-
1
-
-
0028325311
-
Helicobacter hepaticus sp. nov., A microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice
-
Fox, J. G. et al. Helicobacter hepaticus sp. nov., a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice. J. Clin. Microbiol. 32, 1238-1245 (1994).
-
(1994)
J. Clin. Microbiol.
, vol.32
, pp. 1238-1245
-
-
Fox, J.G.1
-
2
-
-
0028093372
-
Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species
-
Ward, J. M. et al. Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species. J. Natl Cancer. Inst. 86, 1222-1227 (1994).
-
(1994)
J. Natl Cancer. Inst.
, vol.86
, pp. 1222-1227
-
-
Ward, J.M.1
-
3
-
-
0029986919
-
Chronic proliferative hepatitis in A/JCr mice associated with persistent Helicobacter hepaticus infection: A model of Helicobacter-induced carcinogenesis
-
Fox, J. G. et al. Chronic proliferative hepatitis in A/JCr mice associated with persistent Helicobacter hepaticus infection: A model of Helicobacter-induced carcinogenesis. Infect. Immun. 64, 1548-1558 (1996).
-
(1996)
Infect. Immun.
, vol.64
, pp. 1548-1558
-
-
Fox, J.G.1
-
4
-
-
77951830706
-
Helicobacter pullorum outbreak in C57BL/6NTac and C3H/HeNTac barrier-maintained mice
-
Boutin, S. R. et al. Helicobacter pullorum outbreak in C57BL/6NTac and C3H/HeNTac barrier-maintained mice. J. Clin. Microbiol. 48, 1908-1910 (2010).
-
(2010)
J. Clin. Microbiol.
, vol.48
, pp. 1908-1910
-
-
Boutin, S.R.1
-
5
-
-
0028864668
-
Identifi cation of widespread Helicobacter hepaticus infection in feces in commercial mouse colonies by culture and PCR assay
-
Shames, B. et al. Identifi cation of widespread Helicobacter hepaticus infection in feces in commercial mouse colonies by culture and PCR assay. J. Clin. Microbiol. 33, 2968-2972 (1995).
-
(1995)
J. Clin. Microbiol.
, vol.33
, pp. 2968-2972
-
-
Shames, B.1
-
6
-
-
34547645764
-
Enterohepatic Helicobacter species are prevalent in mice from commercial and academic institutions in Asia, Europe, and North America
-
Taylor, N. S., Xu, S., Nambiar, P., Dewhirst, F. E. & Fox, J. G. Enterohepatic Helicobacter species are prevalent in mice from commercial and academic institutions in Asia, Europe, and North America. J. Clin. Microbiol. 45, 2166-2172 (2007).
-
(2007)
J. Clin. Microbiol.
, vol.45
, pp. 2166-2172
-
-
Taylor, N.S.1
Xu, S.2
Nambiar, P.3
Dewhirst, F.E.4
Fox, J.G.5
-
7
-
-
0029813545
-
Enterocolitis and colon cancer in interleukin-10-defi cient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses
-
Berg, D. J. et al. Enterocolitis and colon cancer in interleukin-10-defi cient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses. J. Clin. Invest. 98, 1010-1020 (1996).
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1010-1020
-
-
Berg, D.J.1
-
8
-
-
0029873909
-
Infl ammatory large bowel disease in immunodefi cient mice naturally infected with Helicobacter hepaticus
-
Ward, J. M. et al. Infl ammatory large bowel disease in immunodefi cient mice naturally infected with Helicobacter hepaticus. Lab. Anim. Sci. 46, 15-20 (1996).
-
(1996)
Lab. Anim. Sci.
, vol.46
, pp. 15-20
-
-
Ward, J.M.1
-
9
-
-
0032090186
-
Spontaneous infl ammatory bowel disease in multiple mutant mouse lines: Association with colonization by Helicobacter hepaticus
-
Foltz, C. J. et al. Spontaneous infl ammatory bowel disease in multiple mutant mouse lines: Association with colonization by Helicobacter hepaticus. Helicobacter 3, 69-78 (1998).
-
(1998)
Helicobacter
, vol.3
, pp. 69-78
-
-
Foltz, C.J.1
-
10
-
-
0030794060
-
Infl ammatory bowel disease: An immunity-mediated condition triggered by bacterial infection with Helicobacter hepaticus
-
Cahill, R. J. et al. Infl ammatory bowel disease: An immunity-mediated condition triggered by bacterial infection with Helicobacter hepaticus. Infect Immun 65, 3126-3131 (1997).
-
(1997)
Infect Immun
, vol.65
, pp. 3126-3131
-
-
Cahill, R.J.1
-
11
-
-
0027517545
-
Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal infl ammation in C. B-17 scid mice
-
Powrie, F., Leach, M. W., Mauze, S., Caddle, L. B. & Coffman, R. L. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal infl ammation in C. B-17 scid mice. Int. Immunol. 5, 1461-1471 (1993).
-
(1993)
Int. Immunol.
, vol.5
, pp. 1461-1471
-
-
Powrie, F.1
Leach, M.W.2
Mauze, S.3
Caddle, L.B.4
Coffman, R.L.5
-
12
-
-
0028519015
-
Inhibition of Th1 responses prevents infl ammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells
-
Powrie, F. et al. Inhibition of Th1 responses prevents infl ammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells. Immunity 1, 553-562 (1994).
-
(1994)
Immunity
, vol.1
, pp. 553-562
-
-
Powrie, F.1
-
13
-
-
0032425062
-
Helicobacter hepaticus triggers colitis in specifi cpathogen- free interleukin-10 (IL-10)-defi cient mice through an IL-12- and gamma interferon-dependent mechanism
-
Kullberg, M. C. et al. Helicobacter hepaticus triggers colitis in specifi cpathogen- free interleukin-10 (IL-10)-defi cient mice through an IL-12- and gamma interferon-dependent mechanism. Infect. Immun. 66, 5157-5166 (1998).
-
(1998)
Infect. Immun.
, vol.66
, pp. 5157-5166
-
-
Kullberg, M.C.1
-
14
-
-
0034828657
-
Helicobacter-induced infl ammatory bowel disease in IL-10- and T cell-defi cient mice
-
Burich, A. et al. Helicobacter-induced infl ammatory bowel disease in IL-10- and T cell-defi cient mice. Am. J. Physiol. Gastrointest. Liver Physiol. 281, G764-778 (2001).
-
(2001)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.281
-
-
Burich, A.1
-
15
-
-
78650814147
-
Susceptibility of three strains of Rag2-defi cient mice to Helicobacter hepaticus induced colitis and colorectal cancer
-
Erdman, S. E., Poutahidis, T., Rogers, A. B., Tomszaki, M., Horwitz, B. & Fox, J. G. Susceptibility of three strains of Rag2-defi cient mice to Helicobacter hepaticus induced colitis and colorectal cancer. Gastroenterology 124 (Suppl 1), A340 (2003).
-
(2003)
Gastroenterology
, vol.124
, Issue.SUPPL. 1
-
-
Erdman, S.E.1
Poutahidis, T.2
Rogers, A.B.3
Tomszaki, M.4
Horwitz, B.5
Fox, J.G.6
-
16
-
-
0027521572
-
Interleukin- 10-defi cient mice develop chronic enterocolitis
-
Kuhn, R., Lohler, J., Rennick, D., Rajewsky, K. & Muller, W. Interleukin- 10-defi cient mice develop chronic enterocolitis. Cell 75, 263-274 (1993).
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
17
-
-
0033860659
-
Helicobacter hepaticus does not induce or potentiate colitis in interleukin-10-defi cient mice
-
Dieleman, L. A. et al. Helicobacter hepaticus does not induce or potentiate colitis in interleukin-10-defi cient mice. Infect. Immun. 68, 5107-5113 (2000).
-
(2000)
Infect. Immun.
, vol.68
, pp. 5107-5113
-
-
Dieleman, L.A.1
-
18
-
-
0034972172
-
Helicobacter hepaticus -induced colitis in interleukin- 10-defi cient mice: Cytokine requirements for the induction and maintenance of intestinal infl ammation
-
Kullberg, M. C. et al. Helicobacter hepaticus -induced colitis in interleukin- 10-defi cient mice: Cytokine requirements for the induction and maintenance of intestinal infl ammation. Infect. Immun. 69, 4232-4241 (2001).
-
(2001)
Infect. Immun.
, vol.69
, pp. 4232-4241
-
-
Kullberg, M.C.1
-
19
-
-
33750530394
-
IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis
-
Kullberg, M. C. et al. IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. J. Exp. Med. 203, 2485-2494 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2485-2494
-
-
Kullberg, M.C.1
-
20
-
-
59849114998
-
ROR gamma-expressing Th17 cells induce murine chronic intestinal infl ammation via redundant effects of IL-17A and IL-17F
-
Leppkes, M. et al. ROR gamma-expressing Th17 cells induce murine chronic intestinal infl ammation via redundant effects of IL-17A and IL-17F. Gastroenterology 136, 257-267 (2009).
-
(2009)
Gastroenterology
, vol.136
, pp. 257-267
-
-
Leppkes, M.1
-
21
-
-
65749091607
-
A protective function for interleukin 17A in T cell-mediated intestinal infl ammation
-
O'Connor, W. Jr et al. A protective function for interleukin 17A in T cell-mediated intestinal infl ammation. Nat. Immunol. 1, 603-609 (2009).
-
(2009)
Nat. Immunol.
, vol.1
, pp. 603-609
-
-
O'Connor Jr., W.1
-
22
-
-
57449090428
-
Innate and adaptive interleukin-22 protects mice from infl ammatory bowel disease
-
Zenewicz, L. A. et al. Innate and adaptive interleukin-22 protects mice from infl ammatory bowel disease. Immunity 29, 947-957 (2008).
-
(2008)
Immunity
, vol.29
, pp. 947-957
-
-
Zenewicz, L.A.1
-
23
-
-
38849141814
-
IL-22 ameliorates intestinal infl ammation in a mouse model of ulcerative colitis
-
Sugimoto, K. et al. IL-22 ameliorates intestinal infl ammation in a mouse model of ulcerative colitis. J. Clin. Invest. 118, 534-544 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 534-544
-
-
Sugimoto, K.1
-
24
-
-
0141731259
-
CD4(+)CD25(+) regulatory lymphocytes require interleukin 10 to interrupt colon carcinogenesis in mice
-
Erdman, S. E. et al. CD4(+)CD25(+) regulatory lymphocytes require interleukin 10 to interrupt colon carcinogenesis in mice. Cancer Res. 63, 6042-6050 (2003).
-
(2003)
Cancer Res.
, vol.63
, pp. 6042-6050
-
-
Erdman, S.E.1
-
25
-
-
0037243827
-
CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
-
Maloy, K. J. et al. CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J. Exp. Med. 197, 111-119 (2003).
-
(2003)
J. Exp. Med.
, vol.197
, pp. 111-119
-
-
Maloy, K.J.1
-
26
-
-
0042847143
-
NF-kappa B is required within the innate immune system to inhibit microfl ora-induced colitis and expression of IL-12 p40
-
Tomczak, M. F. et al. NF-kappa B is required within the innate immune system to inhibit microfl ora-induced colitis and expression of IL-12 p40. J. Immunol. 171, 1484-1492 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 1484-1492
-
-
Tomczak, M.F.1
-
27
-
-
0032533480
-
IL-7 defi ciency prevents development of a non- T cell non-B cell-mediated colitis
-
von Freeden-Jeffry, U. et al. IL-7 defi ciency prevents development of a non- T cell non-B cell-mediated colitis. J. Immunol. 161, 5673-5680 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 5673-5680
-
-
Von Freeden-Jeffry, U.1
-
28
-
-
0037331279
-
CD4+ CD25+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-defi cient mice
-
Erdman, S. E. et al. CD4+ CD25+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-defi cient mice. Am. J. Pathol. 162, 691-702 (2003).
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 691-702
-
-
Erdman, S.E.1
-
29
-
-
33750505009
-
Interleukin-23 drives innate and T cell-mediated intestinal infl ammation
-
Hue, S. et al. Interleukin-23 drives innate and T cell-mediated intestinal infl ammation. J. Exp. Med. 203, 2473-2483 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2473-2483
-
-
Hue, S.1
-
30
-
-
77951878587
-
Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
-
Buonocore, S. et al. Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. Nature 464, 1371-1375 (2010).
-
(2010)
Nature
, vol.464
, pp. 1371-1375
-
-
Buonocore, S.1
-
31
-
-
3042720708
-
Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells
-
Eberl, G. & Littman, D. R. Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells. Science 305, 248-251 (2004).
-
(2004)
Science
, vol.305
, pp. 248-251
-
-
Eberl, G.1
Littman, D.R.2
-
32
-
-
0346496018
-
An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells
-
Eberl, G. et al. An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat. Immunol. 5, 64-73 (2004).
-
(2004)
Nat. Immunol.
, vol.5
, pp. 64-73
-
-
Eberl, G.1
-
33
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinfl ammatory IL-17+ T helper cells
-
Ivanov, I.I. et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinfl ammatory IL-17+ T helper cells. Cell 126, 1121-1133 (2006).
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
-
34
-
-
0031984960
-
Essential role of IL-7 receptor alpha in the formation of Peyer's patch anlage
-
Adachi, S. et al. Essential role of IL-7 receptor alpha in the formation of Peyer's patch anlage. Int. Immunol. 10, 1-6 (1998).
-
(1998)
Int. Immunol.
, vol.10
, pp. 1-6
-
-
Adachi, S.1
-
35
-
-
14744270856
-
Cure of innate intestinal immune pathology by CD4+CD25+ regulatory T cells
-
Maloy, K. J., Antonelli, L. R., Lefevre, M. & Powrie, F. Cure of innate intestinal immune pathology by CD4+CD25+ regulatory T cells. Immunol. Lett. 97, 189-192 (2005).
-
(2005)
Immunol. Lett.
, vol.97
, pp. 189-192
-
-
Maloy, K.J.1
Antonelli, L.R.2
Lefevre, M.3
Powrie, F.4
-
36
-
-
0037136284
-
Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus -induced colitis
-
Kullberg, M. C. et al. Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus -induced colitis. J. Exp. Med. 196, 505-515 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, pp. 505-515
-
-
Kullberg, M.C.1
-
37
-
-
36949006791
-
Rapid reversal of interleukin-6-dependent epithelial invasion in a mouse model of microbially induced colon carcinoma
-
Poutahidis, T. et al. Rapid reversal of interleukin-6-dependent epithelial invasion in a mouse model of microbially induced colon carcinoma. Carcinogenesis 28, 2614-2623 (2007).
-
(2007)
Carcinogenesis
, vol.28
, pp. 2614-2623
-
-
Poutahidis, T.1
-
38
-
-
30744448978
-
Defective activation of ERK in macrophages lacking the p50/p105 subunit of NF-kappaB is responsible for elevated expression of IL-12 p40 observed after challenge with Helicobacter hepaticus
-
Tomczak, M. F. et al. Defective activation of ERK in macrophages lacking the p50/p105 subunit of NF-kappaB is responsible for elevated expression of IL-12 p40 observed after challenge with Helicobacter hepaticus. J. Immunol. 176, 1244-1251 (2006).
-
(2006)
J. Immunol.
, vol.176
, pp. 1244-1251
-
-
Tomczak, M.F.1
-
39
-
-
50949094396
-
C-Rel is essential for the development of innate and T cellinduced colitis
-
Wang, Y. et al. c-Rel is essential for the development of innate and T cellinduced colitis. J. Immunol. 180, 8118-8125 (2008).
-
(2008)
J. Immunol.
, vol.180
, pp. 8118-8125
-
-
Wang, Y.1
-
40
-
-
33750838717
-
Inhibition of Helicobacter hepaticus -induced colitis by IL-10 requires the p50/p105 subunit of NF-kappa B
-
Tomczak, M. F. et al. Inhibition of Helicobacter hepaticus -induced colitis by IL-10 requires the p50/p105 subunit of NF-kappa B. J. Immunol. 177, 7332-7339 (2006).
-
(2006)
J. Immunol.
, vol.177
, pp. 7332-7339
-
-
Tomczak, M.F.1
-
41
-
-
5044240576
-
Intact gram-negative Helicobacter pylori, Helicobacter felis, and Helicobacter hepaticus bacteria activate innate immunity via tolllike receptor 2 but not toll-like receptor 4
-
Mandell, L. et al. Intact gram-negative Helicobacter pylori, Helicobacter felis, and Helicobacter hepaticus bacteria activate innate immunity via tolllike receptor 2 but not toll-like receptor 4. Infect. Immun. 72, 6446-6454 (2004).
-
(2004)
Infect. Immun.
, vol.72
, pp. 6446-6454
-
-
Mandell, L.1
-
42
-
-
75149118945
-
TLR2-independent induction and regulation of chronic intestinal infl ammation
-
Boulard, O., Asquith, M. J., Powrie, F. & Maloy, K. J. TLR2-independent induction and regulation of chronic intestinal infl ammation. Eur. J. Immunol. 40, 516-524 (2009).
-
(2009)
Eur. J. Immunol.
, vol.40
, pp. 516-524
-
-
Boulard, O.1
Asquith, M.J.2
Powrie, F.3
Maloy, K.J.4
-
43
-
-
77955346494
-
Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of infl ammatory bowel disease
-
Asquith, M. J., Boulard, O., Powrie, F. & Maloy, K. J. Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of infl ammatory bowel disease. Gastroenterology 139, 519-529 (2010).
-
(2010)
Gastroenterology
, vol.139
, pp. 519-529
-
-
Asquith, M.J.1
Boulard, O.2
Powrie, F.3
Maloy, K.J.4
-
44
-
-
33846330896
-
Nod-like proteins in immunity, infl ammation and disease
-
Fritz, J. H., Ferrero, R. L., Philpott, D. J. & Girardin, S. E. Nod-like proteins in immunity, infl ammation and disease. Nat. Immunol. 7, 1250-1257 (2006).
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1250-1257
-
-
Fritz, J.H.1
Ferrero, R.L.2
Philpott, D.J.3
Girardin, S.E.4
-
45
-
-
77954607064
-
A pathobiont of the microbiota balances host colonization and intestinal infl ammation
-
Chow, J. & Mazmanian, S. K. A pathobiont of the microbiota balances host colonization and intestinal infl ammation. Cell Host Microbe 7, 265-276 (2010).
-
(2010)
Cell Host Microbe
, vol.7
, pp. 265-276
-
-
Chow, J.1
Mazmanian, S.K.2
-
46
-
-
65549116380
-
A commensal Helicobacter sp. of the rodent intestinal fl ora activates TLR2 and NOD1 responses in epithelial cells
-
Chaouche-Drider, N. et al. A commensal Helicobacter sp. of the rodent intestinal fl ora activates TLR2 and NOD1 responses in epithelial cells. PLoS One 4, e5396 (2009).
-
(2009)
PLoS One
, vol.4
-
-
Chaouche-Drider, N.1
-
47
-
-
34249905600
-
Inhibitory effect of enterohepatic Helicobacter hepaticus on innate immune responses of mouse intestinal epithelial cells
-
Sterzenbach, T. et al. Inhibitory effect of enterohepatic Helicobacter hepaticus on innate immune responses of mouse intestinal epithelial cells. Infect. Immun. 75, 2717-2728 (2007).
-
(2007)
Infect. Immun.
, vol.75
, pp. 2717-2728
-
-
Sterzenbach, T.1
-
48
-
-
70349468054
-
Nod2 is required for the regulation of commensal microbiota in the intestine
-
Petnicki-Ocwieja, T. et al. Nod2 is required for the regulation of commensal microbiota in the intestine. Proc. Natl Acad. Sci. USA 106, 15813-15818 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 15813-15818
-
-
Petnicki-Ocwieja, T.1
-
49
-
-
42949091932
-
Genetic susceptibility to chronic hepatitis is inherited codominantly in Helicobacter hepaticus -infected AB6F1 and B6AF1 hybrid male mice, and progression to hepatocellular carcinoma is linked to hepatic expression of lipogenic genes and immune function-associated networks
-
Garcia, A. et al. Genetic susceptibility to chronic hepatitis is inherited codominantly in Helicobacter hepaticus -infected AB6F1 and B6AF1 hybrid male mice, and progression to hepatocellular carcinoma is linked to hepatic expression of lipogenic genes and immune function-associated networks. Infect. Immun. 76, 1866-1876 (2008).
-
(2008)
Infect. Immun.
, vol.76
, pp. 1866-1876
-
-
Garcia, A.1
-
50
-
-
0032777440
-
Differential susceptibility to hepatic infl ammation and proliferation in AXB recombinant inbred mice chronically infected with Helicobacter hepaticus
-
Ihrig, M., Schrenzel, M. D. & Fox, J. G. Differential susceptibility to hepatic infl ammation and proliferation in AXB recombinant inbred mice chronically infected with Helicobacter hepaticus. Am. J. Pathol. 155, 571-582 (1999).
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 571-582
-
-
Ihrig, M.1
Schrenzel, M.D.2
Fox, J.G.3
-
51
-
-
0027988869
-
Chronic active hepatitis in mice caused by Helicobacter hepaticus
-
Ward, J. M., Anver, M. R., Haines, D. C. & Benveniste, R. E. Chronic active hepatitis in mice caused by Helicobacter hepaticus. Am. J. Pathol. 145, 959-968 (1994).
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 959-968
-
-
Ward, J.M.1
Anver, M.R.2
Haines, D.C.3
Benveniste, R.E.4
-
52
-
-
73449143207
-
Gut microbes defi ne liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens
-
Fox, J. G. et al. Gut microbes defi ne liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens. Gut 59, 88-97 (2010).
-
(2010)
Gut
, vol.59
, pp. 88-97
-
-
Fox, J.G.1
-
53
-
-
0037112436
-
Elimination of colon cancer in germ-free transforming growth factor beta 1-defi cient mice
-
Engle, S. J. et al. Elimination of colon cancer in germ-free transforming growth factor beta 1-defi cient mice. Cancer Res. 62, 6362-6366 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 6362-6366
-
-
Engle, S.J.1
-
54
-
-
0037370137
-
Pathology of mouse models of intestinal cancer: Consensus report and recommendations
-
Boivin, G. P. et al. Pathology of mouse models of intestinal cancer: Consensus report and recommendations. Gastroenterology 124, 762-777 (2003).
-
(2003)
Gastroenterology
, vol.124
, pp. 762-777
-
-
Boivin, G.P.1
-
55
-
-
0021017589
-
Dysplasia in infl ammatory bowel disease: Standardized classifi cation with provisional clinical applications
-
Riddell, R. H. et al. Dysplasia in infl ammatory bowel disease: Standardized classifi cation with provisional clinical applications. Hum. Pathol. 14, 931-968 (1983).
-
(1983)
Hum. Pathol.
, vol.14
, pp. 931-968
-
-
Riddell, R.H.1
-
56
-
-
59049099999
-
Nitric oxide and TNF-alpha trigger colonic infl ammation and carcinogenesis in Helicobacter hepaticus -infected, Rag2-defi cient mice
-
Erdman, S. E. et al. Nitric oxide and TNF-alpha trigger colonic infl ammation and carcinogenesis in Helicobacter hepaticus -infected, Rag2-defi cient mice. Proc. Natl Acad. Sci. USA 106, 1027-1032 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 1027-1032
-
-
Erdman, S.E.1
-
57
-
-
33747481384
-
Innate immune infl ammatory response against enteric bacteria Helicobacter hepaticus induces mammary adenocarcinoma in mice
-
Rao, V. P. et al. Innate immune infl ammatory response against enteric bacteria Helicobacter hepaticus induces mammary adenocarcinoma in mice. Cancer Res. 66, 7395-7400 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 7395-7400
-
-
Rao, V.P.1
-
58
-
-
0025015168
-
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
-
Moser, A. R., Pitot, H. C. & Dove, W. F. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247, 322-324 (1990).
-
(1990)
Science
, vol.247
, pp. 322-324
-
-
Moser, A.R.1
Pitot, H.C.2
Dove, W.F.3
-
59
-
-
20144375359
-
CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice
-
Erdman, S. E. et al. CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice. Cancer Res. 65, 3998-4004 (2005).
-
(2005)
Cancer Res.
, vol.65
, pp. 3998-4004
-
-
Erdman, S.E.1
-
60
-
-
31544451792
-
Proinfl ammatory CD4+ CD45RB(hi) lymphocytes promote mammary and intestinal carcinogenesis in Apc (Min/+) mice
-
Rao, V. P. et al. Proinfl ammatory CD4+ CD45RB(hi) lymphocytes promote mammary and intestinal carcinogenesis in Apc (Min/+) mice. Cancer Res. 66, 57-61 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 57-61
-
-
Rao, V.P.1
-
61
-
-
0035879772
-
Bacterial infection promotes colon tumorigenesis in Apc (Min/+) mice
-
Newman, J. V., Kosaka, T., Sheppard, B. J., Fox, J. G. & Schauer, D. B. Bacterial infection promotes colon tumorigenesis in Apc (Min/+) mice. J. Infect. Dis. 184, 227-230 (2001).
-
(2001)
J. Infect. Dis.
, vol.184
, pp. 227-230
-
-
Newman, J.V.1
Kosaka, T.2
Sheppard, B.J.3
Fox, J.G.4
Schauer, D.B.5
-
62
-
-
69949120571
-
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17T cell responses
-
Wu, S. et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17T cell responses. Nat. Med. 15, 1016-1022 (2009).
-
(2009)
Nat. Med.
, vol.15
, pp. 1016-1022
-
-
Wu, S.1
-
63
-
-
77449142400
-
Unifying roles for regulatory T cells and infl ammation in cancer
-
Erdman, S. E. et al. Unifying roles for regulatory T cells and infl ammation in cancer. Int. J. Cancer 126, 1651-1665 (2010).
-
(2010)
Int. J. Cancer
, vol.126
, pp. 1651-1665
-
-
Erdman, S.E.1
-
64
-
-
33847041537
-
Breast cancer: Should gastrointestinal bacteria be on our radar screen?
-
Rao, V. P., Poutahidis, T., Fox, J. G. & Erdman, S. E. Breast cancer: Should gastrointestinal bacteria be on our radar screen? Cancer Res. 67, 847-850 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 847-850
-
-
Rao, V.P.1
Poutahidis, T.2
Fox, J.G.3
Erdman, S.E.4
-
65
-
-
0038610618
-
The complete genome sequence of the carcinogenic bacterium Helicobacter hepaticus
-
Suerbaum, S. et al. The complete genome sequence of the carcinogenic bacterium Helicobacter hepaticus. Proc. Natl Acad. Sci. USA 100, 7901-7906 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 7901-7906
-
-
Suerbaum, S.1
-
66
-
-
33845222309
-
The contribution of cytolethal distending toxin to bacterial pathogenesis
-
Smith, J. L. & Bayles, D. O. The contribution of cytolethal distending toxin to bacterial pathogenesis. Crit. Rev. Microbiol. 32, 227-248 (2006).
-
(2006)
Crit. Rev. Microbiol.
, vol.32
, pp. 227-248
-
-
Smith, J.L.1
Bayles, D.O.2
-
67
-
-
47549092184
-
In vivo virulence properties of bacterial cytolethal-distending toxin
-
Ge, Z., Schauer, D. B. & Fox, J. G. In vivo virulence properties of bacterial cytolethal-distending toxin. Cell Microbiol. 10, 1599-1607 (2008).
-
(2008)
Cell Microbiol.
, vol.10
, pp. 1599-1607
-
-
Ge, Z.1
Schauer, D.B.2
Fox, J.G.3
-
68
-
-
0034081113
-
Identifi cation of cdtB homologues and cytolethal distending toxin activity in enterohepatic Helicobacter spp
-
Chien, C. C. et al. Identifi cation of cdtB homologues and cytolethal distending toxin activity in enterohepatic Helicobacter spp. J. Med. Microbiol. 49, 525-534 (2000).
-
(2000)
J. Med. Microbiol.
, vol.49
, pp. 525-534
-
-
Chien, C.C.1
-
69
-
-
0347319588
-
Cytolethal distending toxin: A potential virulence factor for Helicobacter cinaedi
-
Taylor, N. S., Ge, Z., Shen, Z., Dewhirst, F. E. & Fox, J. G. Cytolethal distending toxin: A potential virulence factor for Helicobacter cinaedi. J. Infect. Dis. 188, 1892-1897 (2003).
-
(2003)
J. Infect. Dis.
, vol.188
, pp. 1892-1897
-
-
Taylor, N.S.1
Ge, Z.2
Shen, Z.3
Dewhirst, F.E.4
Fox, J.G.5
-
70
-
-
0033836386
-
Cytolethal distending toxin in avian and human isolates of Helicobacter pullorum
-
Young, V. B. et al. Cytolethal distending toxin in avian and human isolates of Helicobacter pullorum. J. Infect. Dis. 182, 620-623 (2000).
-
(2000)
J. Infect. Dis.
, vol.182
, pp. 620-623
-
-
Young, V.B.1
-
71
-
-
19744378055
-
Cytolethal distending toxin is essential for Helicobacter hepaticus colonization in outbred Swiss Webster mice
-
Ge, Z. et al. Cytolethal distending toxin is essential for Helicobacter hepaticus colonization in outbred Swiss Webster mice. Infect. Immun. 73, 3559-3567 (2005).
-
(2005)
Infect. Immun.
, vol.73
, pp. 3559-3567
-
-
Ge, Z.1
-
72
-
-
33746585280
-
Modulation of host immune responses by the cytolethal distending toxin of Helicobacter hepaticus
-
Pratt, J. S., Sachen, K. L., Wood, H. D., Eaton, K. A. & Young, V. B. Modulation of host immune responses by the cytolethal distending toxin of Helicobacter hepaticus. Infect. Immun. 74, 4496-4504 (2006).
-
(2006)
Infect. Immun.
, vol.74
, pp. 4496-4504
-
-
Pratt, J.S.1
Sachen, K.L.2
Wood, H.D.3
Eaton, K.A.4
Young, V.B.5
-
73
-
-
2142758715
-
In vitro and in vivo characterization of Helicobacter hepaticus cytolethal distending toxin mutants
-
Young, V. B. et al. In vitro and in vivo characterization of Helicobacter hepaticus cytolethal distending toxin mutants. Infect. Immun. 72, 2521-2527 (2004).
-
(2004)
Infect. Immun.
, vol.72
, pp. 2521-2527
-
-
Young, V.B.1
-
74
-
-
66549121984
-
Cytolethal distending toxin promotes Helicobacter cinaedi-associated typhlocolitis in interleukin-10-defi cient mice
-
Shen, Z. et al. Cytolethal distending toxin promotes Helicobacter cinaedi-associated typhlocolitis in interleukin-10-defi cient mice. Infect. Immun. 77, 2508-2516 (2009).
-
(2009)
Infect. Immun.
, vol.77
, pp. 2508-2516
-
-
Shen, Z.1
-
75
-
-
77749233744
-
Myc is required for activation of the ATM-dependent checkpoints in response to DNA damage
-
Guerra, L. et al. Myc is required for activation of the ATM-dependent checkpoints in response to DNA damage. PLoS One 5, e8924 (2010).
-
(2010)
PLoS One
, vol.5
-
-
Guerra, L.1
-
76
-
-
77749246230
-
Helicobacter hepaticus cytolethal distending toxin causes cell death in intestinal epithelial cells via mitochondrial apoptotic pathway
-
Liyanage, N. P. et al. Helicobacter hepaticus cytolethal distending toxin causes cell death in intestinal epithelial cells via mitochondrial apoptotic pathway. Helicobacter 15, 98-107 (2010).
-
(2010)
Helicobacter
, vol.15
, pp. 98-107
-
-
Liyanage, N.P.1
-
77
-
-
33749565756
-
Pathogenicity islands: A molecular toolbox for bacterial virulence
-
Gal-Mor, O. & Finlay, B. B. Pathogenicity islands: A molecular toolbox for bacterial virulence. Cell Microbiol. 8, 1707-1719 (2006).
-
(2006)
Cell Microbiol.
, vol.8
, pp. 1707-1719
-
-
Gal-Mor, O.1
Finlay, B.B.2
-
78
-
-
28444445594
-
Different Helicobacter hepaticus strains with variable genomic content induce various degrees of hepatitis
-
Boutin, S. R. et al. Different Helicobacter hepaticus strains with variable genomic content induce various degrees of hepatitis. Infect. Immun. 73, 8449-8452 (2005).
-
(2005)
Infect. Immun.
, vol.73
, pp. 8449-8452
-
-
Boutin, S.R.1
-
79
-
-
45849148064
-
Helicobacter hepaticus HHGI1 is a pathogenicity island associated with typhlocolitis in B6.129- IL10 tm1Cgn mice
-
Ge, Z. et al. Helicobacter hepaticus HHGI1 is a pathogenicity island associated with typhlocolitis in B6.129- IL10 tm1Cgn mice. Microbes. Infect. 10, 726-733 (2008).
-
(2008)
Microbes. Infect.
, vol.10
, pp. 726-733
-
-
Ge, Z.1
-
80
-
-
0034039960
-
Bacterial ureases in infectious diseases
-
Burne, R. A. & Chen, Y. Y. Bacterial ureases in infectious diseases. Microbes Infect. 2, 533-542 (2000).
-
(2000)
Microbes Infect.
, vol.2
, pp. 533-542
-
-
Burne, R.A.1
Chen, Y.Y.2
-
81
-
-
44649092624
-
Helicobacter hepaticus urease is not required for intestinal colonization but promotes hepatic infl ammation in male A/JCr mice
-
Ge, Z. et al. Helicobacter hepaticus urease is not required for intestinal colonization but promotes hepatic infl ammation in male A/JCr mice. Microb. Pathog. 45, 18-24 (2008).
-
(2008)
Microb. Pathog.
, vol.45
, pp. 18-24
-
-
Ge, Z.1
-
82
-
-
29244447384
-
Differential regulation of urease activity in Helicobacter hepaticus and Helicobacter pylori
-
Belzer, C. et al. Differential regulation of urease activity in Helicobacter hepaticus and Helicobacter pylori. Microbiology 151, 3989-3995 (2005).
-
(2005)
Microbiology
, vol.151
, pp. 3989-3995
-
-
Belzer, C.1
-
83
-
-
33846816947
-
Iron-responsive repression of urease expression in Helicobacter hepaticus is mediated by the transcriptional regulator Fur
-
Belzer, C., van Schendel, B. A., Kuipers, E. J., Kusters, J. G. & van Vliet, A. H. Iron-responsive repression of urease expression in Helicobacter hepaticus is mediated by the transcriptional regulator Fur. Infect. Immun. 75, 745-752 (2007).
-
(2007)
Infect. Immun.
, vol.75
, pp. 745-752
-
-
Belzer, C.1
Van Schendel, B.A.2
Kuipers, E.J.3
Kusters, J.G.4
Van Vliet, A.H.5
-
84
-
-
34247230489
-
Helicobacter hepaticus catalase shares surfacepredicted epitopes with mammalian catalases
-
Alyamani, E. J. et al. Helicobacter hepaticus catalase shares surfacepredicted epitopes with mammalian catalases. Microbiology 153, 1006-1016 (2007).
-
(2007)
Microbiology
, vol.153
, pp. 1006-1016
-
-
Alyamani, E.J.1
-
85
-
-
34247250292
-
A Helicobacter hepaticus catalase mutant is hypersensitive to oxidative stress and suffers increased DNA damage
-
Hong, Y., Wang, G. & Maier, R. J. A Helicobacter hepaticus catalase mutant is hypersensitive to oxidative stress and suffers increased DNA damage. J. Med. Microbiol. 56, 557-562 (2007).
-
(2007)
J. Med. Microbiol.
, vol.56
, pp. 557-562
-
-
Hong, Y.1
Wang, G.2
Maier, R.J.3
-
86
-
-
23944475683
-
Helicobacter hepaticus hydrogenase mutants are defi cient in hydrogen-supported amino acid uptake and in causing liver lesions in A/J mice
-
Mehta, N. S., Benoit, S., Mysore, J. V., Sousa, R. S. & Maier, R. J. Helicobacter hepaticus hydrogenase mutants are defi cient in hydrogen-supported amino acid uptake and in causing liver lesions in A/J mice. Infect. Immun. 73, 5311-5318 (2005).
-
(2005)
Infect. Immun.
, vol.73
, pp. 5311-5318
-
-
Mehta, N.S.1
Benoit, S.2
Mysore, J.V.3
Sousa, R.S.4
Maier, R.J.5
-
87
-
-
52649112717
-
Role of the Helicobacter hepaticus fl agellar sigma factor FliA in gene regulation and murine colonization
-
Sterzenbach, T. et al. Role of the Helicobacter hepaticus fl agellar sigma factor FliA in gene regulation and murine colonization. J. Bacteriol. 190, 6398-6408 (2008).
-
(2008)
J. Bacteriol.
, vol.190
, pp. 6398-6408
-
-
Sterzenbach, T.1
-
88
-
-
0034503471
-
Helicobacter hepaticus infection triggers infl ammatory bowel disease in T cell receptor alpha\beta mutant mice
-
Chin, E. Y., Dangler, C. A., Fox, J. G. & Schauer, D. B. Helicobacter hepaticus infection triggers infl ammatory bowel disease in T cell receptor alpha\beta mutant mice. Comp. Med. 50, 586-594 (2000).
-
(2000)
Comp. Med.
, vol.50
, pp. 586-594
-
-
Chin, E.Y.1
Dangler, C.A.2
Fox, J.G.3
Schauer, D.B.4
-
89
-
-
0030735193
-
Helicobacter bilis- Induced infl ammatory bowel disease in scid mice with defi ned fl ora
-
Shomer, N. H., Dangler, C. A., Schrenzel, M. D. & Fox, J. G. Helicobacter bilis- induced infl ammatory bowel disease in scid mice with defi ned fl ora. Infect. Immun. 65, 4858-4864 (1997).
-
(1997)
Infect. Immun.
, vol.65
, pp. 4858-4864
-
-
Shomer, N.H.1
Dangler, C.A.2
Schrenzel, M.D.3
Fox, J.G.4
-
90
-
-
0031772881
-
Helicobacter bilis / Helicobacter rodentium co-infection associated with diarrhea in a colony of scid mice
-
Shomer, N. H., Dangler, C. A., Marini, R. P. & Fox, J. G. Helicobacter bilis / Helicobacter rodentium co-infection associated with diarrhea in a colony of scid mice. Lab. Anim. Sci. 48, 455-459 (1998).
-
(1998)
Lab. Anim. Sci.
, vol.48
, pp. 455-459
-
-
Shomer, N.H.1
Dangler, C.A.2
Marini, R.P.3
Fox, J.G.4
-
91
-
-
0029781169
-
Persistent hepatitis and enterocolitis in germfree mice infected with Helicobacter hepaticus
-
Fox, J. G. et al. Persistent hepatitis and enterocolitis in germfree mice infected with Helicobacter hepaticus. Infect. Immun. 64, 3673-3681 (1996).
-
(1996)
Infect. Immun.
, vol.64
, pp. 3673-3681
-
-
Fox, J.G.1
-
92
-
-
0035260357
-
Typhlocolitis in NF-kappa B-defi cient mice
-
Erdman, S., Fox, J. G., Dangler, C. A., Feldman, D. & Horwitz, B. H. Typhlocolitis in NF-kappa B-defi cient mice. J. Immunol. 166, 1443-1447 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 1443-1447
-
-
Erdman, S.1
Fox, J.G.2
Dangler, C.A.3
Feldman, D.4
Horwitz, B.H.5
-
93
-
-
0036169116
-
Helicobacter bilis infection accelerates and H. hepaticus infection delays the development of colitis in multiple drug resistance-defi cient (mdr1a-/ -) mice
-
Maggio-Price, L. et al. Helicobacter bilis infection accelerates and H. hepaticus infection delays the development of colitis in multiple drug resistance-defi cient (mdr1a-/ -) mice. Am. J. Pathol. 160, 739-751 (2002).
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 739-751
-
-
Maggio-Price, L.1
-
94
-
-
31544465904
-
Helicobacter infection is required for infl ammation and colon cancer in SMAD3-defi cient mice
-
Maggio-Price, L. et al. Helicobacter infection is required for infl ammation and colon cancer in SMAD3-defi cient mice. Cancer Res. 66, 828-838 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 828-838
-
-
Maggio-Price, L.1
-
95
-
-
0033041980
-
A novel urease-negative Helicobacter species associated with colitis and typhlitis in IL-10-defi cient mice
-
Fox, J. G. et al. A novel urease-negative Helicobacter species associated with colitis and typhlitis in IL-10-defi cient mice. Infect. Immun. 67, 1757-1762 (1999).
-
(1999)
Infect. Immun.
, vol.67
, pp. 1757-1762
-
-
Fox, J.G.1
-
96
-
-
0034759480
-
Helicobacter typhlonius sp. nov., A novel murine urease-negative Helicobacter species
-
Franklin, C. L. et al. Helicobacter typhlonius sp. nov., a novel murine urease-negative Helicobacter species. J. Clin. Microbiol. 39, 3920-3926 (2001).
-
(2001)
J. Clin. Microbiol.
, vol.39
, pp. 3920-3926
-
-
Franklin, C.L.1
-
97
-
-
33845503040
-
Rapid onset of ulcerative typhlocolitis in B6. 129P2- IL10 tm1Cgn (IL-10-/ -) mice infected with Helicobacter trogontum is associated with decreased colonization by altered Schaedler β s fl ora
-
Whary, M. T. et al. Rapid onset of ulcerative typhlocolitis in B6. 129P2- IL10 tm1Cgn (IL-10-/ -) mice infected with Helicobacter trogontum is associated with decreased colonization by altered Schaedler β s fl ora. Infect. Immun. 74, 6615-6623 (2006).
-
(2006)
Infect. Immun.
, vol.74
, pp. 6615-6623
-
-
Whary, M.T.1
|