Molecular biology and pathology of prion strains in sporadic human prion diseases

Acta Neuropathologica

Volumn 121, Issue 1, 2011, Pages 79-90

  Gambetti, Pierluigi ^a   Cali, Ignazio ^a   Notari, Silvio ^a   Kong, Qingzhong ^a   Zou, Wen Quan ^a   Surewicz, Witold K ^b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

129 polymorphism; Creutzfeldt Jakob disease; PrP sequencing; PrPSc type; Sporadic fatal insomnia; Variably protease sensitive prionopathy

Indexed keywords

ASPARAGINE; ASPARTIC ACID; ISOPROTEIN; METHIONINE; PRION PROTEIN; VALINE;

ALLELE; AMINO ACID SUBSTITUTION; BRAIN DISEASE; CODON; DISEASE TRANSMISSION; DNA POLYMORPHISM; ELECTROPHORETIC MOBILITY; FATAL FAMILIAL INSOMNIA; GENE FUNCTION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC CODE; GENETIC RISK; GENETIC STRAIN; GENETIC SUSCEPTIBILITY; GENOTYPE PHENOTYPE CORRELATION; HETEROZYGOTE; HISTOPATHOLOGY; HOMOZYGOTE; HUMAN; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NONHUMAN; ONSET AGE; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DEFECT; PROTEIN FOLDING; PROTEIN LOCALIZATION; REVIEW; SEQUENCE ANALYSIS; SPORADIC CREUTZFELDT JAKOB DISEASE; VARIABLY PROTEASE SENSITIVE PRIONOPATHY;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; PRION DISEASES; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN ISOFORMS; PRPC PROTEINS; PRPSC PROTEINS;

EID: 78651240044     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-010-0761-3     Document Type: Review

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