Berberine sensitizes TRAIL-induced apoptosis through proteasome-mediated downregulation of c-FLIP and Mcl-1 proteins

International Journal of Oncology

Volumn 38, Issue 2, 2011, Pages 485-492

  Lee, Sung Jun ^a   Noh, Hyo Jeong ^a   Sung, Eon Gi ^a   Song, In Hwan ^a   Kim, Joo Young ^a   Kwon, Taeg Kyu ^b   Lee, Tae Jin ^a  

^a Yeungnam University College of Medicine   (South Korea)

^b Keimyung University   (South Korea)

Author keywords

Berberine; c FLIP; Mcl 1; Proteasome; ROS; TRAIL

Indexed keywords

ACETYLCYSTEINE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BERBERINE; FLICE INHIBITORY PROTEIN; PROTEASOME; PROTEIN MCL 1; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CANCER CELL; CELL DEATH; DOWN REGULATION; DRUG MECHANISM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; BERBERINE; BLOTTING, WESTERN; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; FLOW CYTOMETRY; HUMANS; KIDNEY NEOPLASMS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 78651254850     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2010.878     Document Type: Article

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