Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: Evidence for an intrinsic oxidative enzyme defect

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1741, Issue 1-2, 2005, Pages 206-214

  Ørtenblad, Niels ^a   Mogensen, Martin ^a   Petersen, Ingrid ^b   Højlund, Kurt ^b   Levin, Klaus ^b   Sahlin, Kent ^a   Beck Nielsen, Henning ^b   Gaster, Michael ^b  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Citrate synthase; Free fatty acid; Insulin resistance; Myotube; Obese; Type 2 diabetes; Uncoupled respiration

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; CITRATE SYNTHASE; FATTY ACID; INSULIN; OXIDOREDUCTASE; PALMITIC ACID;

ADULT; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFECT; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; INCUBATION TIME; INSULIN RESISTANCE; LEAN BODY WEIGHT; MITOCHONDRIAL RESPIRATION; MUSCLE CELL; MYOTUBE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PATHOGENESIS; PRIORITY JOURNAL; SKELETAL MUSCLE;

3-HYDROXYACYL COA DEHYDROGENASES; CELLS, CULTURED; CITRATE (SI)-SYNTHASE; DIABETES MELLITUS, TYPE 2; GLUCOSE; HUMANS; INSULIN; INSULIN RESISTANCE; MIDDLE AGED; MUSCLE FIBERS; MUSCLE, SKELETAL; OBESITY; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; PALMITIC ACID;

EID: 20444463198     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2005.04.001     Document Type: Article

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