • 33748469322 scopus 로고    scopus 로고
    • Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid
    • Vilcheze, C. et al. Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid. Nature Med. 12, 1027-1029 (2006).
    • (2006) Nature Med. , vol.12 , pp. 1027-1029
    • Vilcheze, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.