Nitric oxide and TNF-α trigger colonic inflammation and carcinogenesis in Helicobacter hepaticus-infected, Rag2-deficient mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 4, 2009, Pages 1027-1032

  Erdman, S E ^a   Rao, V P ^a   Poutahidis, T ^a,c   Rogers, A B ^a   Taylor, C L ^a   Jackson, E A ^a   Ge, Z ^a   Lee, C W ^a   Schauer, D B ^a,b   Wogan, G N ^b   Tannenbaum, S R ^b   Fox, J G ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Colorectal cancer; IBD; Innate immunity

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; N METHYL ARGININE; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; RAG2 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARCINOGENESIS; CD4 LYMPHOCYTE COUNT; COLITIS; COLON CANCER; CONTROLLED STUDY; DYSPLASIA; HELICOBACTER HEPATICUS; HELICOBACTER INFECTION; HYPERPLASIA; IMMUNOCOMPETENT CELL; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; URINARY EXCRETION;

ANIMALS; ARGININE; COLON; COLONIC NEOPLASMS; DNA-BINDING PROTEINS; ENZYME INHIBITORS; HELICOBACTER HEPATICUS; HELICOBACTER INFECTIONS; INFLAMMATION; INFLAMMATION MEDIATORS; MICE; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; TUMOR NECROSIS FACTOR-ALPHA;

HELICOBACTER HEPATICUS; MUS;

EID: 59049099999     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0812347106     Document Type: Article

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