IL-13 signaling through the IL-13α2 receptor is involved in induction of TGF-β1 production and fibrosis

Nature Medicine

Volumn 12, Issue 1, 2006, Pages 99-106

  Fichtner Feigl, Stefan ^a,b   Strober, Warren ^a   Kawakami, Koji ^c   Puri, Raj K ^c   Kitani, Atsushi ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; COLLAGEN; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR ALPHA2; INTERLEUKIN 4; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR FRA 2; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; GENE SILENCING; IN VIVO STUDY; LUNG FIBROSIS; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; BLEOMYCIN; BLOTTING, WESTERN; CELL LINEAGE; COLITIS; COLLAGEN; CYTOKINES; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROSIS; FLOW CYTOMETRY; GENE SILENCING; GENETIC VECTORS; HUMANS; IMMUNOGLOBULIN G; INFLAMMATION; INTERLEUKIN-13; INTERLEUKIN-13 RECEPTOR ALPHA1 SUBUNIT; LUCIFERASES; LUNG; MACROPHAGES; MICE; MICE, INBRED C57BL; MONOCYTES; NF-KAPPA B; OXAZOLONE; PROMOTER REGIONS (GENETICS); RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-13; RECEPTORS, TUMOR NECROSIS FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

ANIMALIA;

EID: 30044449492     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1332     Document Type: Article

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