-
1
-
-
61949263942
-
TypeII fatty acid synthesis isnot a suitable antibiotic target for Gram-positive pathogens
-
Brinster, S. etal. TypeII fatty acid synthesis isnot a suitable antibiotic target for Gram-positive pathogens. Nature 458, 83-86 (2009).
-
(2009)
Nature
, vol.458
, pp. 83-86
-
-
Brinster, S.1
-
2
-
-
28444471602
-
DltABCD-and MprF-mediated cell envelope modifications of Staphylococcus aureus confer resistance to platelet microbicidal proteins and contribute to virulence in a rabbit endocarditis model
-
Weidenmaier, C. et al. DltABCD-and MprF-mediated cell envelope modifications of Staphylococcus aureus confer resistance to platelet microbicidal proteins and contribute to virulence in a rabbit endocarditis model. Infect. Immun. 73, 8033-8038 (2005).
-
(2005)
Infect. Immun.
, vol.73
, pp. 8033-8038
-
-
Weidenmaier, C.1
-
3
-
-
0035821289
-
Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysine
-
Peschel, A. et al. Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysine. J. Exp. Med. 193, 1067-1076 (2001).
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1067-1076
-
-
Peschel, A.1
-
4
-
-
4444291069
-
Interplay between mycobacteria and host signalling pathways
-
Koul, A., Herget, T., Klebl, B. & Ullrich, A. Interplay between mycobacteria and host signalling pathways. Nature Rev. Microbiol. 2, 189-202 (2004).
-
(2004)
Nature Rev. Microbiol.
, vol.2
, pp. 189-202
-
-
Koul, A.1
Herget, T.2
Klebl, B.3
Ullrich, A.4
-
5
-
-
0030964241
-
Exploitation of mammalian host cell functions by bacterial pathogens
-
Finlay, B. B. & Cossart, P. Exploitation of mammalian host cell functions by bacterial pathogens. Science 276, 718-725 (1997).
-
(1997)
Science
, vol.276
, pp. 718-725
-
-
Finlay, B.B.1
Cossart, P.2
-
6
-
-
0346605784
-
Validation of antibacterial mechanism of action using regulated antisense RNA expression in Staphylococcus aureus
-
Ji, Y. et al. Validation of antibacterial mechanism of action using regulated antisense RNA expression in Staphylococcus aureus. FEMS Microbiol. Lett. 231, 177-184 (2004).
-
(2004)
FEMS Microbiol. Lett.
, vol.231
, pp. 177-184
-
-
Ji, Y.1
-
7
-
-
0036863098
-
Mechanistic diversity and regulation of Type II fatty acid synthesis
-
Marrakchi, H., Zhang, Y. M. & Rock, C. O. Mechanistic diversity and regulation of Type II fatty acid synthesis. Biochem. Soc. Trans. 30, 1050-1055 (2002).
-
(2002)
Biochem. Soc. Trans.
, vol.30
, pp. 1050-1055
-
-
Marrakchi, H.1
Zhang, Y.M.2
Rock, C.O.3
-
8
-
-
36549008210
-
Isolation and characterization of unsaturated fatty acid auxotrophs of Streptococcus pneumoniae and Streptococcus mutans
-
Altabe, S., Lopez, P. & de Mendoza, D. Isolation and characterization of unsaturated fatty acid auxotrophs of Streptococcus pneumoniae and Streptococcus mutans. J. Bacteriol. 189, 8139-8144 (2007).
-
(2007)
J. Bacteriol.
, vol.189
, pp. 8139-8144
-
-
Altabe, S.1
Lopez, P.2
De Mendoza, D.3
-
9
-
-
39149115737
-
Membrane lipid homeostasis in bacteria
-
Zhang, Y. M. & Rock, C. O. Membrane lipid homeostasis in bacteria. Nature Rev. Microbiol. 6, 222-233 (2008)
-
(2008)
Nature Rev. Microbiol.
, vol.6
, pp. 222-233
-
-
Zhang, Y.M.1
Rock, C.O.2
-
10
-
-
0019763102
-
Cerulenin
-
Omura, S. Cerulenin. Methods Enzymol. 72, 520-532 (1981).
-
(1981)
Methods Enzymol.
, vol.72
, pp. 520-532
-
-
Omura, S.1
-
11
-
-
0034804919
-
Lipid biosynthesis as a target for antibacterial agents
-
Heath, R. J., White, S. W. & Rock, C. O. Lipid biosynthesis as a target for antibacterial agents. Prog. Lipid Res. 40, 467-497 (2001).
-
(2001)
Prog. Lipid Res.
, vol.40
, pp. 467-497
-
-
Heath, R.J.1
White, S.W.2
Rock, C.O.3
-
12
-
-
33744994317
-
Platensimycin is a selective FabF inhibitor with potent antibiotic properties
-
Wang, J. et al. Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature 441, 358-361 (2006).
-
(2006)
Nature
, vol.441
, pp. 358-361
-
-
Wang, J.1
-
13
-
-
34447263022
-
In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea
-
Yum, J. H. et al. In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. Antimicrob. Agents Chemother. 51, 2591-2593 (2007).
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, pp. 2591-2593
-
-
Yum, J.H.1
-
14
-
-
0036783668
-
Discovery of a novel and potent class of FabI-directed antibacterial agents
-
Payne, D. J. et al. Discovery of a novel and potent class of FabI-directed antibacterial agents. Antimicrob. Agents Chemother. 46, 3118-3124 (2002).
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 3118-3124
-
-
Payne, D.J.1
-
15
-
-
33748469322
-
Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid
-
Vilcheze, C. et al. Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid. Nature Med. 12, 1027-1029 (2006).
-
(2006)
Nature Med.
, vol.12
, pp. 1027-1029
-
-
Vilcheze, C.1
|