Helicobacter hepaticus infection triggers inflammatory bowel disease in T cell receptor αβ mutant mice

Comparative Medicine

Volumn 50, Issue 6, 2000, Pages 586-594

  Chin, E Y ^a   Dangler, C A ^a   Fox, J G ^a   Schauer, D B ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; COLON CROHN DISEASE; CONTROLLED STUDY; EMBRYO TRANSFER; GRAM NEGATIVE INFECTION; HELICOBACTER HEPATICUS; MOUSE; MUTANT; NONHUMAN; PATHOGENESIS; ULCERATIVE COLITIS;

ANIMALS; CECUM; COLON; CROSSES, GENETIC; EMBRYO TRANSFER; FEMALE; GENES, T-CELL RECEPTOR ALPHA; GENES, T-CELL RECEPTOR BETA; HELICOBACTER; HELICOBACTER INFECTIONS; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA;

EID: 0034503471     PISSN: 00236764     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
2. Interleukin-10-deficient mice develop chronic enterocolitis
3. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice
4. Spontaneous inflammatory bowel disease in multiple mutant mouse lines: Association with colonization by Helicobacter hepaticus
5. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
6. T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment
7. Helicobacter hepaticus sp. nov., a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice
8. Helicobacter pylori
9. Helicobacter pylori
10. Identification of widespread Helicobacter hepaticus infection in feces in commercial mouse colonies by culture and PCR assay
11. Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species
12. Impact of Helicobacter hepaticus infection in B6C3F1 mice from twelve national toxicology program two-year carcinogenesis studies
13. SCID/NCr mice naturally infected with Helicobacter hepaticus develop progressive hepatitis, proliferative typhlitis, and colitis
14. Inflammatory large bowel disease in immunodeficient mice naturally infected with Helicobacter hepaticus
15. Inflammatory bowel disease: An immunity-mediated condition triggered by bacterial infection with Helicobacter hepaticus
16. IL-7 deficiency prevents development of a non-T cell non-B cell-mediated colitis
17. Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism
18. A novel urease-negative Helicobacter species associated with colitis and typhlitis in IL-10-deficient mice
19. Enteric lesions in SCID mice infected with "Helicobacter typhlonicus," a novel urease-negative Helicobacter species
20. Fecal PCR assay for diagnosis of Helicobacter infection in laboratory rodents
21. Helicobacter rodentium sp. nov., a urease-negative Helicobacter species isolated from laboratory mice
22. The expanding genus of Helicobacter: Pathogenic and zoonotic potential
23. Chronic active hepatitis induced by Helicobacter hepaticus in the A/JCr mouse is associated with a Th1 cell-mediated immune response
24. Differential susceptibility to hepatic inflammation and proliferation in AXB recombinant inbred mice chronically infected with Helicobacter hepaticus
25. Persistent hepatitis and enterocolitis in germfree mice infected with Helicobacter hepaticus
26. Biological markers of cell proliferation and differentiation in human gastrointestinal diseases
27. Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages
28. Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease
29. CD4+ T-cell population mediates development of inflammatory bowel disease in T-cell receptor alpha chain-deficient mice
30. Helicobacter bilis-induced inflammatory bowel disease in scid mice with defined flora
31. Enterohepatic lesions in SCID mice infected with Helicobacter bilis
32. Specific-pathogen-free conditions enhance inflammatory bowel disease in T-cell receptor knockout, but not C3H/HeJBir mice
33. Cryptosporidium parvum initiates inflammatory bowel disease in germfree T cell receptor-alpha-deficient mice
34. Lactobacillus species prevents colitis in interleukin 10 gene-deficient mice
35. In-vitro hepatotoxic factor in Helicobacter hepaticus, H. pylori and other Helicobacter species
36. Cytolethal distending toxin sequence and activity in the enterohepatic pathogen Helicobacter hepaticus
37. Essential role of urease in pathogenesis of gastritis induced by Helicobacter pylori in gnotobiotic piglets
38. Essential role of urease in vitro and in vivo Helicobacter pylori colonization study using a wild-type and isogenic urease mutant strain
39. Phylogeny of the defined murine microbiota: Altered Schaedler flora