Abnormal metabolism flexibility in response to high palmitate concentrations in myotubes derived from obese type 2 diabetic patients

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1812, Issue 4, 2011, Pages 423-430

  Kitzmann, Magali ^a,b   Lantier, Louise ^a,b   Hébrard, Sophie ^a,c   Mercier, Jacques ^a,b,d   Foretz, Marc ^a,c   Aguer, Celine ^a,b  

^a INSERM   (France)

^b UNIV MONTPELLIER   (France)

^c INSTITUT COCHIN   (France)

^d LAPEYRONIE HOSPITAL   (France)

Author keywords

Acetyl CoA carboxylase; AMP activated protein kinase; Lipid overflow; Mitochondria; Palmitate beta oxidation

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ACETYL COENZYME A CARBOXYLASE; CITRATE SYNTHASE; CITRININ; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METFORMIN; PALMITIC ACID;

ADULT; AEROBIC METABOLISM; ARTICLE; BIOGENESIS; BODY MASS; CONTROLLED STUDY; DIABETIC OBESITY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FATTY ACID OXIDATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LIPID COMPOSITION; LIPID METABOLISM; LIPID OXIDATION; LIPID STORAGE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MUSCLE BIOPSY; MYOTUBE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ACETYL-COA CARBOXYLASE; AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; HUMANS; HYPOGLYCEMIC AGENTS; LIPID METABOLISM; METFORMIN; MIDDLE AGED; MITOCHONDRIA; MUSCLE FIBERS, SKELETAL; OBESITY; OXIDATION-REDUCTION; PALMITATES; PHOSPHORYLATION; QUADRICEPS MUSCLE; RIBONUCLEOTIDES;

EID: 78951475570     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2010.12.007     Document Type: Article

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