Inhibition of monoamine oxidase by selected C5- and C6-substituted isatin analogues

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 1, 2011, Pages 261-274

  Manley King, Clarina I ^a   Bergh, Jacobus J ^a   Petzer, Jacobus P ^a  

^a NORTH WEST UNIVERSITY   (South Africa)

Author keywords

Competitive inhibition; Isatin; Molecular docking; Monoamine oxidase; Reversible inhibition; Selectivity

Indexed keywords

5 (2 PHENYLETHYL)ISATIN; 5 (4 CHLOROPHENOXY)ISATIN; 5 (4 PHENYLBUTYL)ISATIN; 5 BENZYLOXYISATIN; 5 PHENOXYISATIN; 5 PHENYLISATIN; 5 STYRYLISATIN; 6 (2 PHENYLETHYL)ISATIN; 6 BENZYLOXYISATIN; 6 PHENOXYISATIN; 6 PHENYLISATIN; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; ISATIN DERIVATIVE; MONOAMINE OXIDASE B INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG SYNTHESIS; HUMAN; MOLECULAR DOCKING; STRUCTURE ACTIVITY RELATION;

CRYSTALLOGRAPHY, X-RAY; ISATIN; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MONOAMINE OXIDASE INHIBITORS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78650729131     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.11.028     Document Type: Article

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