Helicobacter bilis infection accelerates and H. hepaticus infection delays the development of colitis in multiple drug resistance-deficient (mdr1a-/-) mice

American Journal of Pathology

Volumn 160, Issue 2, 2002, Pages 739-751

  Maggio Price, Lillian ^a,b   Shows, Donna ^b   Waggie, Kim ^c   Burich, Andrew ^a,b   Zeng, Weiping ^a   Escobar, Sabine ^b   Morrissey, Phil ^b   Viney, Joanne L ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b AMGEN INC   (United States)

^c Zymo Genetics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GLYCOPROTEIN P; INTERLEUKIN 10; PROTEIN MDR1A; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLITIS; CONTROLLED STUDY; CYTOKINE RELEASE; DIARRHEA; ENTERITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HELICOBACTER BILIS; HELICOBACTER HEPATICUS; HISTOPATHOLOGY; INFLAMMATORY CELL; INTESTINE CRYPT; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE SUBPOPULATION; WEIGHT REDUCTION;

EID: 0036169116     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64894-8     Document Type: Article

References (60)

1. Inflammatory bowel disease: Etiology and pathogenesis
2. CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice: Disease development is prevented by cotransfer of purified CD4+ T cells
3. Regulatory interactions between CD45RB high and CD45RB low CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity
4. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C.B-17 scid mice
5. Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses
6. Interleukin-10-deficient mice develop chronic enterocolitis
7. Increased nuclear factor-κB activation in colitis of interleukin-2-deficient mice
8. CD4+ T-cell population mediates development of inflammatory bowel disease in T-cell receptor α-chain-deficient mice
9. Gi2 α protein deficiency: A model of inflammatory bowel disease
10. Colitis in transgenic and knockout animals as models of human inflammatory bowel disease
11. The P-glycoprotein efflux pump: How does it transport drugs?
12. Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins
13. A novel model of inflammatory bowel disease: Mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis
14. Helicobacter: Species classification and identification
15. SCID/NCr mice naturally infected with Helicobacter hepaticus develop progressive hepatitis, proliferative typhlitis, and colitis
16. Persistent hepatitis and enterocolitis in germfree mice infected with Helicobacter hepaticus
17. Chronic proliferative hepatitis in A/JCr mice associated with persistent Helicobacter hepaticus infection: A model of helicobacter-induced carcinogenesis
18. Inflammatory large bowel disease in immunodeficient mice naturally infected with Helicobacter hepaticus
19. Enteric lesions in SCID mice infected with "Helicobacter typhlonicus," a novel urease-negative Helicobacter species
20. Helicobacter rodentium sp. nov., a urease-negative Helicobacter species isolated from laboratory mice
21. Helicobacter hepaticus triggers colitis in specificpathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12-and γ-interferon-dependent mechanism
22. Helicobacter bilis-induced inflammatory bowel disease in scid mice with defined flora
23. Enterohepatic lesions in SCID mice infected with Helicobacter bills
24. Inflammatory large bowel disease in immunodeficient rats naturally and experimentally infected with Helicobacter bilis
25. Inflammatory bowel disease: An immunity-mediated condition triggered by bacterial infection with Helicobacter hepaticus
26. Helicobacter-induced inflammatory bowel disease in IL-10- and T cell-deficient mice
27. Helicobacter hepaticus infection triggers inflammatory bowel disease in T cell receptor ab mutant mice
28. Identification of murine helicobacters by PCR and restriction enzyme analyses
29. Identification of widespread Helicobacter hepaticus infection in feces in commercial mouse colonies by culture and PCR assay
30. Helicobacter bills sp. nov., a novel Helicobacter species isolated from bile, livers, and intestines of aged, inbred mice
31. The "Swiss roll": A simple technique for histological studies of the rodent intestine
32. Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
33. A family of drug transporters: The multidrug resistance-associated proteins
34. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
35. Role of cytokines in the early stages of chronic colitis in TCR α-mutant mice
36. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice
37. Cytolethal distending toxin in avian and human isolates of Helicobacter pullorum
38. Identification of cdtB homologues and cytolethal distending toxin activity in enterohepatic Helicobacter spp
39. Cytolethal distending toxin sequence and activity in the enterohepatic pathogen Helicobacter hepaticus
40. Interferon-γ and interleukin-10 reciprocally regulate endothelial junction integrity and barrier function
41. CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: Increased T helper cell type 1 response and ability to transfer disease
42. Analyzing the molecular foundations of commensalism in the mouse intestine
43. Altered development of intestinal intraepithelial lymphocytes in P-glycoprotein-deficient mice
44. Spontaneously colitic C3H/HeJBir mice demonstrate selective antibody reactivity to antigens of the enteric bacterial flora
45. Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria
46. Citrobacter rodentium infection in mice elicits a mucosal Th1 cytokine response and lesions similar to those in murine inflammatory bowel disease
47. Chronic active hepatitis induced by Helicobacter hepaticus in the A/JCr mouse is associated with a Th1 cell-mediated immune response
48. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
49. Lessons from genetically engineered animal models. XII. IL-10-deficient (IL-10(-/-) mice and intestinal inflammation
50. Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12
51. Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease
52. Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease
53. Chronic colitis in IL-10-/- mice: Insufficient counter regulation of a Th1 response
54. Review article: Role of the enteric microflora in the pathogenesis of intestinal inflammation and arthritis
55. IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation
56. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
57. Colitis induced by enteric bacterial antigen-specific CD4+ T cells requires CD40-CD40 ligand interactions for a sustained increase in mucosal IL-12
58. Lactobacillus species prevents colitis in interleukin 10 gene-deficient mice
59. Differences in P-glycoprotein-170 expression and activity between Crohn's disease and ulcerative colitis
60. High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy