Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells

Oncogene

Volumn 20, Issue 37, 2001, Pages 5225-5231

  Fukazawa, Takuya ^a   Fujiwara, Toshiyoshi ^a   Uno, Futoshi ^a   Teraishi, Fuminori ^a   Kadowaki, Yoshihiko ^a   Itoshima, Takahiro ^b   Takata, Yoshiko ^a   Kagawa, Shunsuke ^c   Roth, Jack A ^c   Tschopp, Jürg ^d   Tanaka, Noriaki ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Apoptosis; Colon cancer; FLIP; P53; Ubiquitin proteasome

Indexed keywords

FLICE INHIBITORY PROTEIN; PROTEASOME; PROTEIN P53; UBIQUITIN;

APOPTOSIS; ARTICLE; CANCER CELL; CELL STIMULATION; COLON CANCER; CONTROLLED STUDY; GENE TRANSFER; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SENSITIZATION; SUICIDE GENE;

ADENOVIRIDAE; APOPTOSIS; CARRIER PROTEINS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL DIVISION; CYSTEINE ENDOPEPTIDASES; DOWN-REGULATION; GENE TRANSFER TECHNIQUES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; TIME FACTORS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINS;

EID: 17944373682     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1204673     Document Type: Article

References (23)