메뉴 건너뛰기




Volumn 1761, Issue 1, 2006, Pages 100-110

Triacylglycerol accumulation is not primarily affected in myotubes established from type 2 diabetic subjects

Author keywords

Glucose metabolism; Insulin resistance; Lipid metabolism; Oleic acid; Palmitic acid; Skeletal muscle; T2D

Indexed keywords

ANTIMYCIN A1; FATTY ACID; GLUCOSE; GLYCOGEN; INSULIN; OLEIC ACID; OLIGOMYCIN; PALMITIC ACID; TRIACYLGLYCEROL;

EID: 33646065654     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2005.12.003     Document Type: Article
Times cited : (30)

References (55)
  • 3
    • 0028091753 scopus 로고
    • Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus
    • Beck-Nielsen H., and Groop L.C. Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus. J. Clin. Invest.. 94 (1994) 1714
    • (1994) J. Clin. Invest.. , vol.94 , pp. 1714
    • Beck-Nielsen, H.1    Groop, L.C.2
  • 6
    • 0035405847 scopus 로고    scopus 로고
    • Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects
    • Boden G., Lebed B., Schatz M., Homko C., and Lemieux S. Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects. Diabetes 50 (2001) 1612
    • (2001) Diabetes , vol.50 , pp. 1612
    • Boden, G.1    Lebed, B.2    Schatz, M.3    Homko, C.4    Lemieux, S.5
  • 7
    • 0021258643 scopus 로고
    • Correlation between muscle glycogen synthase activity and in vivo insulin action in man
    • Bogardus C., Lillioja S., Stone K., and Mott D. Correlation between muscle glycogen synthase activity and in vivo insulin action in man. J. Clin. Invest. 73 (1984) 1185
    • (1984) J. Clin. Invest. , vol.73 , pp. 1185
    • Bogardus, C.1    Lillioja, S.2    Stone, K.3    Mott, D.4
  • 8
    • 0042905763 scopus 로고    scopus 로고
    • Plasmalemmal fatty acid transport is regulated in heart and skeletal muscle by contraction, insulin and leptin, and in obesity and diabetes
    • Bonen A., Benton C.R., Campbell S.E., Chabowski A., Clarke D.C., Han X.X., Glatz J.F., and Luiken J.J. Plasmalemmal fatty acid transport is regulated in heart and skeletal muscle by contraction, insulin and leptin, and in obesity and diabetes. Acta Physiol. Scand. 178 (2003) 347
    • (2003) Acta Physiol. Scand. , vol.178 , pp. 347
    • Bonen, A.1    Benton, C.R.2    Campbell, S.E.3    Chabowski, A.4    Clarke, D.C.5    Han, X.X.6    Glatz, J.F.7    Luiken, J.J.8
  • 9
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248
    • (1976) Anal. Biochem. , vol.72 , pp. 248
    • Bradford, M.M.1
  • 10
    • 0038532298 scopus 로고    scopus 로고
    • A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids
    • Chavez J.A., Knotts T.A., Wang L.P., Li G., Dobrowsky R.T., Florant G.L., and Summers S.A. A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. J. Biol. Chem. 278 (2003) 10297
    • (2003) J. Biol. Chem. , vol.278 , pp. 10297
    • Chavez, J.A.1    Knotts, T.A.2    Wang, L.P.3    Li, G.4    Dobrowsky, R.T.5    Florant, G.L.6    Summers, S.A.7
  • 11
    • 0142164965 scopus 로고    scopus 로고
    • Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes
    • Chavez J.A., and Summers S.A. Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes. Arch. Biochem. Biophys. 419 (2003) 101
    • (2003) Arch. Biochem. Biophys. , vol.419 , pp. 101
    • Chavez, J.A.1    Summers, S.A.2
  • 12
    • 0028799952 scopus 로고
    • Glucose transport in cultured human skeletal muscle cells. Regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects
    • Ciaraldi T.P., Abrams L., Nikoulina S., Mudaliar S., and Henry R.R. Glucose transport in cultured human skeletal muscle cells. Regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects. J. Clin. Invest. 96 (1995) 2820
    • (1995) J. Clin. Invest. , vol.96 , pp. 2820
    • Ciaraldi, T.P.1    Abrams, L.2    Nikoulina, S.3    Mudaliar, S.4    Henry, R.R.5
  • 13
    • 0025860114 scopus 로고
    • Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus
    • Damsbo P., Vaag A., Hother-Nielsen O., and Beck-Nielsen H. Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 34 (1991) 239
    • (1991) Diabetologia , vol.34 , pp. 239
    • Damsbo, P.1    Vaag, A.2    Hother-Nielsen, O.3    Beck-Nielsen, H.4
  • 15
    • 4344701517 scopus 로고    scopus 로고
    • The reduced insulin mediated glucose oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin-evidence from cultured myotubes
    • Gaster M., and Beck-Nielsen H. The reduced insulin mediated glucose oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin-evidence from cultured myotubes. Biochim. Biophys. Acta 1690 (2004) 85
    • (2004) Biochim. Biophys. Acta , vol.1690 , pp. 85
    • Gaster, M.1    Beck-Nielsen, H.2
  • 17
    • 0037542550 scopus 로고    scopus 로고
    • GLUT4 expression in human muscle fibres is not correlated with intracellular triglyceride (TG) content. Is TG a maker or a marker of insulin resistance?
    • Gaster M., Ottosen P.D., Vach W., Christiansen H., Staehr P., Beck-Nielsen H., and Schroder H.D. GLUT4 expression in human muscle fibres is not correlated with intracellular triglyceride (TG) content. Is TG a maker or a marker of insulin resistance?. APMIS 111 (2003) 338
    • (2003) APMIS , vol.111 , pp. 338
    • Gaster, M.1    Ottosen, P.D.2    Vach, W.3    Christiansen, H.4    Staehr, P.5    Beck-Nielsen, H.6    Schroder, H.D.7
  • 18
    • 0036224284 scopus 로고    scopus 로고
    • The diabetic phenotype is conserved in myotubes established from diabetic subjects: evidence for primary defects in glucose transport and glycogen synthase activity
    • Gaster M., Petersen I., Hojlund K., Poulsen P., and Beck-Nielsen H. The diabetic phenotype is conserved in myotubes established from diabetic subjects: evidence for primary defects in glucose transport and glycogen synthase activity. Diabetes 51 (2002) 921
    • (2002) Diabetes , vol.51 , pp. 921
    • Gaster, M.1    Petersen, I.2    Hojlund, K.3    Poulsen, P.4    Beck-Nielsen, H.5
  • 19
    • 14644435061 scopus 로고    scopus 로고
    • Differential utilization of saturated palmitate and unsaturated oleate. Evidence from cultured myotubes
    • Gaster M., Rustan A., and Beck-Nielsen H. Differential utilization of saturated palmitate and unsaturated oleate. Evidence from cultured myotubes. Diabetes 54 (2005) 648
    • (2005) Diabetes , vol.54 , pp. 648
    • Gaster, M.1    Rustan, A.2    Beck-Nielsen, H.3
  • 20
    • 1442326017 scopus 로고    scopus 로고
    • Reduced lipid oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin: evidence from cultured myotubes
    • Gaster M., Rustan A.C., Aas V., and Beck-Nielsen H. Reduced lipid oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin: evidence from cultured myotubes. Diabetes 53 (2004) 542
    • (2004) Diabetes , vol.53 , pp. 542
    • Gaster, M.1    Rustan, A.C.2    Aas, V.3    Beck-Nielsen, H.4
  • 21
    • 0035969561 scopus 로고    scopus 로고
    • The basal kinetic parameters of glycogen synthase in human myotube cultures are not affected by chronic high insulin exposure
    • Gaster M., Schroder H.D., Handberg A., and Beck-Nielsen H. The basal kinetic parameters of glycogen synthase in human myotube cultures are not affected by chronic high insulin exposure. Biochim. Biophys. Acta 1537 (2001) 211
    • (2001) Biochim. Biophys. Acta , vol.1537 , pp. 211
    • Gaster, M.1    Schroder, H.D.2    Handberg, A.3    Beck-Nielsen, H.4
  • 22
    • 0035217707 scopus 로고    scopus 로고
    • Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes
    • Goodpaster B.H., He J., Watkins S., and Kelley D.E. Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes. J. Clin. Endocrinol. Metab 86 (2001) 5755
    • (2001) J. Clin. Endocrinol. Metab , vol.86 , pp. 5755
    • Goodpaster, B.H.1    He, J.2    Watkins, S.3    Kelley, D.E.4
  • 23
    • 0034107084 scopus 로고    scopus 로고
    • Thigh adipose tissue distribution is associated with insulin resistance in obesity and in type 2 diabetes mellitus
    • Goodpaster B.H., Thaete F.L., and Kelley D.E. Thigh adipose tissue distribution is associated with insulin resistance in obesity and in type 2 diabetes mellitus. Am. J. Clin. Nutr. 71 (2000) 885
    • (2000) Am. J. Clin. Nutr. , vol.71 , pp. 885
    • Goodpaster, B.H.1    Thaete, F.L.2    Kelley, D.E.3
  • 24
    • 0030765908 scopus 로고    scopus 로고
    • Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat
    • Goodpaster B.H., Thaete F.L., Simoneau J.A., and Kelley D.E. Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes 46 (1997) 1579
    • (1997) Diabetes , vol.46 , pp. 1579
    • Goodpaster, B.H.1    Thaete, F.L.2    Simoneau, J.A.3    Kelley, D.E.4
  • 26
    • 0035083645 scopus 로고    scopus 로고
    • Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity
    • He J., Watkins S., and Kelley D.E. Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity. Diabetes 50 (2001) 817
    • (2001) Diabetes , vol.50 , pp. 817
    • He, J.1    Watkins, S.2    Kelley, D.E.3
  • 27
    • 0036316341 scopus 로고    scopus 로고
    • Increased efficiency of fatty acid uptake contributes to lipid accumulation in skeletal muscle of high fat-fed insulin-resistant rats
    • Hegarty B.D., Cooney G.J., Kraegen E.W., and Furler S.M. Increased efficiency of fatty acid uptake contributes to lipid accumulation in skeletal muscle of high fat-fed insulin-resistant rats. Diabetes 51 (2002) 1477
    • (2002) Diabetes , vol.51 , pp. 1477
    • Hegarty, B.D.1    Cooney, G.J.2    Kraegen, E.W.3    Furler, S.M.4
  • 28
    • 0042767662 scopus 로고    scopus 로고
    • Effect of training on muscle triacylglycerol and structural lipids: a relation to insulin sensitivity?
    • Helge J.W., and Dela F. Effect of training on muscle triacylglycerol and structural lipids: a relation to insulin sensitivity?. Diabetes 52 (2003) 1881
    • (2003) Diabetes , vol.52 , pp. 1881
    • Helge, J.W.1    Dela, F.2
  • 29
    • 0029739976 scopus 로고    scopus 로고
    • Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms
    • Henry R.R., Ciaraldi T.P., Abrams-Carter L., Mudaliar S., Park K.S., and Nikoulina S.E. Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms. J. Clin. Invest. 98 (1996) 1231
    • (1996) J. Clin. Invest. , vol.98 , pp. 1231
    • Henry, R.R.1    Ciaraldi, T.P.2    Abrams-Carter, L.3    Mudaliar, S.4    Park, K.S.5    Nikoulina, S.E.6
  • 30
    • 0030010373 scopus 로고    scopus 로고
    • Acquired defects of glycogen synthase activity in cultured human skeletal muscle cells: influence of high glucose and insulin levels
    • Henry R.R., Ciaraldi T.P., Mudaliar S., Abrams L., and Nikoulina S.E. Acquired defects of glycogen synthase activity in cultured human skeletal muscle cells: influence of high glucose and insulin levels. Diabetes 45 (1996) 400
    • (1996) Diabetes , vol.45 , pp. 400
    • Henry, R.R.1    Ciaraldi, T.P.2    Mudaliar, S.3    Abrams, L.4    Nikoulina, S.E.5
  • 31
    • 0023493041 scopus 로고
    • Palmitate oxidation and some enzymes of energy metabolism in human muscles and cultured muscle cells
    • Jacobs A.E., Oosterhof A., and Veerkamp J.H. Palmitate oxidation and some enzymes of energy metabolism in human muscles and cultured muscle cells. Int. J. Biochem. 19 (1987) 1049
    • (1987) Int. J. Biochem. , vol.19 , pp. 1049
    • Jacobs, A.E.1    Oosterhof, A.2    Veerkamp, J.H.3
  • 33
    • 0033400310 scopus 로고    scopus 로고
    • Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
    • Kelley D.E., Goodpaster B., Wing R.R., and Simoneau J.A. Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss. Am. J. Physiol. 277 (1999) E1130-E1141
    • (1999) Am. J. Physiol. , vol.277
    • Kelley, D.E.1    Goodpaster, B.2    Wing, R.R.3    Simoneau, J.A.4
  • 34
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • Kelley D.E., He J., Menshikova E.V., and Ritov V.B. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51 (2002) 2944
    • (2002) Diabetes , vol.51 , pp. 2944
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 35
    • 0027218865 scopus 로고
    • Interaction between glucose and free fatty acid metabolism in human skeletal muscle
    • Kelley D.E., Mokan M., Simoneau J.A., and Mandarino L.J. Interaction between glucose and free fatty acid metabolism in human skeletal muscle. J. Clin. Invest. 92 (1993) 91
    • (1993) J. Clin. Invest. , vol.92 , pp. 91
    • Kelley, D.E.1    Mokan, M.2    Simoneau, J.A.3    Mandarino, L.J.4
  • 36
    • 0029962282 scopus 로고    scopus 로고
    • Metabolic impairment precedes insulin resistance in skeletal muscle during high-fat feeding in rats
    • Kim J.K., Wi J.K., and Youn J.H. Metabolic impairment precedes insulin resistance in skeletal muscle during high-fat feeding in rats. Diabetes 45 (1996) 651
    • (1996) Diabetes , vol.45 , pp. 651
    • Kim, J.K.1    Wi, J.K.2    Youn, J.H.3
  • 37
    • 0026040907 scopus 로고
    • Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats
    • Kraegen E.W., Clark P.W., Jenkins A.B., Daley E.A., Chisholm D.J., and Storlien L.H. Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats. Diabetes 40 (1991) 1397
    • (1991) Diabetes , vol.40 , pp. 1397
    • Kraegen, E.W.1    Clark, P.W.2    Jenkins, A.B.3    Daley, E.A.4    Chisholm, D.J.5    Storlien, L.H.6
  • 38
    • 0032934826 scopus 로고    scopus 로고
    • Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study
    • Krssak M., Falk P.K., Dresner A., DiPietro L., Vogel S.M., Rothman D.L., Roden M., and Shulman G.I. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia 42 (1999) 113
    • (1999) Diabetologia , vol.42 , pp. 113
    • Krssak, M.1    Falk, P.K.2    Dresner, A.3    DiPietro, L.4    Vogel, S.M.5    Rothman, D.L.6    Roden, M.7    Shulman, G.I.8
  • 39
    • 0021472102 scopus 로고
    • Quantification of attached cells in microtiter plates based on Coomassie brilliant blue G-250 staining of total cellular protein
    • Laughton C. Quantification of attached cells in microtiter plates based on Coomassie brilliant blue G-250 staining of total cellular protein. Anal. Biochem. 140 (1984) 417
    • (1984) Anal. Biochem. , vol.140 , pp. 417
    • Laughton, C.1
  • 40
    • 0022764258 scopus 로고
    • Measurement of the specific lipid content of attached cells in microtiter cultures
    • Laughton C. Measurement of the specific lipid content of attached cells in microtiter cultures. Anal. Biochem. 156 (1986) 307
    • (1986) Anal. Biochem. , vol.156 , pp. 307
    • Laughton, C.1
  • 41
    • 0034945787 scopus 로고    scopus 로고
    • Morphometric documentation of abnormal intramyocellular fat storage and reduced glycogen in obese patients with Type II diabetes
    • Levin K., Daa S.H., Alford F.P., and Beck-Nielsen H. Morphometric documentation of abnormal intramyocellular fat storage and reduced glycogen in obese patients with Type II diabetes. Diabetologia 44 (2001) 824
    • (2001) Diabetologia , vol.44 , pp. 824
    • Levin, K.1    Daa, S.H.2    Alford, F.P.3    Beck-Nielsen, H.4
  • 43
    • 0030689043 scopus 로고    scopus 로고
    • Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding
    • Oakes N.D., Cooney G.J., Camilleri S., Chisholm D.J., and Kraegen E.W. Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding. Diabetes 46 (1997) 1768
    • (1997) Diabetes , vol.46 , pp. 1768
    • Oakes, N.D.1    Cooney, G.J.2    Camilleri, S.3    Chisholm, D.J.4    Kraegen, E.W.5
  • 44
    • 20444463198 scopus 로고    scopus 로고
    • Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: evidence for an intrinsic oxidative enzyme defect
    • Ortenblad N., Mogensen M., Petersen I., Hojlund K., Levin K., Sahlin K., Beck-Nielsen H., and Gaster M. Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: evidence for an intrinsic oxidative enzyme defect. Biochim. Biophys. Acta 1741 (2005) 206
    • (2005) Biochim. Biophys. Acta , vol.1741 , pp. 206
    • Ortenblad, N.1    Mogensen, M.2    Petersen, I.3    Hojlund, K.4    Levin, K.5    Sahlin, K.6    Beck-Nielsen, H.7    Gaster, M.8
  • 46
    • 3042551249 scopus 로고    scopus 로고
    • Increased Beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid induced insulin resistance despite intramyocellular lipid accumulation
    • Perdomo G., Commerford S.R., Richard A.M., Adams S.H., Corkey B.E., O'Doherty R.M., and Brown N.F. Increased Beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid induced insulin resistance despite intramyocellular lipid accumulation. J. Biol. Chem. 279 26 (2004) 27177-27186
    • (2004) J. Biol. Chem. , vol.279 , Issue.26 , pp. 27177-27186
    • Perdomo, G.1    Commerford, S.R.2    Richard, A.M.3    Adams, S.H.4    Corkey, B.E.5    O'Doherty, R.M.6    Brown, N.F.7
  • 47
    • 0032764784 scopus 로고    scopus 로고
    • Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents
    • Perseghin G., Scifo P., De Cobelli F., Pagliato E., Battezzati A., Arcelloni C., Vanzulli A., Testolin G., Pozza G., Del Maschio A., and Luzi L. Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes 48 (1999) 1600
    • (1999) Diabetes , vol.48 , pp. 1600
    • Perseghin, G.1    Scifo, P.2    De Cobelli, F.3    Pagliato, E.4    Battezzati, A.5    Arcelloni, C.6    Vanzulli, A.7    Testolin, G.8    Pozza, G.9    Del Maschio, A.10    Luzi, L.11
  • 48
    • 1642377274 scopus 로고    scopus 로고
    • Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
    • Petersen K.F., Dufour S., Befroy D., Garcia R., and Shulman G.I. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N. Engl. J. Med. 350 (2004) 664
    • (2004) N. Engl. J. Med. , vol.350 , pp. 664
    • Petersen, K.F.1    Dufour, S.2    Befroy, D.3    Garcia, R.4    Shulman, G.I.5
  • 49
    • 0029787329 scopus 로고    scopus 로고
    • Intramuscular triglyceride and muscle insulin sensitivity: evidence for a relationship in nondiabetic subjects
    • Phillips D.I., Caddy S., Ilic V., Fielding B.A., Frayn K.N., Borthwick A.C., and Taylor R. Intramuscular triglyceride and muscle insulin sensitivity: evidence for a relationship in nondiabetic subjects. Metabolism 45 (1996) 947
    • (1996) Metabolism , vol.45 , pp. 947
    • Phillips, D.I.1    Caddy, S.2    Ilic, V.3    Fielding, B.A.4    Frayn, K.N.5    Borthwick, A.C.6    Taylor, R.7
  • 51
    • 0033588253 scopus 로고    scopus 로고
    • Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate
    • Schmitz-Peiffer C., Craig D.L., and Biden T.J. Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate. J. Biol. Chem. 274 (1999) 24202
    • (1999) J. Biol. Chem. , vol.274 , pp. 24202
    • Schmitz-Peiffer, C.1    Craig, D.L.2    Biden, T.J.3
  • 53
    • 0028987309 scopus 로고
    • Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women
    • Simoneau J.A., Colberg S.R., Thaete F.L., and Kelley D.E. Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women. FASEB J. 9 (1995) 273
    • (1995) FASEB J. , vol.9 , pp. 273
    • Simoneau, J.A.1    Colberg, S.R.2    Thaete, F.L.3    Kelley, D.E.4
  • 54
    • 0030740621 scopus 로고    scopus 로고
    • Altered glycolytic and oxidative capacities of skeletal muscle contribute to insulin resistance in NIDDM
    • Simoneau J.A., and Kelley D.E. Altered glycolytic and oxidative capacities of skeletal muscle contribute to insulin resistance in NIDDM. J. Appl. Physiol. 83 (1997) 166
    • (1997) J. Appl. Physiol. , vol.83 , pp. 166
    • Simoneau, J.A.1    Kelley, D.E.2
  • 55
    • 0028083233 scopus 로고
    • Stimulation of fatty acid oxidation by a 3-thia fatty acid reduces triacylglycerol secretion in cultured rat hepatocytes
    • Skrede S., Bremer J., Berge R.K., and Rustan A.C. Stimulation of fatty acid oxidation by a 3-thia fatty acid reduces triacylglycerol secretion in cultured rat hepatocytes. J. Lipid Res. 35 (1994) 1395
    • (1994) J. Lipid Res. , vol.35 , pp. 1395
    • Skrede, S.1    Bremer, J.2    Berge, R.K.3    Rustan, A.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.