A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system

Journal of Pharmacology and Experimental Therapeutics

Volumn 303, Issue 1, 2002, Pages 412-423

  Raucy, Judy ^a   Warfe, Lyndon ^a   Yueh, Mei Fei ^a   Allen, Scott W ^a  

^a Puracyp Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPACTIN; CYTOCHROME P450 3A4; DIMETHYL SULFOXIDE; LUCIFERASE; MIFEPRISTONE; OMEPRAZOLE; RIFAMPICIN; XENOBIOTIC AGENT;

ADULT; ARTICLE; CELL ASSAY; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INDUCTION; FEMALE; HEPATOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; REPORTER GENE; SOUTHERN BLOTTING; STANDARDIZATION;

BASE SEQUENCE; BLOTTING, NORTHERN; CELL LINE, TRANSFORMED; CELL SURVIVAL; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; ENZYME INDUCTION; GENES, REPORTER; HEPATOCYTES; HUMANS; LIVER; LOVASTATIN; LUCIFERASES; MIFEPRISTONE; MIXED FUNCTION OXYGENASES; OMEPRAZOLE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIFAMPIN; RNA, MESSENGER; TETRACHLORODIBENZODIOXIN; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0036784511     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.038653     Document Type: Article

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