Passenger mutations as a marker of clonal cell lineages in emerging neoplasia

Seminars in Cancer Biology

Volumn 20, Issue 5, 2010, Pages 294-303

  Salk, Jesse J ^a   Horwitz, Marshall S ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Biomarker; Cancer genome; Clonal evolution; Field cancerization; Field defect; Field effect; Preneoplastic; Somatic evolution

Indexed keywords

CYTOCHROME C OXIDASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MITOCHONDRIAL DNA;

CANCER DIAGNOSIS; CANCER SUSCEPTIBILITY; CELL LINEAGE; CLONAL VARIATION; EARLY DIAGNOSIS; EPIGENETICS; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; GENETIC VARIABILITY; GENOMICS; GENOTYPE; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; LEIOMYOMA; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MITOCHONDRIAL GENOME; MUTATIONAL ANALYSIS; POINT MUTATION; REVIEW; SHORT TANDEM REPEAT; SOMATIC MUTATION; X CHROMOSOME INACTIVATION;

CELL LINEAGE; CLONE CELLS; DNA METHYLATION; DNA MISMATCH REPAIR; EARLY DETECTION OF CANCER; GENETIC VARIATION; GENOME, MITOCHONDRIAL; HUMANS; MICROSATELLITE INSTABILITY; MUTATION; NEOPLASMS;

EID: 78649457137     PISSN: 1044579X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semcancer.2010.10.008     Document Type: Review

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