The Chinese herbal medicine Sophora flavescens activates pregnane X receptor

Drug Metabolism and Disposition

Volumn 38, Issue 12, 2010, Pages 2226-2231

  Wang, Laiyou ^a,b   Li, Feng ^a   Lu, Jie ^a   Li, Guodong ^a   Li, Dan ^a   Zhong, Xiao Bo ^a   Guo, Grace L ^a   Ma, Xiaochao ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A; CYTOCHROME P450 3A4; LUCIFERASE; MECYSTEINE; PREGNANE X RECEPTOR; SOPHORA FLAVESCENS EXTRACT;

ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME REGULATION; GENETIC TRANSFECTION; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL; METABOLOMICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPORTER GENE;

ALKALOIDS; CELL LINE; CYTOCHROME P-450 CYP3A; DRUGS, CHINESE HERBAL; ENZYME INDUCTION; HERB-DRUG INTERACTIONS; HUMANS; QUINOLIZINES; RECEPTORS, STEROID; SOPHORA;

SOPHORA FLAVESCENS;

EID: 78649531917     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.110.035253     Document Type: Article

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