Multiple head and neck tumors: Evidence for a common clonal origin

Cancer Research

Volumn 56, Issue 11, 1996, Pages 2484-2487

  Bedi, Gauri C ^a   Westra, William H ^a   Gabrielson, Edward ^a   Koch, Wayne ^a   Sidransky, David ^a,b  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b Div of Hd and Neck Cancer Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; MICROSATELLITE DNA;

ALLELE; ARTICLE; CARCINOGENESIS; CHROMOSOME 3P; CHROMOSOME 9P; CHROMOSOME DELETION X; CHROMOSOME LOSS; CHROMOSOME SATELLITE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE LOCUS; HEAD AND NECK TUMOR; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; MALIGNANT TRANSFORMATION; MULTIPLE CANCER; PRIORITY JOURNAL; X CHROMOSOME INACTIVATION;

CHROMOSOMES, HUMAN, PAIR 3; CHROMOSOMES, HUMAN, PAIR 9; CLONE CELLS; DNA, NEOPLASM; DOSAGE COMPENSATION, GENETIC; FEMALE; GENETIC MARKERS; HEAD AND NECK NEOPLASMS; HETEROZYGOTE; HUMANS; MICROSATELLITE REPEATS; NEOPLASMS, MULTIPLE PRIMARY; SEQUENCE DELETION;

EID: 0029892745     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Slaughter, D. P , Southwick, H. W., and Smejkal, W "Field cancerization" in oral stratified squamous epithelium. Cancer, 6: 963-968, 1953.
2. Berg, J. W., Schottenfeld, D., and Ritter, F Incidence of multiple primary cancers. III. Cancers of the respiratory and upper digestive system as multiple primary cancers. J. Natl. Cancer Inst., 44. 263-270, 1970.
3. Licciardello, J T. W., Spitz, M. R., and Hong, W. K. Multiple primary cancer in patients with cancer of the head and neck: second cancer of the head and neck, esophagus, and lung. Int. J. Radiat Oncol Biol. Phys., 17: 467-476, 1989.
4. Chung, K Y , Mukopadhyay, T., Kim, J , Casson, A., Ro, J. Y., Goepfert, H., Hong, W. K., and Roth, J A. Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract. Cancer Res., 53: 1676-1683, 1993.
5. Sidransky, D , Frost, P., Von Eschenbach, A., Oyasu, R., Preisinger, A , and Vogelstein, B Clonal origin of bladder cancer New Engl. J. Med., 326. 737-740, 1992.
6. Worsham, M. J., Wolman, S. R., Carey, T E , Zarbo, R. J., Benninger, M. S., and Van Dyke, D. L. Common clonal origin of synchronous primary head and neck squamous cell carcinomas: analysis by tumor karyotypes and fluorescence in situ hybridization Hum Pathol , 26: 251-261, 1995.
7. Nawroz, H. van der Riet, P , Hruban, R H., Koch, W., Ruppert, J M., and Sidransky, D. Allelotype of head and neck squamous cell carcinoma. Cancer Res , 54. 1152-1155, 1994.
8. Wu, C. L., Sloan, P., Read, A. P., Harris, R., and Thakker, N. Deletion mapping on the short arm of chromosome 3 in squamous cell carcinoma of the oral cavity. Cancer Res., 54: 6484-6488, 1994.
9. Maestro, R., Gasparotto, D., Vukosavljevic, T., Luigi, B , Sulfaro, S., and Boiocchi, M. Three discrete regions of deletion in head and neck cancers. Cancer Res., 53: 5775-5779, 1993.
10. van der Riet, P., Karp, D., Farmer, E., Wei, Q., Grossman, L., Tokino, K., Ruppert, J. M., and Sidransky, D. Progression of basal cell carcinoma through loss of chromosome 9q and inactivation of a single p53 allele. Cancer Res., 54: 25-27, 1994
11. Rabkin, C. S , Bedi, G. C., Musaba, E., Sunkutu, R., Mwansa, N., Sidransky, D., and Biggar, R. J. AIDS-related Kaposi's sarcoma is a clonal neoplasm. Clin Cancer Res. J. 257-260, 1995.
12. Cairns, P., Polascik, T. J., Eby, Y., Tokino, K., Califano, J , Merlo, A , Mao, L., Herath, J., Jenkins, R. Westra, W , Rutter, J L , Buckler, A., Gabrielson, E., Tockman, M , Cho, K. R , Hedrick, L , Bova, G. S., Isaacs, W., Koch, W., Schwab, D., and Sidransky, D. Frequency of homozygous deletion at p16/CDKN2 in primary human tumors. Nat. Genet., 11: 210-212, 1995.
13. Lyons, M. F. Genetic evolution of the X-chromosome Nature (Lond.), 348. 585-586, 1990.
14. Mashal, R. D., Lester, S. C., and Sklar, J. Clonal analysis by study of X-chromosome inactivation in formalin-fixed paraffin-embedded tissue. Cancer Res., 53. 4676-4679, 1993.
15. Vogelstein, B., Fearon, E. R., Hamilton, S R., and Feinberg, A. P. Use of restriction fragment length polymorphisms to determine the clonal origin of human tumors. Science (Washington DC), 227: 645-648, 1985.
16. Gluckman, J. L., and Crissman, J. D. Survival rates in 548 patients with multiple neoplasms of the upper aerodigestive tract. Laryngoscope, 93: 71-74, 1983.
17. Cooper, J. S., Pajak, T. F., Rubin, P., Tupchong, L., Brady, L. W., Leibel, S A., Laramore, G. E., Marcial, V. A., Davis, L. W., and Cox, J. D. Second malignancies in patients who have head and neck cancer incidence, effect on survival and implications based on the ROTG experience. Int. J. Radiat. Oncol. Biol. Phys., 17: 449-456, 1989.
18. Fialkow, P. J. Clonal origin of human tumors. Biochim. Biophys. Acta, 458: 283-321, 1976.
19. Nowell, P. C. The clonal evolution of tumor cell populations. Science (Washington DC), 94: 23-28, 1976.
20. Bishop, J. M. The molecular genetics of cancer. Science (Washington DC), 235: 305-311, 1987.
21. Fearon, E. R. and Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell, 61: 759-767, 1990.
22. Sidransky, D., Mikkelsen, T., Schwechheimer, K., Rosenblum, M. L , Cavanee, W., and Vogelstein, B Clonal expansion of p53 mutant cells is associated with brain tumor progression. Nature (Lond.), 355: 846-847, 1992
23. Patel, V., Yeudall, W. A., Gardner, A., Mutlu, S., Scully, C., and Prime, S. S. Consistent chromosomal anomalies in keratinocyte cell lines derived from untreated malignant lesions of the oral cavity. Genes Chromosomes & Cancer, 7. 109-115, 1993.
24. Van Dyke, D. L., Worsham, M. J., Benninger, M. S , Krause, C J., Baker, S. R., Wolf, G. T , Drumheller, T , Tilley, B. C , and Carey, T. E. Recurrent cytogenetic abnormalities in squamous cell carcinomas of the head and neck region. Genes Chromosomes & Cancer, 9: 192-206, 1994.
25. Kamb, A., Gruis, N. A., Weaver-Feldhaus, J., Liu, Q., Harshman, K , Tavtigian, S. V., Stockert, E., Day III, R. S., Johnson, B E., and Skolnick, M. H A cell cycle regulator potentially involved in genesis of many tumor types. Science (Washington DC), 264: 436-440, 1994.
26. Nobori, T., Miura, K., Wu, D. J., Lois, A., Takabayashi, K., and Carson, D. A. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (Lond), 368: 753-756, 1994
27. Califano, J., van der Riet, P , Clayman, G., Westra, W., Piantadosi, S , Corio, R., Lee, D. J., Greenberg, B., Koch, W., and Sidransky, D. A genetic progression model for head and neck cancer; implications for field cancerization. Cancer Res., 56: 2488-2492, 1996.
28. Wooster, R., Cleton-Jansen, A.-M., Collins, N., Mangion, J., Cornelis, R. S., Cooper, C. S., Gusterson, B. A., Ponder, B. A. J., von Deimling, A., Wiestler, O. D., Cornelisse, C. J , Devilee, P., and Stratton, M. R. Instability of short tandem repeats (microsatellites) in human cancers. Nat. Genet., 6: 152-156, 1994.
29. Mao, L., Lee, D. J., Tockman, M. S., Erozan, Y. S., Askin, F., and Sidransky, D. Microsatellite alterations as clonal markers for the detection of human cancer. Proc. Natl. Acad. Sci. USA, 91: 9871-9875, 1994