Polymorphism at residue 129 modulates the conformational conversion of the D178N variant of human prion protein 90-231

Biochemistry

Volumn 44, Issue 48, 2005, Pages 15880-15888

  Apetri, Adrian C ^a   Vanik, David L ^a   Surewicz, Witold K ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CONFORMATIONS; DISEASES; GENES; MUTAGENESIS; PH EFFECTS;

BIOPHYSICAL PROPERTIES; MUTATIONS; POLYMORPHISM; SPONGIFORM ENCEPHALOPATHIES;

PROTEINS;

AMYLOID; ASPARAGINE; ASPARTIC ACID; METHIONINE; OLIGOMER; PRION PROTEIN; THIOFLAVINE; VALINE;

ARTICLE; BETA SHEET; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GENE; GENE MUTATION; GENETIC POLYMORPHISM; HUMAN; PRION DISEASE; PRIORITY JOURNAL; PRNP GENE; PROTEIN SECONDARY STRUCTURE;

AMYLOID; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ATOMIC FORCE; PEPTIDE FRAGMENTS; POLYMORPHISM, GENETIC; PRION DISEASES; PRIONS; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THERMODYNAMICS;

EID: 28544443624     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051455+     Document Type: Article

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