Immunohistochemical localization and activity of glutathione transferase zeta (GSTZ1-1) in rat tissues

Drug Metabolism and Disposition

Volumn 30, Issue 6, 2002, Pages 616-625

  Lantum, Hoffman B M ^a   Baggs, Raymond B ^a   Krenitsky, Daria M ^a   Board, Philip G ^b   Anders, M W ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b Biology and Environment   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; ACETONE; ALPHA HALOACID DERIVATIVE; CARCINOGEN; CHLOROFLUOROACETIC ACID; DICHLOROACETIC ACID; DRINKING WATER; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE ZETA; HALOACID; MALEYLACETONE; TYROSINE; UNCLASSIFIED DRUG;

ADRENAL MEDULLA; AIRWAY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; BLADDER; BRAIN; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME LOCALIZATION; GASTROINTESTINAL TRACT; HEART; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; LIVER; MALE; MULTIPLE ORGAN FAILURE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; PROSTATE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN METABOLISM; RAT; TESTIS;

ACETIC ACIDS; ACETONE; ANIMALS; DICHLOROACETATE; ENVIRONMENTAL POLLUTANTS; GLUTATHIONE TRANSFERASE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MALEATES; ORGAN SPECIFICITY; RATS; RATS, INBRED F344; SUBCELLULAR FRACTIONS;

ANIMALIA; CANIS FAMILIARIS; RODENTIA;

EID: 0036265997     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.6.616     Document Type: Article

References (79)

1. Characterization and localization of glutathione-S-transferases in rat brain and binding of hormones, neurotransmitters, and drugs
2. 3 subunit is governed by tandem direct repeat octamer motifs in the 5′-flanking region of its gene
3. Inactivation of glutathione transferase zeta by dichloroacetic acid and other fluorine-lacking alpha-haloalkanoic acids
4. Immunocytochemical localization of glutathione S-transferases in human lung
5. Structure, catalytic mechanism, and evolution of the glutathione transferases
6. Ninety day toxicity study of chloroacetic acids in rats
7. Zeta, a novel class of glutathione transferases in a range of species from plants to humans
8. Water chlorination: Essential process or cancer hazard?
9. Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate
10. Immunohistologic localization of alpha, mu, and pi class glutathione S-transferases in human tissues
11. Glutathione S-transferase in human brain
12. Biochemical, pathologic and morphometric alterations induced in male B6C3F1 mouse liver by short-term exposure to dichloroacetic acid
13. Quantitative and qualitative gender-related differences in jejunal glutathione S-transferase in the rat effect of testosterone administration
14. 90-Day toxicity study of dichloroacetate in dogs
15. Inhibition of glutathione S-transferase zeta and tyrosine metabolism by dichloroacetate: A potential unifying mechanism for its altered biotransformation and toxicity
16. Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde, and dichloroacetic acid in the male B6C3F1 mouse
17. The carcinogenicity of dichloroacetic acid in the male Fischer 344 rat
18. The carcinogenicity of dichloroacetic acid in the male B6C3F1 mouse
19. Comparison of the distribution of microsomal and cytosolic glutathione S-transferase activities in different organs of the rat
20. Gene structure, chromosomal location, and expression pattern of maleylacetoacetate isomerase
21. Characterization of a fungal maleylacetoacetate isomerase gene and identification of its human homologue
22. The synthesis of model compounds for maleylacetoacetic acid: Maleylacetone
23. Differential expression of glutathione S-transferase isoforms in compartments of the testis and segments of the epididymis of the rat
24. Distribution of glutathione S-transferase isoenzymes in human kidney: Basis for possible markers of renal injury
25. Glutathione S-transferases in alcoholic liver disease
26. Developmental and hormonal regulation of the major form of hepatic glutathione S-transferase in male mice
27. Use of immuno-blot techniques to discriminate between the glutathione S-transferase Yf, Yk, Ya, Yn/Yb and Yc subunits and to study their distribution in extrahepatic tissues
28. Kinetics and metabolism of chloral hydrate in children: Identification of dichloroacetate as a metabolite
29. Novel theta class glutathione S-transferases Yrs-Yrs′ and Yrs′-Yrs′ in rat liver cytosol: Their potent activity toward 5-sulfoxymethylchrysene, a reactive metabolite of the carcinogen 5-hydroxymethylchrysene
30. Comparative effects of haloacetic acids in whole embryo culture
31. Human mu-class glutathione S-transferases present in liver, skeletal muscle and testicular tissue
32. Human glutathione transferase A3-3, a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones
33. Glutathione S-transferase isoenzymes in rat brain neurons and glia
34. Tissue distribution of enzymic methylation of glutathione S-transferase and its effects on catalytic activity. Methylation of glutathione S-transferase II-11 inhibits conjugating activity towards 1-chloro-2,4-dinitrobenzene
35. Purification, characterization and tissue distribution of human class theta glutathione S-transferase T1-1
36. Dichloroacetate, sodium: 3-Month oral toxicity studies in rats and dogs
37. The properties of maleylacetoacetate, the initial product of homogentisate oxidation in liver
38. Maleylacetoacetate isomerase
39. Tissue distribution, excretion, and urinary metabolites of dichloroacetic acid in the male Fischer 344 rat
40. Spermatotoxicity of dichloroacetic acid
41. Spermatotoxicity of dibromoacetic acid in rats after 14 daily exposures
42. Effects of dichloroacetate (DCA) on serum insulin levels and insulin-controlled signaling proteins in livers of male B6C3F1 mice
43. Dichloroacetic acid: Metabolism in cytosol
44. Human testicular glutathione S-transferases: Insights into tissue-specific expression of the diverse subunit classes
45. Human glutathione transferases: Classification, tissue distribution, structure, and functional properties
46. Subchronic 90 day toxicity of dichloroacetic and trichloroacetic acid in rats
47. The extent of dichloroacetate formation from trichloroethylene, chloral hydrate, trichloroacetate, and trichloroethanol in B6C3F1 mice
48. Theta, a new class of glutathione transferases purified from rat and man
49. Hypertyrosinemia
50. The distribution of microsomal glutathione transferase among different organelles, different organs, and different organisms
51. Behavioral evaluation of the neurotoxicity produced by dichloroacetic acid in rats
52. Increased expression of c-myc and c-H-ras in dichloroacetate and trichloroacetate-induced liver tumors in B6C3F1 mice
53. The structure of the rat glutathione S-transferase P gene and related pseudogenes
54. Immunolocalization of microsomal glutathione S-transferase in rat tissues
55. Mercapturic acid formation: The several glutathione transferases of rat liver
56. Carcinogenic activity of dichloroacetic acid and trichloroacetic acid in the liver of female B6C3F1 mice
57. Immunohistochemical localization of glutathione S-transferases in livers of untreated rats
58. Immumohistochemical analysis of dichloroacetic acid (DCA)-induced hepatocarcinogenesis in male Fischer (F344) rats
59. Subunit diversity and tissue distribution of human glutathione S-transferases: Interpretations based on electrospray ionization-MS and peptide sequence-specific antisera
60. Rationale for reclassification of a distinctive subdivision of mammalian class mu glutathione S-transferases that are primarily expressed in testis
61. Glutathione transferases of classes α, μ and π show selective expression in different regions of rat kidney
62. Glutathione S-transferases - A review
63. Evidence that human class theta glutathione S-transferase T1-1 can catalyse the activation of dichloromethane, a liver and lung carcinogen in the mouse. Comparison of the tissue distribution of GST T1-1 with that of classes alpha, mu and pi GST in human
64. Developmental toxicity of dichloroacetate in the rat
65. Treatment of lactic acidosis with dichloroacetate
66. Chronic toxicity of dichloroacetate: Possible relation to thiamine deficiency in rats
67. Pharmacokinetics, metabolism, and toxicology of dichloroacetate
68. Glutathione transferases in the urine: Sensitive methods for detection of kidney damage induced by nephrotoxic agents in humans
69. Urinary π-class glutathione transferase as an indicator of tubular damage in the human kidney
70. Immunohistochemical localization of α and π class glutathione transferases in normal human tissues
71. An immunohistochemical study of Pi class glutathione S-transferase expression in normal human tissue
72. Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid
73. Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other α-haloacids
74. Adverse male reproductive effects following subchronic exposure of rats to sodium dichloroacetate
75. Tissue-specific expression of the rat glutathione S-transferases
76. Polymorphism- and species-dependent inactivation of glutathione transferase zeta by dichloroacetate
77. Chlorinated acids and chloral in drinking water
78. Exposure estimates to disinfection by-products of chlorinated drinking water
79. Immunohistochemistry of omega class glutathione S-transferase in human tissues