Transcriptional profiling of myotubes from patients with type 2 diabetes: No evidence for a primary defect in oxidative phosphorylation genes

Diabetologia

Volumn 51, Issue 11, 2008, Pages 2068-2077

  Frederiksen, C M ^a   Hojlund K ^a   Hansen, L ^b   Oakeley, E J ^c   Hemmings, B ^c   Abdallah, B M ^a,d   Brusgaard, K ^a   Beck Nielsen, H ^a   Gaster, M ^a  

^a ODENSE UNIVERSITY HOSPITAL   (Denmark)

^b STENO DIABETES CENTER   (Denmark)

^c FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^d UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Cell culture; Genetics; Microarray; Oxidative phosphorylation; Skeletal muscle; Type 2 diabetes

Indexed keywords

MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRANSCRIPTION FACTOR NRF1;

ADULT; ARTICLE; BIOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETOGENESIS; DNA MICROARRAY; GENE EXPRESSION; GLUCOSE OXIDATION; GLYCOGEN SYNTHESIS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; LIPID OXIDATION; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL VOLUME; MYOTUBE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; GENE EXPRESSION PROFILING; HEAT-SHOCK PROTEINS; HUMANS; MIDDLE AGED; MUSCLE FIBERS; MUSCLE, SKELETAL; NUCLEAR RESPIRATORY FACTOR 1; OBESITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE PHOSPHORYLATION; RNA; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 53549085136     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-008-1122-9     Document Type: Article

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