Bacterial ureases in infectious diseases

Microbes and Infection

Volumn 2, Issue 5, 2000, Pages 533-542

  Burne, Robert A ^a   Chen, Yi Ywan M ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Ecology; Helicobacter; Oral microbes; Pathogenesis; Urinary tract

Indexed keywords

AMMONIA; BACTERIAL ENZYME; CARBON DIOXIDE; NICKEL; UREA; UREASE;

BACTERIAL GENE; BACTERIAL INFECTION; ENZYME MECHANISM; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; HELICOBACTER PYLORI; NONHUMAN; PERIODONTITIS; PRIORITY JOURNAL; PROVIDENCIA STUARTII; REVIEW; STREPTOCOCCUS; UREA CYCLE; URINARY TRACT INFECTION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; HELICOBACTER; HELICOBACTER PYLORI; NEGIBACTERIA; POSIBACTERIA; PROVIDENCIA STUARTII; STREPTOCOCCUS;

EID: 0034039960     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(00)00312-9     Document Type: Review

References (83)

1. The Merck Manual of Diagnosis and Therapy, Merck and Co., Inc., Rahway, NJ, 1956.
2. Golub L.M., Borden S.M., Kleinberg I. Urea content of gingival crevicular fluid and its relationship to periodontal disease in humans. J. Periodont. Res. 6:1971;243-251.
3. Visek W.J. Effects of urea hydrolysis on cell life-span and metabolism [Review]. Fed. Proc. 31:1972;1178-1193.
4. Mc Lean R.J.C., Nickel J.C., Cheng K.J., Costerton J.W. The ecology and pathogenicity of urease-producing bacteria in the urinary tract [Review], CRC. Crit. Rev. Microbiol. 16:1988;37-79.
5. Mobley H.L.T., Island M.D., Hausinger R.P. Molecular biology of microbial ureases [Review]. Microbiol. Rev. 59:1995;451-480.
6. Mobley H.L.T., Hausinger R.P. Microbial ureases: significance, regulation, and molecular characterization [Review]. Microbiol. Rev. 53:1989;85-108.
7. Collins C.M., D'Orazio S.E.F. Bacterial ureases: structure, regulation of expression and role in pathogenesis [Review]. Mol. Microbiol. 9:1993;907-913.
8. Riddles P.W., Whan V., Blakeley R.L., Zerner B. Cloning and sequencing of a jack bean urease encoding cDNA. Gene. 108:1991;265-267.
9. Labigne A., Cussac V., Courcoux P. Shuttle cloning and nucleotide sequences of Helicobacter pylori genes responsible for urease activity. J. Bacteriol. 173:1991;1920-1931.
10. Cussac V., Ferrero R.L., Labigne A. Expression of Helicobacter pylori urease genes in Escherichia coli grown under nitrogen-limiting conditions. J. Bacteriol. 174:1992;2466-2473.
11. Jabri E., Carr M.B., Hausinger R.P., Karplus P.A. The crystal structure of urease from Klebsiella aerogenes. Science. 268:1995;998-1004.
12. Lee M.H., Pankratz H.S., Wang S., Scott R.A., Finnegan M.G., Johnson M.K., Ippolito J.A., Christianson D.W., Hausinger R.P. Purification and characterization of Klebsiella aerogenes UreE protein: a nickel-binding protein that functions in urease metallocenter assembly. Prot. Sci. 2:1993;1042-1052.
13. Park I.S., Carr M.B., Hausinger R.P. In vitro activation of urease apoprotein and role of UreD as a chaperone required for nickel metallocenter assembly. Proc. Natl. Acad. Sci. USA. 91:1994;3233-3237.
14. Park I.S., Hausinger R.P. Requirement of carbon dioxide for in vitro assembly of the urease nickel metallocenter. Science. 267:1995;1156-1158.
15. Mobley H.L.T., Garner R.M., Bauerfeind P. Helicobacter pylori nickel-transport gene nixA: synthesis of catalytically active urease in Escherichia coli independent of growth conditions. Mol. Microbiol. 16:1995;97-109.
16. Maeda M., Hidaka M., Nakamura A., Masaki H., Uozumi T. Cloning, sequencing, and expression of thermophilic Bacillus sp. strain TB-90 urease gene complex in Escherichia coli. J. Bacteriol. 176:1994;432-442.
17. Chen Y.M., Clancy K.A., Burne R.A. Streptococcus salivarius urease: genetic and biochemical characterization and expression in a dental plaque streptococcus. Infect. Immun. 64:1996;585-592.
18. Chen Y.M., Weaver C.A., Mendelsohn D.R., Burne R.A. Transcriptional regulation of the Streptococcus salivarius 57. I urease operon. J. Bacteriol. 180:1998;5769-5775.
19. Sissons C.H., Hancock E.M., Perinpanayagam H.E.R., Cutress T.W. The bacteria responsible for ureolysis in artificial dental plaque. Arch. Oral Biol. 33:1988;727-734.
20. Gruter L., Endres M., Gatermann S. Cloning and expression of Staphylococcus epidermidis urease gene sequences in Staphylococcus carnosus. FEMS Microbiol. Lett. 72:1992;33-35.
21. D'Orazio S.E.F., Collins C.M. The plasmid-encoded urease gene cluster of the family Enterobacteriaceae is positively regulated by UreR, a member of the AraC family of transcriptional activators. J. Bacteriol. 175:1993;3459-3467.
22. Thomas V.J., Collins C.M. Identification of UreR binding sites in the Enterobacteriaceae plasmid-encoded and Proteus mirabilis urease gene operons. Mol. Microbiol. 31:1999;1417-1428.
23. Collins C.M., Gutman D.M., Laman H. Identification of a nitrogen-regulated promoter controlling expression of Klebsiella pneumoniae urease genes. Mol. Microbiol. 8:1993;187-198.
24. Schwacha A., Bender R.A. The product of the Klebsiella aerogenes nac (nitrogen assimilation control) gene is sufficient for activation of the hut operons and repression of the gdh operon. J. Bacteriol. 175:1993;2116-2124.
25. Sissons C.H., Perinpanayagam H.E.R., Hancock E.M., Cutress T.W. pH regulation of urease levels in Streptococcus salivarius. J. Dent. Res. 69:1990;1131-1137.
26. Sissons C.H., Hancock E.M. Urease activity in Streptococcus salivarius at low pH. Arch. Oral Biol. 38:1993;507-516.
27. Chen Y.M., Burne R.A. Analysis of Streptococcus salivarius urease expression using continuous chemostat culture. FEMS Microbiol. Lett. 135:1996;223-229.
28. Chen Y.M., Hall T.H., Burne R.A. Streptococcus salivarius urease expression: involvement of the phosphoenolpyruvate:sugar phosphotransferase system. FEMS Microbiol. Lett. 165:1998;117-122.
29. Rektorschek M., Weeks D., Sachs G., Melchers K. Influence of pH on metabolism and urease activity of Helicobacter pylori. Gastroenterology. 115:1998;628-641.
30. Courtemanch L., May C.A., Mobley H.L.T., Slonczewski J.L. Urease regulation in Proteus mirabilis: pH dependence and putative domains of UreR. Am. Soc. Microbiol. K41:1999.
31. Morou-Bermudez E., Burne R.A. Genetic and physiologic characterization of urease of Actinomyces naeslundii. Infect. Immun. 67:1999;504-512.
32. Sachs G., Meyer-Rosberg K., Scott D.R., Melchers K. Acid, protons and Helicobacter pylori [Review]. Yale J. Biol. M. 69:1996;301-316.
33. Scott D.R., Weeks D., Hong C., Postius S., Melchers K., Sachs G. The role of internal urease in acid resistance of Helicobacter pylori. Gastroenterology. 114:1998;58-70.
34. Smith D.G., Russell W.C., Ingledew W.J., Thirkell D. Hydrolysis of urea by Ureaplasma urealyticum generates a transmembrane potential with resultant ATP synthesis. J. Bacteriol. 175:1993;3253-3258.
35. Jahns T. Ammonium/urea-dependent generation of a proton electrochemical potential and synthesis of ATP in Bacillus pasteurii. J. Bacteriol. 178:1996;403-409.
36. Suzuki M., Miura S., Suematsu M., Fukumura D., Kurose I., Suzuki H., Kai A., Kudoh Y., Ohashi M., Tsuchiya M. Helicobacter pylori associated ammonia production enhances neutrophil-dependent gastric mucosal cell injury. Am. J. Physiol. 263:1992;G719-G725.
37. Goodwin C.S., Armstrong J.A., Marshall B.J. Campylobacter pyloridis, gastritis, and peptic ulceration [Review]. J. Clin. Pathol. 39:1986;353-365.
38. Suerbaum S., Josenhans C. Virulence factors of Helicobacter pylori: implications for vaccine development [Review]. Mol. Med. Today. 5:1999;32-39.
39. Mc Gee D.J., Mobley H.L.T. Mechanisms of Helicobacter pylori infection: bacterial factors [Review]. Curr. Top. Microbiol. Immunol. 241:1999;155-180.
40. Marshall B.J., Barrett L.J., Prakash C., Mc Callum R.W., Guerrant R.L. Urea protects Helicobacter (Campylobacter) pylori from the bactericidal effect of acid. Gastroenterology. 99:1990;697-702.
41. Karita M., Tsuda M., Nakazawa T. Essential role of urease in vitro and in vivo Helicobacter pylori colonization study using a wild-type and isogenic urease mutant strain. J. Clin. Gastroenterol. 21:1995;S160-S163.
42. Hawtin P.R., Stacey A.R., Newell D.G. Investigation of the structure and localization of the urease of Helicobacter pylori using monoclonal antibodies. J. Gen. Microbiol. 136:1990;1995-2000.
43. Phadnis S.H., Parlow M.H., Levy M., Ilver D., Caulkins C.M., Connors J.B., Dunn B.E. Surface localization of Helicobacter pylori urease and a heat shock protein homolog requires bacterial autolysis. Infect. Immun. 64:1996;905-912.
44. Chen G., Fournier R.L., Varanasi S., Mahama-Relue P.A. Helicobacter pylori survival in gastric mucosa by generation of a pH gradient. Biophys. J. 73:1997;1081-1088.
45. Krishnamurthy P., Parlow M., Zitzer J.B., Vakil N.B., Mobley H.L.T., Levy M., Phadnis S.H., Dunn B.E. Helicobacter pylori containing only cytoplasmic urease is susceptible to acid. Infect. Immun. 66:1998;5060-5066.
46. Smoot D.T., Mobley H.L.T., Chippendale G.R., Lewison J.F., Resau J.H. Helicobacter pylori urease activity is toxic to human gastric epithelial cells. Infect. Immun. 58:1990;1992-1994.
47. Suzuki H., Mori M., Suzuki M., Sakurai K., Miura S., Ishii H. Extensive DNA damage induced by monochloramine in gastric cells. Cancer Lett. 115:1997;243-248.
48. Futagami S., Takahashi H., Norose Y., Kobayashi M. Systemic and local immune responses against Helicobacter pylori urease in patients with chronic gastritis: distinct IgA and IgG productive sites. Gut. 43:1998;168-175.
49. Mohammadi M., Czinn S., Redline R., Nedrud J. Helicobacter-specific cell-mediated immune responses display a predominant Th1 phenotype and promote a delayed-type hypersensitivity response in the stomachs of mice. J. Immunol. 156:1996;4729-4738.
50. Mitchell H.M. The epidemiology of Helicobacter pylori [Review]. Curr. Top. Microbiol. Immunol. 241:1999;11-30.
51. Blanchard T.G., Czinn S.J., Nedrud J.G. Host response and vaccine development to Helicobacter pylori infection [Review]. Curr. Top. Microbiol. Immunol. 241:1999;181-213.
52. Chen M., Lee A., Hazell S.L., Hu P., Li Y. Lack of protection against gastric Helicobacter infection following immunization with jack bean urease: the rejection of a novel hypothesis. FEMS Microbiol. Lett. 116:1994;245-250.
53. Lee C.K., Weltzin R., Thomas W.D. Jr, et al. Oral immunization with recombinant Helicobacter pylori urease induces secretory IgA antibodies and protects mice from challenge with Helicobacter felis. J. Infect. Dis. 172:1995;161-172.
54. Dubois A., Lee C.K., Fiala N., Kleanthous H., Mehlman P.T., Monath T. Immunization against natural Helicobacter pylori infection in nonhuman primates. Infect. Immun. 66:1998;4340-4346.
55. Lee C.K., Soike K., Hill J., Georgakopoulos K., Tibbitts T., Ingrassia J., Gray H., Boden J., Kleanthous H., Giannasca P., Ermak T., Weltzin R., Blanchard J., Monath T.P. Immunization with recombinant Helicobacter pylori urease decreases colonization levels following experimental infection of rhesus monkeys. Vaccine. 17:1999;1493-1505.
56. Myers G.A., Ermak T.H., Georgakopoulos K., Tibbitts T., Ingrassia J., Gray H., Kleanthous H., Lee C.K., Monath T.P. Oral immunization with recombinant Helicobacter pylori urease confers long-lasting immunity against Helicobacter felis infection. Vaccine. 17:1999;1394-1403.
57. Michetti P., Kreiss C., Kotloff K.L., Porta N., Blanco J.L., Bachmann D., Herranz M., Saldinger P.F., Corthesy-Theulaz I., Losonsky G., Nichols R., Simon J., Stolte M., Ackerman S., Monath T.P., Blum A.L. Oral immunization with urease and Escherichia coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori-infected adults. Gastroenterology. 116:1999;804-812.
58. Griffith D.P., Musher D.M., Itin C. Urease. The primary cause of infection-induced urinary stones. Invest. Urol. 13:1976;346-350.
59. Maclaren D.M. The significance of urease in Proteus pyelonephritis: a bacteriological study. J. Pathol. Bacteriol. 96:1968;45-56.
60. Braude A.L., Siemienski J. Role of bacterial urease in experimental phylonephritis. J. Bacteriol. 80:1960;171-179.
61. Musher D.M., Griffith D.P., Yawn D., Rossen R.D. Role of urease in pyelonephritis resulting from urinary tract infection with Proteus. J. Infect. Dis. 131:1975;177-181.
62. Mobley H.L.T., Chippendale G.R., Swihart K.G., Welch R.A. Cytotoxicity of the HpmA hemolysin and urease of Proteus mirabilis and Proteus vulgaris against cultured human renal proximal tubular epithelial cells. Infect. Immun. 59:1991;2036-2042.
63. Jones B.D., Lockatell C.V., Johnson D.E., Warren J.W., Mobley H.L.T. Construction of a urease-negative mutant of Proteus mirabilis: analysis of virulence in a mouse model of ascending urinary tract infection. Infect. Immun. 58:1990;1120-1123.
64. Johnson D.E., Russell R.G., Lockatell C.V., Zulty J.C., Warren J.W., Mobley H.L.T. Contribution of Proteus mirabilis urease to persistence, urolithiasis, and acute pyelonephritis in a mouse model of ascending urinary tract infection. Infect. Immun. 61:1993;2748-2754.
65. Dumanski A.J., Hedelin H., Edin-Liljegren A., Beauchemin D., Mc Lean R.J. Unique ability of the Proteus mirabilis capsule to enhance mineral growth in infectious urinary calculi. Infect. Immun. 62:1994;2998-3003.
66. Gatermann S., John J., Marre R. Staphylococcus saprophyticus urease: characterization and contribution to uropathogenicity in unobstructed urinary tract infection of rats. Infect. Immun. 57:1989;110-116.
67. Gatermann S., Marre R. Cloning and expression of Staphylococcus saprophyticus urease gene sequences in Staphylococcus carnosus and contribution of the enzyme to virulence. Infect. Immun. 57:1989;2998-3002.
68. Monack D.M., Falkow S. Cloning of Bordetella bronchiseptica urease genes and analysis of colonization by a urease-negative mutant strain in a guinea-pig model. Mol. Microbiol. 10:1993;545-553.
69. Probst P., Hermann E., Meyer Zum Buschenfelde K.H., Fleischer B. Identification of the Yersinia enterocolitica urease β-subunit as a target antigen for human synovial T lymphocytes in reactive arthritis. Infect. Immun. 61:1993;4507-4509.
70. Singer D.L., Chatterjee R., Denepitiya L., Kleinberg I. A comparison of the acid-base metabolisms of pooled human dental plaque and salivary sediment. Arch. Oral Biol. 28:1983;29-35.
71. Biswas S.D., Kleinberg I. Effect of urea concentration on its utilization, on the pH and the formation of ammonia and carbon dioxide in a human salivary sediment system. Arch. Oral Biol. 16:1971;759-780.
72. Sissons C.H., Cutress T.W., Pearce E.I. Kinetics and product stoichiometry of ureolysis by human salivary bacteria and artificial mouth plaques. Arch. Oral Biol. 30:1985;781-790.
73. Salako N.O., Kleinberg I. Incidence of selected ureolytic bacteria in human dental plaque from sites with differing salivary access. Arch. Oral Biol. 34:1989;787-791.
74. Kleinberg I. Effect of urea concentrations on plaque pH in vivo. J. Dent. Res. 40:1961;751-752.
75. Wijeyeweera R.L., Kleinberg I. Acid-base pH curves in vitro with mixtures of pure cultures of human oral microorganisms. Arch. Oral Biol. 34:1989;55-64.
76. Peterson S., Woodhead J., Crall J. Caries resistance in children with chronic renal failure: plaque pH, salivary pH, and salivary composition. Pediatric Res. 19:1985;796-799.
77. Pearce E.I., Wakefield J.S., Sissons C.H. Therapeutic mineral enrichment of dental plaque visualized by transmission electron microscopy. J. Dent. Res. 70:1991;90-94.
78. Clancy K.A., Burne R.A. Construction and characterization of a recombinant ureolytic Streptococcus mutans and its use to demonstrate the relationship of urease activity to pH modulating capacity. FEMS Microbiol. Lett. 151:1997;205-211.
79. Clancy K.A., Burne R.A. Genetically-engineered implantable urease-producing Streptococcus mutans strains. J. Dent. Res. 77:1998;926.
80. Epstein S.R, Mandel I, Scopp I.W. Salivary composition and calculus formation in patients undergoing hemodialysis. J. Periodontol. 51:1980;336-338.
81. Mandel I.D., Thompson R.H. Jr. The chemistry of parotid and submaxillary saliva in heavy calculus formers and non-formers. J. Periodontol. 38:1967;310-315.
82. Biswas S., Duperon D.F., Chebib F.S. Study of periodontal disease in children and young adolescents. I. Effect of age, sex, gingival inflammation on crevice fluid volume, pocket depth, pH of supragingival plaque and crevice, collagenase activity and urea. J. Periodont. Res. 12:1977;250-264.
83. 4Cl on human gingival fibroblasts. Scand. J. Dent. Res. 93:1985;39-45.