Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury

FASEB Journal

Volumn 20, Issue 14, 2006, Pages

  Leonard, Martin O ^a   Kieran, Niamh E ^a   Howell, Katherine ^a   Burne, Melissa J ^c   Varadarajan, Raghu ^b   Dhakshinamoorthy, Saravanakumar ^d   Porter, Alan G ^d   O'Farrelly, Cliona ^b   Rabb, Hamid ^c   Taylor, Cormac T ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^c JOHNS HOPKINS HOSPITAL   (United States)

^d INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

Antioxidant response element; Hypoxia; Ischemic preconditioning; NQO1

Indexed keywords

ALDEHYDE DEHYDROGENASE; GLUTATHIONE TRANSFERASE; NADPH QUINONE OXIDOREDUCTASE; OXIDOREDUCTASE; TRANSCRIPTION FACTOR NRF2; NFE2L2 PROTEIN, HUMAN; NFE2L2 PROTEIN, MOUSE; NQO1 PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ARTICLE; DNA SYNTHESIS; GENE EXPRESSION; HUMAN; HUMAN CELL; ISCHEMIA; MICROARRAY ANALYSIS; PRIORITY JOURNAL; REOXYGENATION; REPERFUSION INJURY; RNA ANALYSIS; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; KIDNEY DISEASE; LIVER; LIVER TRANSPLANTATION; METABOLISM; MOUSE; PROMOTER REGION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; GENE EXPRESSION REGULATION; HUMANS; KIDNEY DISEASES; LIVER; LIVER TRANSPLANTATION; MICE; NADPH DEHYDROGENASE; NF-E2-RELATED FACTOR 2; PROMOTER REGIONS (GENETICS); REPERFUSION INJURY; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 33845646748     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.05-5097fje     Document Type: Article

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