Evaluation of HepaRG cells as an in vitro model for human drug metabolism studies

Drug Metabolism and Disposition

Volumn 36, Issue 7, 2008, Pages 1444-1452

  Kanebratt, Kajsa P ^a,b,c   Andersson, Tommy B ^a,b,c  

^a ASTRAZENECA R AND D   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHOXYCOUMARIN; AMFEBUTAMONE; CARRIER PROTEIN; CHOLESTEROL 7ALPHA MONOOXYGENASE; CLOZAPINE; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2B6; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; DEXTROMETHORPHAN; DICLOFENAC; DIMETHYL SULFOXIDE; GLUCURONOSYLTRANSFERASE; MIDAZOLAM; NALOXONE; PARACETAMOL; PHENACETIN; TRANSCRIPTION FACTOR;

ARTICLE; CELL DIFFERENTIATION; CELL STRAIN HEPARG; CONTROLLED STUDY; DRUG METABOLISM; HEPATOMA CELL; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; LIVER CELL; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION;

CELL DIFFERENTIATION; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; DIMETHYL SULFOXIDE; DRUG EVALUATION, PRECLINICAL; HUMANS; MASS SPECTROMETRY; POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 46449089949     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.020016     Document Type: Article

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