Quinolizidine alkaloids with anti-HBV activity from Sophora tonkinensis

Planta Medica

Volumn 72, Issue 9, 2006, Pages 854-856

  Ding, Pei Lan ^a   Huang, Hai ^a   Zhou, Pei ^a   Chen, Dao Feng ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

14BETA HYDROXYOXYMATRINE; 14BETA YDROXYMATRINE; 5ALPHA HYDROXYSOPHOCARPINE; ALKALOID; ANTIVIRUS AGENT; CAULOPHYLLINE; CYTISINE; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; HERBACEOUS AGENT; MATRINE; OXYMATRINE; PLANT EXTRACT; QUINOLIZIDINE DERIVATIVE; SOPHORA TONKINENSIS EXTRACT; SOPHORANOL; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG INHIBITION; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; HEPATITIS B VIRUS; PLANT ROOT; RHIZOME; SOPHORA; SPECTROSCOPY; STRUCTURE ANALYSIS;

ALKALOIDS; ANTIVIRAL AGENTS; CELL LINE; HEPATITIS B VIRUS; HUMANS; PLANT ROOTS; QUINOLIZINES; SOPHORA;

FABACEAE; HEPATITIS B VIRUS; SOPHORA;

EID: 33747015789     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-946639     Document Type: Article

References (11)

1. Ding PL, Liao ZX, Huang H, Zhou P, Chen DF. (+)-12α- Hydroxysophocarpine, a new quinolizidine alkaloid and related anti-HBV alkaloids from Sophora flavescens. Bioorg Med Chem Lett 2006; 16: 1231-5
2. State Pharmacopoeia Commission of PRC. Pharmacopoeia of the People's Republic of China; Vol. 1 Beijing: Chemical Industry Press, 2005: p 19-20
3. Fan HW, Lu JH, Zhang R. Studies on the antibacterial and antiviral activities of matrine-type alkaloids, and its effect on inducing Interferon production. Zhong Yi Yao Xin Xi 2000; 17: 75-6
4. Xiao P, Li JS, Kubo H, Saito K, Murakoshi I, Ohmiya S. (-)-14β-Hydroxymatrine, a new lupin alkaloid from the roots of Sophora tonkinensis. Chem Pharm Bull 1996; 44: 1951-3
5. Xiao P, Kubo H, Komiya H, Higashiyama K, Yan YN, Li JS et al. (-)-14β-Acetoxymatrine and (+)-14α-acetoxymatrine, two new matrine-type lupin alkaloids from the leaves of Sophora tonkinensis. Chem Pharm Bull 1999; 47: 448-50
6. Zhang LZ, Li JS, Houghton PJ, Jackson S, Twentyman PR. Alkaloids in Sophora alopecuroides seed and relevant tests for activity. Zhongguo Zhong Yao Za Zhi 1997; 22: 740-3
7. Zhao YY, Pang QY, Liu JB, Chen YY, Lou ZC. Studies on the alkaloids of Sophora flavescens. Tian Ran Chan Wu Yan Jiu Yu Kai Fa 1994; 6: 10-3
8. Saito K, Arai N, Sekine T, Ohmiya S, Kubo H, Otomasu H et al. (-)-5α-Hydroxysophocarpine, a new lupin alkaloid from the seeds of Sophora flavescens var. angustifolia. Planta Med 1990; 56: 487-8
9. Takamatsu S, Saito K, Ohmiya S, Ruangrungsi N, Murakoshi I. Lupin alkaloids from Sophora exigua. Phytochemistry 1991; 30: 3793-5
10. Ding PL, Chen DF. The pharmacological activities, clinical applications and side effects of the Chinese drug 'Shan-dou-gen' and its preparations. Zhongguo Lin Chuang Yao Xue Za Zhi 2003; 12: 315-8
11. Wu T, Huang H, Zhou P. The inhibitory effects of enduracidin on hepatitis B virus in vitro. Zhongguo Bing Du Xue 1998; 13: 45-9