Altered glycosylated PrP proteins can have different neuronal trafficking in brain but do not acquire scrapie-like properties

Journal of Biological Chemistry

Volumn 280, Issue 52, 2005, Pages 42909-42918

  Cancellotti, Enrico ^a,b   Wiseman, Frances ^a   Tuzi, Nadia L ^a   Baybutt, Herbert ^a   Monaghan, Paul ^a   Aitchison, Lorraine ^a   Simpson, Jennifer ^a   Manson, Jean C ^a  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CELL CULTURE; NEUROLOGY; PATHOLOGY;

CELL MEMBRANE; ENCEPHALOPATHY; GLYCOPROTEINS;

PROTEINS;

ASPARAGINE; GLYCAN; PRION PROTEIN; THREONINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DISEASE MODEL; DISEASE PREDISPOSITION; EMBRYO; GENE TARGETING; MOUSE; NONHUMAN; PHENOTYPE; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN STABILITY; PROTEIN TRANSPORT; TRANSGENIC MOUSE;

AGING; ALLELES; ANIMALS; ANTIBODIES, MONOCLONAL; ASPARAGINE; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; BLOTTING, WESTERN; BRAIN; CARBOHYDRATES; CELL MEMBRANE; CELLS, CULTURED; DETERGENTS; DISEASE MODELS, ANIMAL; DNA; EMBRYO; ENDOPEPTIDASE K; ENDOPLASMIC RETICULUM; FEMALE; GENETIC VECTORS; GENOTYPE; GLYCOPROTEINS; GLYCOSYLATION; GOLGI APPARATUS; HOMOZYGOTE; IMMUNOHISTOCHEMISTRY; MALE; MANNOSYL-GLYCOPROTEIN ENDO-BETA-N-ACETYLGLUCOSAMINIDASE; MICE; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; MODELS, GENETIC; MUTATION; NEURONS; PHENOTYPE; PHOSPHOLIPASE C; POLYMERASE CHAIN REACTION; POLYSACCHARIDES; PRIONS; RECOMBINATION, GENETIC; RNA; RNA, MESSENGER; SCRAPIE; SOLUBILITY; STEM CELLS; THREONINE; TIME FACTORS;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 30044434667     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M509557200     Document Type: Article

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