-
1
-
-
29444439348
-
Molecular aspects of regulation of collagen gene expression in fibrosis
-
Bhogal RK, Stoica CM, McGaha TL, Bona CA: Molecular aspects of regulation of collagen gene expression in fibrosis. J Clin Immunol (2005) 25(6):592-603.
-
(2005)
J Clin Immunol
, vol.25
, Issue.6
, pp. 592-603
-
-
Bhogal, R.K.1
Stoica, C.M.2
McGaha, T.L.3
Bona, C.A.4
-
2
-
-
0026446005
-
Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin 4
-
Postlethwaite AE, Holness MA, Katai H, Raghow R: Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin 4. J Clin Invest (1992) 90(4):1479-1485.
-
(1992)
J Clin Invest
, vol.90
, Issue.4
, pp. 1479-1485
-
-
Postlethwaite, A.E.1
Holness, M.A.2
Katai, H.3
Raghow, R.4
-
3
-
-
38549159026
-
Cellular and molecular mechanisms of fibrosis
-
Wynn TA: Cellular and molecular mechanisms of fibrosis. J Pathol (2008) 214(2):199-210.
-
(2008)
J Pathol
, vol.214
, Issue.2
, pp. 199-210
-
-
Wynn, T.A.1
-
4
-
-
0042889170
-
γ Interferon as an antifibrosis agent in skeletal muscle
-
Foster W, Li Y, Usas A, Somogyi G, Huard J: γ Interferon as an antifibrosis agent in skeletal muscle. J Orthop Res (2003) 21(5):798-804.
-
(2003)
J Orthop Res
, vol.21
, Issue.5
, pp. 798-804
-
-
Foster, W.1
Li, Y.2
Usas, A.3
Somogyi, G.4
Huard, J.5
-
5
-
-
77952313777
-
Differentiation of effector CD4 T cell populations (*)
-
Zhu J, Yamane H, Paul WE: Differentiation of effector CD4 T cell populations (*). Annu Rev Immunol (2010) 28:445-489.
-
(2010)
Annu Rev Immunol
, vol.28
, pp. 445-489
-
-
Zhu, J.1
Yamane, H.2
Paul, W.E.3
-
7
-
-
52649167708
-
CD4 T cells: Fates, functions, and faults
-
Zhu J, Paul WE: CD4 T cells: Fates, functions, and faults. Blood (2008) 112(5):1557-1569.
-
(2008)
Blood
, vol.112
, Issue.5
, pp. 1557-1569
-
-
Zhu, J.1
Paul, W.E.2
-
8
-
-
35548994594
-
Recent advancement of understanding pathogenesis of type 1 diabetes and potential relevance to diabetic nephropathy
-
Ichinose K, Kawasaki E, Eguchi K: Recent advancement of understanding pathogenesis of type 1 diabetes and potential relevance to diabetic nephropathy. Am J Nephrol (2007) 27(6):554-564.
-
(2007)
Am J Nephrol
, vol.27
, Issue.6
, pp. 554-564
-
-
Ichinose, K.1
Kawasaki, E.2
Eguchi, K.3
-
9
-
-
26244435934
-
Th1 cytokines in the pathogenesis of lupus nephritis: The role of IL-18
-
Calvani N, Tucci M, Richards HB, Tartaglia P, Silvestris F: Th1 cytokines in the pathogenesis of lupus nephritis: The role of IL-18. Autoimmun Rev (2005) 4(8):542-548.
-
(2005)
Autoimmun Rev
, vol.4
, Issue.8
, pp. 542-548
-
-
Calvani, N.1
Tucci, M.2
Richards, H.B.3
Tartaglia, P.4
Silvestris, F.5
-
10
-
-
77949655330
-
Th17 cytokines and arthritis
-
Lubberts E: Th17 cytokines and arthritis. Semin Immunopathol (2010) 32(1):43-53.
-
(2010)
Semin Immunopathol
, vol.32
, Issue.1
, pp. 43-53
-
-
Lubberts, E.1
-
12
-
-
77949656747
-
Th17 cells in autoimmune demyelinating disease
-
Segal BM: Th17 cells in autoimmune demyelinating disease. Semin Immunopathol (2010) 32(1):71-77.
-
(2010)
Semin Immunopathol
, vol.32
, Issue.1
, pp. 71-77
-
-
Segal, B.M.1
-
13
-
-
77949897036
-
Importance of cytokines in murine allergic airway disease and human asthma
-
Finkelman FD, Hogan SP, Hershey GK, Rothenberg ME, Wills-Karp M: Importance of cytokines in murine allergic airway disease and human asthma. J Immunol (2010) 184(4): 1663-1674.
-
(2010)
J Immunol
, vol.184
, Issue.4
, pp. 1663-1674
-
-
Finkelman, F.D.1
Hogan, S.P.2
Hershey, G.K.3
Rothenberg, M.E.4
Wills-Karp, M.5
-
14
-
-
77949875754
-
What determines Th2 differentiation, in vitro and?
-
Paul WE: What determines Th2 differentiation, in vitro and ? Immunol Cell Biol (2010) 88(3):236-239.
-
(2010)
Immunol Cell Biol
, vol.88
, Issue.3
, pp. 236-239
-
-
Paul, W.E.1
-
15
-
-
77949876116
-
Transcriptional regulation of Th2 cell differentiation
-
Zhu J: Transcriptional regulation of Th2 cell differentiation. Immunol Cell Biol (2010) 88(3):244-249.
-
(2010)
Immunol Cell Biol
, vol.88
, Issue.3
, pp. 244-249
-
-
Zhu, J.1
-
16
-
-
31144460961
-
GATA-3 promotes Th2 responses through three different mechanisms: Induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors
-
Zhu J, Yamane H, Cote-Sierra J, Guo L, Paul WE: GATA-3 promotes Th2 responses through three different mechanisms: Induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors. Cell Res (2006) 16(1):3-10.
-
(2006)
Cell Res
, vol.16
, Issue.1
, pp. 3-10
-
-
Zhu, J.1
Yamane, H.2
Cote-Sierra, J.3
Guo, L.4
Paul, W.E.5
-
17
-
-
0037342749
-
GATA-3 suppresses Th1 development by downregulation of STAT4 and not through effects on IL-12Rβ2 chain or T-bet
-
Usui T, Nishikomori R, Kitani A, Strober W: GATA-3 suppresses Th1 development by downregulation of STAT4 and not through effects on IL-12Rβ2 chain or T-bet. Immunity (2003) 18(3):415-428.
-
(2003)
Immunity
, vol.18
, Issue.3
, pp. 415-428
-
-
Usui, T.1
Nishikomori, R.2
Kitani, A.3
Strober, W.4
-
18
-
-
0028858399
-
Activation of the interleukin-5 promoter by cAMP in murine EL-4 cells requires the GATA-3 and CLE0 elements
-
Siegel MD, Zhang DH, Ray P, Ray A: Activation of the interleukin-5 promoter by cAMP in murine EL-4 cells requires the GATA-3 and CLE0 elements. J Biol Chem (1995) 270(41): 24548-24555.
-
(1995)
J Biol Chem
, vol.270
, Issue.41
, pp. 24548-24555
-
-
Siegel, M.D.1
Zhang, D.H.2
Ray, P.3
Ray, A.4
-
19
-
-
0036830465
-
Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus
-
Yamashita M, Ukai-Tadenuma M, Kimura M, Omori M, Inami M, Taniguchi M, Nakayama T: Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus. J Biol Chem (2002) 277(44): 42399-42408.
-
(2002)
J Biol Chem
, vol.277
, Issue.44
, pp. 42399-42408
-
-
Yamashita, M.1
Ukai-Tadenuma, M.2
Kimura, M.3
Omori, M.4
Inami, M.5
Taniguchi, M.6
Nakayama, T.7
-
20
-
-
0033667895
-
Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo
-
Agarwal S, Avni O, Rao A: Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo. Immunity (2000) 12(6):643-652.
-
(2000)
Immunity
, vol.12
, Issue.6
, pp. 643-652
-
-
Agarwal, S.1
Avni, O.2
Rao, A.3
-
21
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH: A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell (2000) 100(6):655-669.
-
(2000)
Cell
, vol.100
, Issue.6
, pp. 655-669
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, C.G.5
Glimcher, L.H.6
-
22
-
-
0035827347
-
Role of T-bet in commitment of Th1 cells before IL-12-dependent selection
-
Mullen AC, High FA, Hutchins AS, Lee HW, Villarino AV, Livingston DM, Kung AL, Cereb N, Yao TP, Yang SY, Reiner SL: Role of T-bet in commitment of Th1 cells before IL-12-dependent selection. Science (2001) 292(5523):1907-1910.
-
(2001)
Science
, vol.292
, Issue.5523
, pp. 1907-1910
-
-
Mullen, A.C.1
High, F.A.2
Hutchins, A.S.3
Lee, H.W.4
Villarino, A.V.5
Livingston, D.M.6
Kung, A.L.7
Cereb, N.8
Yao, T.P.9
Yang, S.Y.10
Reiner, S.L.11
-
23
-
-
33645065358
-
T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription
-
Usui T, Preiss JC, Kanno Y, Yao ZJ, Bream JH, O'Shea JJ, Strober W: T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription. J Exp Med (2006) 203(3):755-766.
-
(2006)
J Exp Med
, vol.203
, Issue.3
, pp. 755-766
-
-
Usui, T.1
Preiss, J.C.2
Kanno, Y.3
Yao, Z.J.4
Bream, J.H.5
O'Shea, J.J.6
Strober, W.7
-
24
-
-
0029937270
-
Impaired IL-12 responses and enhanced development of Th2 cells in STAT4-deficient mice
-
Kaplan MH, Sun YL, Hoey T, Grusby MJ: Impaired IL-12 responses and enhanced development of Th2 cells in STAT4-deficient mice. Nature (1996) 382(6587):174-177.
-
(1996)
Nature
, vol.382
, Issue.6587
, pp. 174-177
-
-
Kaplan, M.H.1
Sun, Y.L.2
Hoey, T.3
Grusby, M.J.4
-
25
-
-
15844396183
-
Requirement for STAT4 in interleukin-12-mediated responses of natural killer and T cells
-
Thierfelder WE, van Deursen JM, Yamamoto K, Tripp RA, Sarawar SR, Carson RT, Sangster MY, Vignali DA, Doherty PC, Grosveld GC, Ihle JN: Requirement for STAT4 in interleukin-12-mediated responses of natural killer and T cells. Nature (1996) 382(6587):171-174.
-
(1996)
Nature
, vol.382
, Issue.6587
, pp. 171-174
-
-
Thierfelder, W.E.1
Van Deursen, J.M.2
Yamamoto, K.3
Tripp, R.A.4
Sarawar, S.R.5
Carson, R.T.6
Sangster, M.Y.7
Vignali, D.A.8
Doherty, P.C.9
Grosveld, G.C.10
Ihle, J.N.11
-
26
-
-
18144438839
-
STAT4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation
-
Frucht DM, Aringer M, Galon J, Danning C, Brown M, Fan S, Centola M, Wu CY, Yamada N, El Gabalawy H, O'Shea JJ: STAT4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation. J Immunol (2000) 164(9):4659-4664.
-
(2000)
J Immunol
, vol.164
, Issue.9
, pp. 4659-4664
-
-
Frucht, D.M.1
Aringer, M.2
Galon, J.3
Danning, C.4
Brown, M.5
Fan, S.6
Centola, M.7
Wu, C.Y.8
Yamada, N.9
El Gabalawy, H.10
O'Shea, J.J.11
-
27
-
-
55349117409
-
Stat4 is required for T-bet to promote IL-12- dependent Th1 fate determination
-
Thieu VT, Qing Yu Q, Chang HC, Yeh N, Nguyen ET, Sehra S, Kaplan MH: Stat4 is required for T-bet to promote IL-12- dependent Th1 fate determination. Immunity (2008) 29(5): 679-690.
-
(2008)
Immunity
, vol.29
, Issue.5
, pp. 679-690
-
-
Thieu, V.T.1
Qing Yu, Q.2
Chang, H.C.3
Yeh, N.4
Nguyen, E.T.5
Sehra, S.6
Kaplan, M.H.7
-
28
-
-
0035997908
-
T-bet is a STAT1-induced regulator of IL-12R expression in nave CD4+ T cells
-
Afkarian M, Sedy JR, Yang J, Jacobson NG, Cereb N, Yang SY, Murphy TL, Murphy KM: T-bet is a STAT1-induced regulator of IL-12R expression in nave CD4+ T cells. Nat Immunol (2002) 3(6):549-557.
-
(2002)
Nat Immunol
, vol.3
, Issue.6
, pp. 549-557
-
-
Afkarian, M.1
Sedy, J.R.2
Yang, J.3
Jacobson, N.G.4
Cereb, N.5
Yang, S.Y.6
Murphy, T.L.7
Murphy, K.M.8
-
29
-
-
0344064893
-
STAT5 activation plays a critical role in Th2 differentiation
-
Zhu J, Cote-Sierra J, Guo L, Paul WE: STAT5 activation plays a critical role in Th2 differentiation. Immunity (2003) 19(5): 739-748.
-
(2003)
Immunity
, vol.19
, Issue.5
, pp. 739-748
-
-
Zhu, J.1
Cote-Sierra, J.2
Guo, L.3
Paul, W.E.4
-
30
-
-
0029876629
-
STAT6 is required for mediating responses to IL-4 and for development of Th2 cells
-
Kaplan MH, Schindler U, Smiley ST, Grusby MJ: STAT6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity (1996) 4(3):313-319.
-
(1996)
Immunity
, vol.4
, Issue.3
, pp. 313-319
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
32
-
-
75749097320
-
Th1 and Th17 cells: Adversaries and collaborators
-
Damsker JM, Hansen AM, Caspi RR: Th1 and Th17 cells: Adversaries and collaborators. Ann NY Acad Sci (2010) 1183: 211-221.
-
(2010)
Ann NY Acad Sci
, vol.1183
, pp. 211-221
-
-
Damsker, J.M.1
Hansen, A.M.2
Caspi, R.R.3
-
33
-
-
2442484053
-
Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi S: Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol (2004) 22:531-562.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
34
-
-
65549136983
-
Mechanisms of Foxp3+ T regulatory cellmediated suppression
-
Shevach EM: Mechanisms of Foxp3+ T regulatory cellmediated suppression. Immunity (2009) 30(5):636-645.
-
(2009)
Immunity
, vol.30
, Issue.5
, pp. 636-645
-
-
Shevach, E.M.1
-
35
-
-
33847667225
-
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
-
Afzali B, Lombardi G, Lechler RI, Lord GM: The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol (2007) 148(1):32-46.
-
(2007)
Clin Exp Immunol
, vol.148
, Issue.1
, pp. 32-46
-
-
Afzali, B.1
Lombardi, G.2
Lechler, R.I.3
Lord, G.M.4
-
36
-
-
77951717543
-
Role of Treg in immune regulation of allergic diseases
-
Palomares O, Yaman G, Azkur AK, Akkoc T, Akdis M, Akdis CA: Role of Treg in immune regulation of allergic diseases. Eur J Immunol (2010) 40(5):1232-1240.
-
(2010)
Eur J Immunol
, vol.40
, Issue.5
, pp. 1232-1240
-
-
Palomares, O.1
Yaman, G.2
Azkur, A.K.3
Akkoc, T.4
Akdis, M.5
Akdis, C.A.6
-
37
-
-
56349093347
-
IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3- effector T cells
-
Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho IC, Khoury S et al: IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3- effector T cells. Nat Immunol (2008) 9(12):1347-1355.
-
(2008)
Nat Immunol
, vol.9
, Issue.12
, pp. 1347-1355
-
-
Dardalhon, V.1
Awasthi, A.2
Kwon, H.3
Galileos, G.4
Gao, W.5
Sobel, R.A.6
Mitsdoerffer, M.7
Strom, T.B.8
Elyaman, W.9
Ho, I.C.10
Khoury, S.11
-
38
-
-
56349154943
-
Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
-
Veldhoen M, Uyttenhove C, van Snick J, Helmby H, Westendorf A, Buer J, Martin B, Wilhelm C, Stockinger B: Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol (2008) 9(12):1341-1346.
-
(2008)
Nat Immunol
, vol.9
, Issue.12
, pp. 1341-1346
-
-
Veldhoen, M.1
Uyttenhove, C.2
Van Snick, J.3
Helmby, H.4
Westendorf, A.5
Buer, J.6
Martin, B.7
Wilhelm, C.8
Stockinger, B.9
-
39
-
-
77955658181
-
Regulation of human Th9 differentiation by type i interferons and IL-21
-
Wong MT, Ye JJ, Alonso MN, Landrigan A, Cheung RK, Engleman E, Utz PJ: Regulation of human Th9 differentiation by type I interferons and IL-21. Immunol Cell Biol (2010) 88(6):624-631.
-
(2010)
Immunol Cell Biol
, vol.88
, Issue.6
, pp. 624-631
-
-
Wong, M.T.1
Ye, J.J.2
Alonso, M.N.3
Landrigan, A.4
Cheung, R.K.5
Engleman, E.6
Utz, P.J.7
-
41
-
-
55149113944
-
Welcome to the neighborhood: Epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites
-
Saenz SA, Taylor BC, Artis D: Welcome to the neighborhood: Epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev (2008) 226:172-190.
-
(2008)
Immunol Rev
, vol.226
, pp. 172-190
-
-
Saenz, S.A.1
Taylor, B.C.2
Artis, D.3
-
42
-
-
70049100374
-
Innate cells and T helper 2 cell immunity in airway inflammation
-
Barrett NA, Austen KF: Innate cells and T helper 2 cell immunity in airway inflammation. Immunity (2009) 31(3): 425-437.
-
(2009)
Immunity
, vol.31
, Issue.3
, pp. 425-437
-
-
Barrett, N.A.1
Austen, K.F.2
-
43
-
-
34447281733
-
Interleukin 25 promotes the initiation of proallergic type 2 responses
-
Angkasekwinai P, Park H, Wang YH, Wang YH, Chang SH, Corry DB, Liu YJ, Zhu Z, Dong C: Interleukin 25 promotes the initiation of proallergic type 2 responses. J Exp Med (2007) 204(7):1509-1517.
-
(2007)
J Exp Med
, vol.204
, Issue.7
, pp. 1509-1517
-
-
Angkasekwinai, P.1
Park, H.2
Wang, Y.H.3
Wang, Y.H.4
Chang, S.H.5
Corry, D.B.6
Liu, Y.J.7
Zhu, Z.8
Dong, C.9
-
44
-
-
75749149721
-
Thymic stromal lymphopoietin
-
He R, Geha RS: Thymic stromal lymphopoietin. Ann NY Acad Sci (2010) 1183:13-24.
-
(2010)
Ann NY Acad Sci
, vol.1183
, pp. 13-24
-
-
He, R.1
Geha, R.S.2
-
45
-
-
45949089317
-
Pivotal a dvance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation
-
Shao DD, Suresh R, Vakil V, Gomer RH, Pilling D: Pivotal a dvance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation. J Leukoc Biol (2008) 83(6):1323-1333.
-
(2008)
J Leukoc Biol
, vol.83
, Issue.6
, pp. 1323-1333
-
-
Shao, D.D.1
Suresh, R.2
Vakil, V.3
Gomer, R.H.4
Pilling, D.5
-
46
-
-
0025998184
-
Fibroblast chemotaxis induction by human recombinant interleukin-4. Identification by synthetic peptide analysis of two chemotactic domains residing in amino acid sequences 70-88 and 89-122
-
Postlethwaite AE, Seyer JM: Fibroblast chemotaxis induction by human recombinant interleukin-4. Identification by synthetic peptide analysis of two chemotactic domains residing in amino acid sequences 70-88 and 89-122. J Clin Invest (1991) 87(6):2147-2152.
-
(1991)
J Clin Invest
, vol.87
, Issue.6
, pp. 2147-2152
-
-
Postlethwaite, A.E.1
Seyer, J.M.2
-
47
-
-
0032697042
-
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response
-
Chiaramonte MG, Donaldson DD, Cheever AW, Wynn TA: An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response. J Clin Invest (1999) 104(6):777-785.
-
(1999)
J Clin Invest
, vol.104
, Issue.6
, pp. 777-785
-
-
Chiaramonte, M.G.1
Donaldson, D.D.2
Cheever, A.W.3
Wynn, T.A.4
-
48
-
-
1642333177
-
Protection from fluorescein isothiocyanate-induced fibrosis in IL-13- deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts
-
Kolodsick JE, Toews GB, Jakubzick C, Hogaboam C, Moore TA, McKenzie A, Wilke CA, Chrisman CJ, Moore BB: Protection from fluorescein isothiocyanate-induced fibrosis in IL-13- deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts. J Immunol (2004) 172(7): 4068-4076.
-
(2004)
J Immunol
, vol.172
, Issue.7
, pp. 4068-4076
-
-
Kolodsick, J.E.1
Toews, G.B.2
Jakubzick, C.3
Hogaboam, C.4
Moore, T.A.5
McKenzie, A.6
Wilke, C.A.7
Chrisman, C.J.8
Moore, B.B.9
-
49
-
-
0036174529
-
STAT6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma
-
Blease K, Schuh JM, Jakubzick C, Lukacs NW, Kunkel SL, Joshi BH, Puri RK, Kaplan MH, Hogaboam CM: STAT6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma. Am J Pathol (2002) 160(2):481-490.
-
(2002)
Am J Pathol
, vol.160
, Issue.2
, pp. 481-490
-
-
Blease, K.1
Schuh, J.M.2
Jakubzick, C.3
Lukacs, N.W.4
Kunkel, S.L.5
Joshi, B.H.6
Puri, R.K.7
Kaplan, M.H.8
Hogaboam, C.M.9
-
50
-
-
30044449492
-
IL-13 signaling through the IL-13α2 receptor is involved in induction of TGF-β1 production and fibrosis
-
Fichtner-Feigl S, Strober W, Kawakami K, Puri RK, Kitani A: IL-13 signaling through the IL-13α2 receptor is involved in induction of TGF-β1 production and fibrosis. Nat Med (2006) 12(1):99-106.
-
(2006)
Nat Med
, vol.12
, Issue.1
, pp. 99-106
-
-
Fichtner-Feigl, S.1
Strober, W.2
Kawakami, K.3
Puri, R.K.4
Kitani, A.5
-
51
-
-
33644756520
-
Interleukin-5 (IL-5) augments the progression of liver fibrosis by regulating IL-13 activity
-
Reiman RM, Thompson RW, Feng CG, Hari D, Knight R, Cheever AW, Rosenberg HF, Wynn TA: Interleukin-5 (IL-5) augments the progression of liver fibrosis by regulating IL-13 activity. Infect Immun (2006) 74(3):1471-1479.
-
(2006)
Infect Immun
, vol.74
, Issue.3
, pp. 1471-1479
-
-
Reiman, R.M.1
Thompson, R.W.2
Feng, C.G.3
Hari, D.4
Knight, R.5
Cheever, A.W.6
Rosenberg, H.F.7
Wynn, T.A.8
-
52
-
-
33745840137
-
The IL-21 receptor augments Th2 effector function and alternative macrophage activation
-
Pesce J, Kaviratne M, Ramalingam TR, Thompson RW, Urban JF Jr, Cheever AW, Young DA, Collins M, Grusby MJ, Wynn TA: The IL-21 receptor augments Th2 effector function and alternative macrophage activation. J Clin Invest (2006) 116(7):2044-2055.
-
(2006)
J Clin Invest
, vol.116
, Issue.7
, pp. 2044-2055
-
-
Pesce, J.1
Kaviratne, M.2
Ramalingam, T.R.3
Thompson, R.W.4
Urban Jr., J.F.5
Cheever, A.W.6
Young, D.A.7
Collins, M.8
Grusby, M.J.9
Wynn, T.A.10
-
53
-
-
77949311799
-
IL-33 induces IL-13-dependent cutaneous fibrosis
-
Rankin AL, Mumm JB, Murphy E, Turner S, Yu N, McClanahan TK, Bourne PA, Pierce RH, Kastelein R, Pflanz S: IL-33 induces IL-13-dependent cutaneous fibrosis. J Immunol (2010) 184(3):1526-1535.
-
(2010)
J Immunol
, vol.184
, Issue.3
, pp. 1526-1535
-
-
Rankin, A.L.1
Mumm, J.B.2
Murphy, E.3
Turner, S.4
Yu, N.5
McClanahan, T.K.6
Bourne, P.A.7
Pierce, R.H.8
Kastelein, R.9
Pflanz, S.10
-
54
-
-
0242405834
-
Potential action of IL-4 and IL-13 as fibrogenic factors on lung fibroblasts in vitro
-
Saito A, Okazaki H, Sugawara I, Yamamoto K, Takizawa H: Potential action of IL-4 and IL-13 as fibrogenic factors on lung fibroblasts in vitro. Int Arch Allergy Immunol (2003) 132(2):168-176.
-
(2003)
Int Arch Allergy Immunol
, vol.132
, Issue.2
, pp. 168-176
-
-
Saito, A.1
Okazaki, H.2
Sugawara, I.3
Yamamoto, K.4
Takizawa, H.5
-
55
-
-
34547960749
-
The role of the fibrocyte, a bone marrowderived mesenchymal progenitor, in reactive and reparative fibroses
-
Bellini A, Mattoli S: The role of the fibrocyte, a bone marrowderived mesenchymal progenitor, in reactive and reparative fibroses. Lab Invest (2007) 87(9):858-870.
-
(2007)
Lab Invest
, vol.87
, Issue.9
, pp. 858-870
-
-
Bellini, A.1
Mattoli, S.2
-
56
-
-
0035052521
-
Interleukin-9 reduces lung fibrosis and type 2 immune polarization induced by silica particles in a murine model
-
Arras M, Huaux F, Vink A, Delos M, Coutelier JP, Many MC, Barbarin V, Renauld JC, Lison D: Interleukin-9 reduces lung fibrosis and type 2 immune polarization induced by silica particles in a murine model. Am J Respir Cell Mol Biol (2001) 24(4):368-375.
-
(2001)
Am J Respir Cell Mol Biol
, vol.24
, Issue.4
, pp. 368-375
-
-
Arras, M.1
Huaux, F.2
Vink, A.3
Delos, M.4
Coutelier, J.P.5
Many, M.C.6
Barbarin, V.7
Renauld, J.C.8
Lison, D.9
-
57
-
-
34547857815
-
Profibrotic effect of IL-9 overexpression in a model of airway remodeling
-
van den Brle S, Heymans J, Havaux X, Renauld JC, Lison D, Huaux F, Denis O: Profibrotic effect of IL-9 overexpression in a model of airway remodeling. Am J Respir Cell Mol Biol (2007) 37(2):202-209.
-
(2007)
Am J Respir Cell Mol Biol
, vol.37
, Issue.2
, pp. 202-209
-
-
Van Den Brle, S.1
Heymans, J.2
Havaux, X.3
Renauld, J.C.4
Lison, D.5
Huaux, F.6
Denis, O.7
-
58
-
-
3543107212
-
Fibrotic disease and the Th1/Th2 paradigm
-
Wynn TA: Fibrotic disease and the Th1/Th2 paradigm. Nat Rev Immunol (2004)4(8):583-594.
-
(2004)
Nat Rev Immunol
, vol.4
, Issue.8
, pp. 583-594
-
-
Wynn, T.A.1
-
59
-
-
77950442739
-
IPF: New insight on pathogenesis and treatment
-
Harari S, Caminati A: IPF: New insight on pathogenesis and treatment. Allergy (2010) 65(5):537-553.
-
(2010)
Allergy
, vol.65
, Issue.5
, pp. 537-553
-
-
Harari, S.1
Caminati, A.2
-
60
-
-
0018629834
-
Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse
-
Szapiel SV, Elson NA, Fulmer JD, Hunninghake GW, Crystal RG: Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse. Am Rev Respir Dis (1979) 120(4):893-899.
-
(1979)
Am Rev Respir Dis
, vol.120
, Issue.4
, pp. 893-899
-
-
Szapiel, S.V.1
Elson, N.A.2
Fulmer, J.D.3
Hunninghake, G.W.4
Crystal, R.G.5
-
61
-
-
0032982694
-
T cell independence of bleomycin-induced pulmonary fibrosis
-
Helene M, Lake-Bullock V, Zhu J, Hao H, Cohen DA, Kaplan AM: T cell independence of bleomycin-induced pulmonary fibrosis. J Leukoc Biol (1999) 65(2):187-195.
-
(1999)
J Leukoc Biol
, vol.65
, Issue.2
, pp. 187-195
-
-
Helene, M.1
Lake-Bullock, V.2
Zhu, J.3
Hao, H.4
Cohen, D.A.5
Kaplan, A.M.6
-
62
-
-
0024414604
-
Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis
-
Piguet PF, Collart MA, Grau GE, Kapanci Y, Vassalli P: Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis. J Exp Med (1989) 170(3):655-663.
-
(1989)
J Exp Med
, vol.170
, Issue.3
, pp. 655-663
-
-
Piguet, P.F.1
Collart, M.A.2
Grau, G.E.3
Kapanci, Y.4
Vassalli, P.5
-
63
-
-
0020618189
-
The effects of the nude (nu/nu) mutation on bleomycin-induced pulmonary fibrosis. A biochemical evaluation
-
Schrier DJ, Phan SH, McGarry BM: The effects of the nude (nu/nu) mutation on bleomycin-induced pulmonary fibrosis. A biochemical evaluation. Am Rev Respir Dis (1983) 127(5): 614-617.
-
(1983)
Am Rev Respir Dis
, vol.127
, Issue.5
, pp. 614-617
-
-
Schrier, D.J.1
Phan, S.H.2
McGarry, B.M.3
-
64
-
-
0035881824
-
Impairment of bleomycin-induced lung fibrosis in CD28-deficient mice
-
Okazaki T, Nakao A, Nakano H, Takahashi F, Takahashi K, Shimozato O, Takeda K, Yagita H, Okumura K: Impairment of bleomycin-induced lung fibrosis in CD28-deficient mice. J Immunol (2001) 167(4):1977-1981.
-
(2001)
J Immunol
, vol.167
, Issue.4
, pp. 1977-1981
-
-
Okazaki, T.1
Nakao, A.2
Nakano, H.3
Takahashi, F.4
Takahashi, K.5
Shimozato, O.6
Takeda, K.7
Yagita, H.8
Okumura, K.9
-
65
-
-
33745714809
-
Overexpression of the transcription factor GATA-3 enhances the development of pulmonary fibrosis
-
Kimura T, Ishii Y, Yoh K, Morishima Y, Iizuka T, Kiwamoto T, Matsuno Y, Homma S, Nomura A, Sakamoto T, Takahashi S et al: Overexpression of the transcription factor GATA-3 enhances the development of pulmonary fibrosis. Am J Pathol (2006) 169(1):96-104.
-
(2006)
Am J Pathol
, vol.169
, Issue.1
, pp. 96-104
-
-
Kimura, T.1
Ishii, Y.2
Yoh, K.3
Morishima, Y.4
Iizuka, T.5
Kiwamoto, T.6
Matsuno, Y.7
Homma, S.8
Nomura, A.9
Sakamoto, T.10
Takahashi, S.11
-
66
-
-
33749337453
-
Increased bleomycin-induced lung injury in mice deficient in the transcription factor T-bet
-
Xu J, Mora AL, LaVoy J, Brigham KL, Rojas M: Increased bleomycin-induced lung injury in mice deficient in the transcription factor T-bet. Am J Physiol Lung Cell Mol Physiol (2006) 291(4):L658-L667.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
, Issue.4
-
-
Xu, J.1
Mora, A.L.2
Lavoy, J.3
Brigham, K.L.4
Rojas, M.5
-
67
-
-
77952525647
-
Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance
-
Kikuchi N, Ishii Y, Morishima Y, Yageta Y, Haraguchi N, Itoh K, Yamamoto M, Hizawa N: Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance. Respir Res (2010) 11:31.
-
(2010)
Respir Res
, vol.11
, pp. 31
-
-
Kikuchi, N.1
Ishii, Y.2
Morishima, Y.3
Yageta, Y.4
Haraguchi, N.5
Itoh, K.6
Yamamoto, M.7
Hizawa, N.8
-
68
-
-
27144521409
-
Relationship of BAL and lung tissue CD4+ and CD8+ T lymphocytes, and their ratio in idiopathic pulmonary fibrosis
-
Papiris SA, Kollintza A, Kitsanta P, Kapotsis G, Karatza M, Milic-Emili J, Roussos C, Daniil Z: Relationship of BAL and lung tissue CD4+ and CD8+ T lymphocytes, and their ratio in idiopathic pulmonary fibrosis. Chest (2005) 128(4):2971-2977.
-
(2005)
Chest
, vol.128
, Issue.4
, pp. 2971-2977
-
-
Papiris, S.A.1
Kollintza, A.2
Kitsanta, P.3
Kapotsis, G.4
Karatza, M.5
Milic-Emili, J.6
Roussos, C.7
Daniil, Z.8
-
69
-
-
32144452037
-
Role of the chemokine receptors CXCR3 and CCR4 in human pulmonary fibrosis
-
Pignatti P, Brunetti G, Moretto D, Yacoub MR, Fiori M, Balbi B, Balestrino A, Cervio G, Nava S, Moscato G: Role of the chemokine receptors CXCR3 and CCR4 in human pulmonary fibrosis. Am J Respir Crit Care Med (2006) 173(3):310-317.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, Issue.3
, pp. 310-317
-
-
Pignatti, P.1
Brunetti, G.2
Moretto, D.3
Yacoub, M.R.4
Fiori, M.5
Balbi, B.6
Balestrino, A.7
Cervio, G.8
Nava, S.9
Moscato, G.10
-
71
-
-
0025514183
-
Myofibroblasts and subepithelial fibrosis in bronchial asthma
-
Brewster CE, Howarth PH, Djukanovic R, Wilson J, Holgate ST, Roche WR: Myofibroblasts and subepithelial fibrosis in bronchial asthma. Am J Respir Cell Mol Biol (1990) 3(5):507-511.
-
(1990)
Am J Respir Cell Mol Biol
, vol.3
, Issue.5
, pp. 507-511
-
-
Brewster, C.E.1
Howarth, P.H.2
Djukanovic, R.3
Wilson, J.4
Holgate, S.T.5
Roche, W.R.6
-
72
-
-
1642529528
-
Type 2 cytokines in the pathogenesis of sustained airway dysfunction and airway remodeling in mice
-
Leigh R, Ellis R, Wattie JN, Hirota JA, Matthaei KI, Foster PS, O'Byrne PM, Inman MD: Type 2 cytokines in the pathogenesis of sustained airway dysfunction and airway remodeling in mice. Am J Respir Crit Care Med (2004) 169(7):860-867.
-
(2004)
Am J Respir Crit Care Med
, vol.169
, Issue.7
, pp. 860-867
-
-
Leigh, R.1
Ellis, R.2
Wattie, J.N.3
Hirota, J.A.4
Matthaei, K.I.5
Foster, P.S.6
O'Byrne, P.M.7
Inman, M.D.8
-
73
-
-
0037338023
-
Transgenic modeling of interleukin-13 in the lung
-
Elias JA, Zheng T, Lee CG, Homer RJ, Chen Q, Ma B, Blackburn M, Zhu Z: Transgenic modeling of interleukin-13 in the lung. Chest (2003) 123(3 Suppl):339S-345S.
-
(2003)
Chest
, vol.123
, Issue.3 SUPPL.
-
-
Elias, J.A.1
Zheng, T.2
Lee, C.G.3
Homer, R.J.4
Chen, Q.5
Ma, B.6
Blackburn, M.7
Zhu, Z.8
-
74
-
-
33745748325
-
Transcription factors T-bet and GATA-3 regulate development of airway remodeling
-
Kiwamoto T, Ishii Y, Morishima Y, Yoh K, Maeda A, Ishizaki K, Iizuka T, Hegab AE, Matsuno Y, Homma S, Nomura A et al: Transcription factors T-bet and GATA-3 regulate development of airway remodeling. Am J Respir Crit Care Med (2006) 174(2):142-151.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, Issue.2
, pp. 142-151
-
-
Kiwamoto, T.1
Ishii, Y.2
Morishima, Y.3
Yoh, K.4
Maeda, A.5
Ishizaki, K.6
Iizuka, T.7
Hegab, A.E.8
Matsuno, Y.9
Homma, S.10
Nomura, A.11
-
75
-
-
70349562495
-
Mononuclear cells in liver fibrosis
-
Marra F, Aleffi S, Galastri S, Provenzano A: Mononuclear cells in liver fibrosis. Semin Immunopathol (2009) 31(3):345-358
-
(2009)
Semin Immunopathol
, vol.31
, Issue.3
, pp. 345-358
-
-
Marra, F.1
Aleffi, S.2
Galastri, S.3
Provenzano, A.4
-
76
-
-
0030885185
-
Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses
-
Shi Z, Wakil AE, Rockey DC: Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses. Proc Natl Acad Sci USA (1997) 94(20):10663-10668.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.20
, pp. 10663-10668
-
-
Shi, Z.1
Wakil, A.E.2
Rockey, D.C.3
-
77
-
-
0029887586
-
Interferon γ decreases hepatic stellate cell activation and extracellular matrix deposition in rat liver fibrosis
-
Baroni GS, D'Ambrosio L, Curto P, Casini A, Mancini R, Jezequel AM, Benedetti A: Interferon γ decreases hepatic stellate cell activation and extracellular matrix deposition in rat liver fibrosis. Hepatology (1996) 23(5):1189-1199.
-
(1996)
Hepatology
, vol.23
, Issue.5
, pp. 1189-1199
-
-
Baroni, G.S.1
D'Ambrosio, L.2
Curto, P.3
Casini, A.4
Mancini, R.5
Jezequel, A.M.6
Benedetti, A.7
-
78
-
-
0029142790
-
An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection
-
Wynn TA, Cheever AW, Jankovic D, Poindexter RW, Caspar P, Lewis FA, Sher A: An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection. Nature (1995) 376(6541):594-596.
-
(1995)
Nature
, vol.376
, Issue.6541
, pp. 594-596
-
-
Wynn, T.A.1
Cheever, A.W.2
Jankovic, D.3
Poindexter, R.W.4
Caspar, P.5
Lewis, F.A.6
Sher, A.7
-
79
-
-
0028363023
-
Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis
-
Cheever AW, Williams ME, Wynn TA, Finkelman FD, Seder RA, Cox TM, Hieny S, Caspar P, Sher A: Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis. J Immunol (1994) 153(2):753-759.
-
(1994)
J Immunol
, vol.153
, Issue.2
, pp. 753-759
-
-
Cheever, A.W.1
Williams, M.E.2
Wynn, T.A.3
Finkelman, F.D.4
Seder, R.A.5
Cox, T.M.6
Hieny, S.7
Caspar, P.8
Sher, A.9
-
80
-
-
0034923170
-
Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis
-
Chiaramonte MG, Cheever AW, Malley JD, Donaldson DD, Wynn TA: Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis. Hepatology (2001) 34(2):273-282.
-
(2001)
Hepatology
, vol.34
, Issue.2
, pp. 273-282
-
-
Chiaramonte, M.G.1
Cheever, A.W.2
Malley, J.D.3
Donaldson, D.D.4
Wynn, T.A.5
-
81
-
-
33847324516
-
Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13
-
Aliprantis AO, Wang J, Fathman JW, Lemaire R, Dorfman DM, Lafyatis R, Glimcher LH: Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13. Proc Natl Acad Sci USA (2007) 104(8):2827-2830.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.8
, pp. 2827-2830
-
-
Aliprantis, A.O.1
Wang, J.2
Fathman, J.W.3
Lemaire, R.4
Dorfman, D.M.5
Lafyatis, R.6
Glimcher, L.H.7
-
82
-
-
56249112642
-
T cells, B cells, and polarized immune response in the pathogenesis of fibrosis and systemic sclerosis
-
Chizzolini C: T cells, B cells, and polarized immune response in the pathogenesis of fibrosis and systemic sclerosis. Curr Opin Rheumatol (2008) 20(6):707-712.
-
(2008)
Curr Opin Rheumatol
, vol.20
, Issue.6
, pp. 707-712
-
-
Chizzolini, C.1
-
83
-
-
72949097179
-
Frequency of Th1, Th2 and Th17 producing T lymphocytes in bronchoalveolar lavage of patients with systemic sclerosis
-
Meloni F, Solari N, Cavagna L, Morosini M, Montecucco CM, Fietta AM: Frequency of Th1, Th2 and Th17 producing T lymphocytes in bronchoalveolar lavage of patients with systemic sclerosis. Clin Exp Rheumatol (2009) 27(5):765-772.
-
(2009)
Clin Exp Rheumatol
, vol.27
, Issue.5
, pp. 765-772
-
-
Meloni, F.1
Solari, N.2
Cavagna, L.3
Morosini, M.4
Montecucco, C.M.5
Fietta, A.M.6
-
84
-
-
0027433763
-
Glucocorticoid therapy for immune-mediated diseases: Basic and clinical correlates
-
Boumpas DT, Chrousos GP, Wilder RL, Cupps TR, Balow JE: Glucocorticoid therapy for immune-mediated diseases: Basic and clinical correlates. Ann Intern Med (1993) 119(12): 1198-1208.
-
(1993)
Ann Intern Med
, vol.119
, Issue.12
, pp. 1198-1208
-
-
Boumpas, D.T.1
Chrousos, G.P.2
Wilder, R.L.3
Cupps, T.R.4
Balow, J.E.5
-
85
-
-
0029124143
-
Molecular mechanisms of antifibrotic effect of interferon γ in bleomycin-mouse model of lung fibrosis: Downregulation of TGF-β and procollagen i and III gene expression
-
Gurujeyalakshmi G, Giri SN: Molecular mechanisms of antifibrotic effect of interferon γ in bleomycin-mouse model of lung fibrosis: Downregulation of TGF-β and procollagen I and III gene expression. Exp Lung Res (1995) 21(5):791-808.
-
(1995)
Exp Lung Res
, vol.21
, Issue.5
, pp. 791-808
-
-
Gurujeyalakshmi, G.1
Giri, S.N.2
-
86
-
-
0033452097
-
Interferon-γ inhibits experimental renal fibrosis
-
Oldroyd SD, Thomas GL, Gabbiani G, El Nahas AM: Interferon-γ inhibits experimental renal fibrosis. Kidney Int (1999) 56(6): 2116-2127.
-
(1999)
Kidney Int
, vol.56
, Issue.6
, pp. 2116-2127
-
-
Oldroyd, S.D.1
Thomas, G.L.2
Gabbiani, G.3
El Nahas, A.M.4
-
87
-
-
0033918460
-
Effect of interferon-gamma on experimental scleroderma induced by bleomycin
-
Yamamoto T, Takagawa S, Kuroda M, Nishioka K: Effect of interferon-gamma on experimental scleroderma induced by bleomycin. Arch Dermatol Res (2000) 292(7):362-365.
-
(2000)
Arch Dermatol Res
, vol.292
, Issue.7
, pp. 362-365
-
-
Yamamoto, T.1
Takagawa, S.2
Kuroda, M.3
Nishioka, K.4
-
89
-
-
8444245228
-
Effects of anticytokine therapy in a mouse model of chronic asthma
-
Kumar RK, Herbert C, Webb DC, Li L, Foster PS: Effects of anticytokine therapy in a mouse model of chronic asthma. Am J Respir Crit Care Med (2004) 170(10):1043-1048.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, Issue.10
, pp. 1043-1048
-
-
Kumar, R.K.1
Herbert, C.2
Webb, D.C.3
Li, L.4
Foster, P.S.5
-
90
-
-
22244460509
-
Interferon-γ1b therapy in idiopathic pulmonary fibrosis: A metaanalysis
-
Bajwa EK, Ayas NT, Schulzer M, Mak E, Ryu JH, Malhotra A: Interferon-γ1b therapy in idiopathic pulmonary fibrosis: A metaanalysis. Chest (2005) 128(1):203-206.
-
(2005)
Chest
, vol.128
, Issue.1
, pp. 203-206
-
-
Bajwa, E.K.1
Ayas, N.T.2
Schulzer, M.3
Mak, E.4
Ryu, J.H.5
Malhotra, A.6
-
91
-
-
0345824715
-
Idiopathic Pulmonary Fibrosis Study Group: A placebo-controlled trial of interferon γ-1b in patients with idiopathic pulmonary fibrosis
-
Raghu G, Brown KK, Bradford WZ, Starko K, Noble PW, Schwartz DA, King TE Jr, Idiopathic Pulmonary Fibrosis Study Group: A placebo-controlled trial of interferon γ-1b in patients with idiopathic pulmonary fibrosis. N Engl J Med (2004) 350(2):125-133.
-
(2004)
N Engl J Med
, vol.350
, Issue.2
, pp. 125-133
-
-
Raghu, G.1
Brown, K.K.2
Bradford, W.Z.3
Starko, K.4
Noble, P.W.5
Schwartz, D.A.6
King Jr., T.E.7
-
92
-
-
67650349068
-
Effect of interferon γ-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): A multicentre, randomised, placebo-controlled trial
-
King TE Jr, Albera C, Bradford WZ, Costabel U, Hormel P, Lancaster L, Noble PW, Sahn SA, Szwarcberg J, Thomeer M, Valeyre D et al: Effect of interferon γ-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): A multicentre, randomised, placebo-controlled trial. Lancet (2009) 374(9685):222-228.
-
(2009)
Lancet
, vol.374
, Issue.9685
, pp. 222-228
-
-
King Jr., T.E.1
Albera, C.2
Bradford, W.Z.3
Costabel, U.4
Hormel, P.5
Lancaster, L.6
Noble, P.W.7
Sahn, S.A.8
Szwarcberg, J.9
Thomeer, M.10
Valeyre, D.11
-
93
-
-
33947362952
-
Final results of a double-blind, placebocontrolled trial of the antifibrotic efficacy of interferon-γ1b in chronic hepatitis C patients with advanced fibrosis or cirrhosis
-
Pockros PJ, Jeffers L, Afdhal N, Goodman ZD, Nelson D, Gish RG, Reddy KR, Reindollar R, Rodriguez-Torres M, Sullivan S, Blatt LM et al: Final results of a double-blind, placebocontrolled trial of the antifibrotic efficacy of interferon-γ1b in chronic hepatitis C patients with advanced fibrosis or cirrhosis. Hepatology (2007) 45(3):569-578.
-
(2007)
Hepatology
, vol.45
, Issue.3
, pp. 569-578
-
-
Pockros, P.J.1
Jeffers, L.2
Afdhal, N.3
Goodman, Z.D.4
Nelson, D.5
Gish, R.G.6
Reddy, K.R.7
Reindollar, R.8
Rodriguez-Torres, M.9
Sullivan, S.10
Blatt, L.M.11
-
94
-
-
0024431095
-
Recombinant interferon-γ in the treatment of systemic sclerosis
-
Kahan A, Amor B, Menkes CJ, Strauch G: Recombinant interferon-γ in the treatment of systemic sclerosis. Am J Med (1989) 87(3):273-277.
-
(1989)
Am J Med
, vol.87
, Issue.3
, pp. 273-277
-
-
Kahan, A.1
Amor, B.2
Menkes, C.J.3
Strauch, G.4
-
95
-
-
0029853101
-
Safety and efficacy of recombinant γ interferon in the treatment of systemic sclerosis
-
Vlachoyiannopoulos PG, Tsifetaki N, Dimitriou I, Galaris D, Papiris SA, Moutsopoulos HM: Safety and efficacy of recombinant γ interferon in the treatment of systemic sclerosis. Ann Rheum Dis (1996) 55(10):761-768.
-
(1996)
Ann Rheum Dis
, vol.55
, Issue.10
, pp. 761-768
-
-
Vlachoyiannopoulos, P.G.1
Tsifetaki, N.2
Dimitriou, I.3
Galaris, D.4
Papiris, S.A.5
Moutsopoulos, H.M.6
-
96
-
-
7844237877
-
Interferon-γ in the treatment of systemic sclerosis: A randomized controlled multicentre trial
-
Grassegger A, Schuler G, Hessenberger G, Walder-Hantich B, Jabkowski J, MacHeiner W, Salmhofer W, Zahel B, Pinter G, Herold M, Klein G et al: Interferon-γ in the treatment of systemic sclerosis: A randomized controlled multicentre trial. Br J Dermatol (1998) 139(4):639-648.
-
(1998)
Br J Dermatol
, vol.139
, Issue.4
, pp. 639-648
-
-
Grassegger, A.1
Schuler, G.2
Hessenberger, G.3
Walder-Hantich, B.4
Jabkowski, J.5
MacHeiner, W.6
Salmhofer, W.7
Zahel, B.8
Pinter, G.9
Herold, M.10
Klein, G.11
-
97
-
-
0029878115
-
A multicenter trial of recombinant human interferon gamma in patients with systemic sclerosis: Effects on cutaneous fibrosis and interleukin 2 receptor levels
-
Polisson RP, Gilkeson GS, Pyun EH, Pisetsky DS, Smith EA, Simon LS: A multicenter trial of recombinant human interferon gamma in patients with systemic sclerosis: Effects on cutaneous fibrosis and interleukin 2 receptor levels. J Rheumatol (1996) 23(4):654-658.
-
(1996)
J Rheumatol
, vol.23
, Issue.4
, pp. 654-658
-
-
Polisson, R.P.1
Gilkeson, G.S.2
Pyun, E.H.3
Pisetsky, D.S.4
Smith, E.A.5
Simon, L.S.6
-
98
-
-
0034995872
-
IL-4R Asthma Study Group: Efficacy of soluble IL-4 receptor for the treatment of adults with asthma
-
Borish LC, Nelson HS, Corren J, Bensch G, Busse WW, Whitmore JB, Agosti JM, IL-4R Asthma Study Group: Efficacy of soluble IL-4 receptor for the treatment of adults with asthma. J Allergy Clin Immunol (2001) 107(6):963-970.
-
(2001)
J Allergy Clin Immunol
, vol.107
, Issue.6
, pp. 963-970
-
-
Borish, L.C.1
Nelson, H.S.2
Corren, J.3
Bensch, G.4
Busse, W.W.5
Whitmore, J.B.6
Agosti, J.M.7
-
99
-
-
35348909044
-
Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: Results of two phase 2a studies
-
Wenzel S, Wilbraham D, Fuller R, Getz EB, Longphre M: Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: Results of two phase 2a studies. Lancet (2007) 370(9596):1422-1431.
-
(2007)
Lancet
, vol.370
, Issue.9596
, pp. 1422-1431
-
-
Wenzel, S.1
Wilbraham, D.2
Fuller, R.3
Getz, E.B.4
Longphre, M.5
-
100
-
-
0038643527
-
Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: A pilot study
-
Kips JC, O'Connor BJ, Langley SJ, Woodcock A, Kerstjens HA, Postma DS, Danzig M, Cuss F, Pauwels RA: Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: A pilot study. Am J Respir Crit Care Med (2003) 167(12):1655-1659.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, Issue.12
, pp. 1655-1659
-
-
Kips, J.C.1
O'Connor, B.J.2
Langley, S.J.3
Woodcock, A.4
Kerstjens, H.A.5
Postma, D.S.6
Danzig, M.7
Cuss, F.8
Pauwels, R.A.9
-
101
-
-
2942560685
-
Intravenous anti-IL-5 monoclonal antibody reduces eosinophils and tenascin deposition in allergen-challenged human atopic skin
-
Phipps S, Flood-Page P, Menzies-Gow A, Ong YE, Kay AB: Intravenous anti-IL-5 monoclonal antibody reduces eosinophils and tenascin deposition in allergen-challenged human atopic skin. J Invest Dermatol (2004) 122(6):1406-1412.
-
(2004)
J Invest Dermatol
, vol.122
, Issue.6
, pp. 1406-1412
-
-
Phipps, S.1
Flood-Page, P.2
Menzies-Gow, A.3
Ong, Y.E.4
Kay, A.B.5
-
102
-
-
85047693849
-
Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
-
Flood-Page P, Menzies-Gow A, Phipps S, Ying S, Wangoo A, Ludwig MS, Barnes N, Robinson D, Kay AB: Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Invest (2003) 112(7):1029-1036.
-
(2003)
J Clin Invest
, vol.112
, Issue.7
, pp. 1029-1036
-
-
Flood-Page, P.1
Menzies-Gow, A.2
Phipps, S.3
Ying, S.4
Wangoo, A.5
Ludwig, M.S.6
Barnes, N.7
Robinson, D.8
Kay, A.B.9
-
103
-
-
76749141384
-
A phase 1 study evaluating the pharmacokinetics, safety and tolerability of repeat dosing with a human IL-13 antibody (CAT-354) in subjects with asthma
-
Singh D, Kane B, Molfino NA, Faggioni R, Roskos L, Woodcock A: A phase 1 study evaluating the pharmacokinetics, safety and tolerability of repeat dosing with a human IL-13 antibody (CAT-354) in subjects with asthma. BMC Pulm Med (2010) 10:3.
-
(2010)
BMC Pulm Med
, vol.10
, pp. 3
-
-
Singh, D.1
Kane, B.2
Molfino, N.A.3
Faggioni, R.4
Roskos, L.5
Woodcock, A.6
-
104
-
-
77953039047
-
A randomized, controlled, phase 2 study of AMG 317, an IL-4Rα antagonist, in patients with asthma
-
Corren J, Busse W, Meltzer EO, Mansfield L, Bensch G, Fahrenholz J, Wenzel SE, Chon Y, Dunn M, Weng HH, Lin SL: A randomized, controlled, phase 2 study of AMG 317, an IL-4Rα antagonist, in patients with asthma. Am J Respir Crit Care Med (2010) 181(8):788-796.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, Issue.8
, pp. 788-796
-
-
Corren, J.1
Busse, W.2
Meltzer, E.O.3
Mansfield, L.4
Bensch, G.5
Fahrenholz, J.6
Wenzel, S.E.7
Chon, Y.8
Dunn, M.9
Weng, H.H.10
Lin, S.L.11
-
105
-
-
77649152847
-
Use of biologicals as immunotherapy in asthma and related diseases
-
Walker BL, Leigh R: Use of biologicals as immunotherapy in asthma and related diseases. Expert Rev Clin Immunol (2008) 4(6):743-756.
-
(2008)
Expert Rev Clin Immunol
, vol.4
, Issue.6
, pp. 743-756
-
-
Walker, B.L.1
Leigh, R.2
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