Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 8, 2009, Pages 3104-3110

  Manley King, Clarina I ^a   Terre'Blanche, Gisella ^a   Castagnoli Jr , Neal ^b   Bergh, Jacobus J ^a   Petzer, Jacobus P ^a  

^a NORTH WEST UNIVERSITY   (South Africa)

^b EDWARD VIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

Author keywords

Competitive inhibition; Hydrolysis; Maleimide; Monoamine oxidase B; Reversible inhibitors

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; MALEIMIDE DERIVATIVE; MONOAMINE OXIDASE B INHIBITOR; N METHYL 2 (3 BROMOPHENYL)MALEIMIDE; N METHYL 2 (3 CHLOROPHENYL)MALEIMIDE; N METHYL 2 (3 FLUOROPHENYL)MALEIMIDE; N METHYL 2 (3 METHYLPHENYL)MALEIMIDE; N METHYL 2 (3 TRIFLUOROMETHYL)MALEIMIDE; N METHYL 2 PHENYLMALEIMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; HYDROGEN BOND; HYDROLYSIS;

ANIMALS; BINDING SITES; CATALYSIS; ENZYME INHIBITORS; HUMANS; KINETICS; MITOCHONDRIA, LIVER; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; PAPIO; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 64049100013     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.03.005     Document Type: Article

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