BBR induces apoptosis in HepG2 cell through an Akt-ASK1-ROS-p38MAPKS-linked cascade

Journal of Cellular Biochemistry

Volumn 109, Issue 2, 2010, Pages 329-338

  Hyun, Mee Sun ^a   Hur, Jung Mu ^b   Mun, Yeun Ja ^a   Kim, Dongho ^b   Woo, Won Hong ^a  

^a Wonkwang University   (South Korea)

^b Korea Atomic Energy Research Institute   (South Korea)

Author keywords

Akt; Apoptosis; ASK1; Berberine; p38; ROS

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; APOPTOSIS SIGNAL REGULATING KINASE 1; BERBERINE; CASPASE 3; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE P38; PROCASPASE 3; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P53; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANNEXIN A5; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BERBERINE; CASPASE 3; DNA FRAGMENTATION; HEP G2 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE KINASE 5; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

FUNGI;

EID: 74949087380     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22384     Document Type: Article

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