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Volumn 3, Issue 12, 2007, Pages 2532-2545

Animal cell differentiation patterns suppress somatic evolution

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; HISTOLOGY; POPULATION STATISTICS; STEM CELLS;

EID: 37849017984     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.0030250     Document Type: Article
Times cited : (62)

References (81)
  • 1
    • 0031972059 scopus 로고    scopus 로고
    • Epigenetic inheritance in evolution
    • Jablonka E, Lamb MJ (1998) Epigenetic inheritance in evolution. J Evol Biol 11: 159-183.
    • (1998) J Evol Biol , vol.11 , pp. 159-183
    • Jablonka, E.1    Lamb, M.J.2
  • 2
    • 2342510386 scopus 로고    scopus 로고
    • Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
    • Dor Y, Brown J, Martinez OI, Melton DA (2004) Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429: 41-46.
    • (2004) Nature , vol.429 , pp. 41-46
    • Dor, Y.1    Brown, J.2    Martinez, O.I.3    Melton, D.A.4
  • 4
    • 0018575901 scopus 로고
    • A comparison of cell replacement in bone marrow, testis and three regions of surface epithelium
    • Potten CS, Schofield R, Lajtha LG (1979) A comparison of cell replacement in bone marrow, testis and three regions of surface epithelium. Biochimica et Biophysica Acta 560: 281-299.
    • (1979) Biochimica et Biophysica Acta , vol.560 , pp. 281-299
    • Potten, C.S.1    Schofield, R.2    Lajtha, L.G.3
  • 5
    • 0034614379 scopus 로고    scopus 로고
    • Stem cells: A new lease on life
    • Fuchs E, Segre JA (2000) Stem cells: A new lease on life. Cell 100: 143-155.
    • (2000) Cell , vol.100 , pp. 143-155
    • Fuchs, E.1    Segre, J.A.2
  • 6
    • 0032578019 scopus 로고    scopus 로고
    • Stem cells in gastrointestinal epithelium: Numbers, characteristics and death
    • Potten CS (1998) Stem cells in gastrointestinal epithelium: Numbers, characteristics and death. Philos Trans R Soc Lond B Biol Sci 353: 821-830.
    • (1998) Philos Trans R Soc Lond B Biol Sci , vol.353 , pp. 821-830
    • Potten, C.S.1
  • 7
    • 0034014936 scopus 로고    scopus 로고
    • Epithelial stem cell repertoire in the gut: Clues to the origin of cell lineages, proliferative units and cancer
    • Wright NA (2000) Epithelial stem cell repertoire in the gut: Clues to the origin of cell lineages, proliferative units and cancer. Int J Exp Pathol 81: 117-143.
    • (2000) Int J Exp Pathol , vol.81 , pp. 117-143
    • Wright, N.A.1
  • 8
    • 0032577990 scopus 로고    scopus 로고
    • Epidermal stem cells: Markers, patterning and the control of stem cell fate
    • Watt FM (1998) Epidermal stem cells: Markers, patterning and the control of stem cell fate. Philos Trans R Soc Lond B Biol Sci 353: 831-837.
    • (1998) Philos Trans R Soc Lond B Biol Sci , vol.353 , pp. 831-837
    • Watt, F.M.1
  • 9
    • 33846833986 scopus 로고    scopus 로고
    • The morphogenetic code and colon cancer development
    • van den Brink GR, Offerhaus GJ (2007) The morphogenetic code and colon cancer development. Cancer Cell 11: 109-117.
    • (2007) Cancer Cell , vol.11 , pp. 109-117
    • van den Brink, G.R.1    Offerhaus, G.J.2
  • 10
    • 34249315487 scopus 로고    scopus 로고
    • Morphogens, morphostats, microarchitecture and malignancy
    • Potter JD (2007) Morphogens, morphostats, microarchitecture and malignancy. Nat Rev Cancer 7: 464-474.
    • (2007) Nat Rev Cancer , vol.7 , pp. 464-474
    • Potter, J.D.1
  • 11
    • 33847237571 scopus 로고    scopus 로고
    • Darwinian medicine: A case for cancer
    • Greaves M (2007) Darwinian medicine: A case for cancer. Nat Rev Cancer 7: 213-221.
    • (2007) Nat Rev Cancer , vol.7 , pp. 213-221
    • Greaves, M.1
  • 12
    • 24944468183 scopus 로고    scopus 로고
    • Evolutionary biology of cancer
    • Crespi B, Summers K (2005) Evolutionary biology of cancer. Trends Ecol Evol 20: 545-552.
    • (2005) Trends Ecol Evol , vol.20 , pp. 545-552
    • Crespi, B.1    Summers, K.2
  • 13
    • 33746255375 scopus 로고    scopus 로고
    • Positive selection in the evolution of cancer
    • Crespi BJ, Summers K (2006) Positive selection in the evolution of cancer. Biol Rev Camb Philos Soc 81: 407-424.
    • (2006) Biol Rev Camb Philos Soc , vol.81 , pp. 407-424
    • Crespi, B.J.1    Summers, K.2
  • 15
    • 0004236135 scopus 로고
    • Princeton New Jersey, Princeton University Press. 201 p
    • Buss LW (1987) The evolution of individuality. Princeton (New Jersey): Princeton University Press. 201 p.
    • (1987) The evolution of individuality
    • Buss, L.W.1
  • 17
    • 0030619987 scopus 로고    scopus 로고
    • Cooperation and conflict in the evolution of individuality. I. Multilevel selection of the organism
    • Michod RE (1997) Cooperation and conflict in the evolution of individuality. I. Multilevel selection of the organism. Am Nat 149: 607-645.
    • (1997) Am Nat , vol.149 , pp. 607-645
    • Michod, R.E.1
  • 18
    • 0027938339 scopus 로고
    • Inheritance systems and the evolution of new levels of individuality
    • Jablonka E (1994) Inheritance systems and the evolution of new levels of individuality. J Theor Biol 170: 301-309.
    • (1994) J Theor Biol , vol.170 , pp. 301-309
    • Jablonka, E.1
  • 19
    • 0038650591 scopus 로고    scopus 로고
    • Embedded molecular switches, anticancer selection, and effects on ontogenetic rates: A hypothesis of developmental constraint on morphogenesis and evolution
    • Kavanagh KD (2003) Embedded molecular switches, anticancer selection, and effects on ontogenetic rates: A hypothesis of developmental constraint on morphogenesis and evolution. Evolution 57: 939-948.
    • (2003) Evolution , vol.57 , pp. 939-948
    • Kavanagh, K.D.1
  • 20
    • 0016692602 scopus 로고
    • Mutation selection and the natural history of cancer
    • Cairns J (1975) Mutation selection and the natural history of cancer. Nature 255: 197-200.
    • (1975) Nature , vol.255 , pp. 197-200
    • Cairns, J.1
  • 21
    • 0025773554 scopus 로고
    • Mutator phenotype may be required for multistage carcinogenesis
    • Loeb LA (1991) Mutator phenotype may be required for multistage carcinogenesis. Cancer Res 51: 3075-3079.
    • (1991) Cancer Res , vol.51 , pp. 3075-3079
    • Loeb, L.A.1
  • 22
    • 33748882013 scopus 로고    scopus 로고
    • Characterization of epithelial cell shedding from human small intestine
    • Bullen TF, Forrest S, Campbell F, Dodson AR, Hershman MJ, et al. (2006) Characterization of epithelial cell shedding from human small intestine. Lab Invest 86: 1052-1063.
    • (2006) Lab Invest , vol.86 , pp. 1052-1063
    • Bullen, T.F.1    Forrest, S.2    Campbell, F.3    Dodson, A.R.4    Hershman, M.J.5
  • 23
    • 37849014167 scopus 로고    scopus 로고
    • Jandl JH (1996) Blood. Boston: Little, Brown and Co. 1214 p.
    • Jandl JH (1996) Blood. Boston: Little, Brown and Co. 1214 p.
  • 25
    • 32644466811 scopus 로고    scopus 로고
    • Endogenous parasitism: A biological process with implications for senescence
    • Charlton BG (1996) Endogenous parasitism: A biological process with implications for senescence. Evolutionary Theory 11: 119-124.
    • (1996) Evolutionary Theory , vol.11 , pp. 119-124
    • Charlton, B.G.1
  • 27
    • 34047194073 scopus 로고    scopus 로고
    • Dingli D, Traulsen A, Michor F (2007) (A)symmetric stem cell replication and cancer. PLoS Comput Biol 3: e53.
    • Dingli D, Traulsen A, Michor F (2007) (A)symmetric stem cell replication and cancer. PLoS Comput Biol 3: e53.
  • 28
    • 0028803770 scopus 로고
    • Failure of programmed cell death and differentiation as causes of tumors: Some simple mathematical models
    • Tomlinson IPM, Bodmer WF (1995) Failure of programmed cell death and differentiation as causes of tumors: Some simple mathematical models. Proc Natl Acad Sci U S A 92: 11130-11134.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 11130-11134
    • Tomlinson, I.P.M.1    Bodmer, W.F.2
  • 29
    • 0034731032 scopus 로고    scopus 로고
    • Relatedness and the fraternal major transitions
    • Queller DC (2000) Relatedness and the fraternal major transitions. Philos Trans R Soc Lond B Biol Sci 355: 1647-1655.
    • (2000) Philos Trans R Soc Lond B Biol Sci , vol.355 , pp. 1647-1655
    • Queller, D.C.1
  • 31
    • 33846292197 scopus 로고    scopus 로고
    • Evolved for cancer?
    • Zimmer C (2007) Evolved for cancer? Sci Am 296: 68-74, 75A.
    • (2007) Sci Am , vol.296 , Issue.68-74
    • Zimmer, C.1
  • 32
    • 0031877999 scopus 로고    scopus 로고
    • The Role of DNA in invertebrates: Developmental regulation or genome defense?
    • Regev A, Lamb MJ, Jablonka E (1998) The Role of DNA in invertebrates: Developmental regulation or genome defense? Mol Biol Evol 15: 880-891.
    • (1998) Mol Biol Evol , vol.15 , pp. 880-891
    • Regev, A.1    Lamb, M.J.2    Jablonka, E.3
  • 33
    • 29244469466 scopus 로고    scopus 로고
    • The epigenetic progenitor origin of human cancer
    • Feinberg AP, Ohlsson R, Henikoff S (2006) The epigenetic progenitor origin of human cancer. Nat Rev Genet 7: 21-33.
    • (2006) Nat Rev Genet , vol.7 , pp. 21-33
    • Feinberg, A.P.1    Ohlsson, R.2    Henikoff, S.3
  • 34
    • 31744433660 scopus 로고    scopus 로고
    • Evidence for an instructive mechanism of de novo methylation in cancer cells
    • Keshet I, Schlesinger Y, Farkash S, Rand E, Hecht M, et al. (2006) Evidence for an instructive mechanism of de novo methylation in cancer cells. Nat Genet 38: 149-153.
    • (2006) Nat Genet , vol.38 , pp. 149-153
    • Keshet, I.1    Schlesinger, Y.2    Farkash, S.3    Rand, E.4    Hecht, M.5
  • 35
    • 33745541234 scopus 로고    scopus 로고
    • CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
    • Weisenberger DJ, Siegmund KD, Campan M, Young J, Long TI, et al. (2006) CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 38: 787-793.
    • (2006) Nat Genet , vol.38 , pp. 787-793
    • Weisenberger, D.J.1    Siegmund, K.D.2    Campan, M.3    Young, J.4    Long, T.I.5
  • 37
    • 2442649306 scopus 로고    scopus 로고
    • Selectively advantageous mutations and hitchhikers in neoplasms: P16 lesions are selected in Barrett's esophagus
    • Maley CC, Galipeau PC, Li X, Sanchez CA, Paulson TG, et al. (2004) Selectively advantageous mutations and hitchhikers in neoplasms: p16 lesions are selected in Barrett's esophagus. Cancer Res 64: 3414-3427.
    • (2004) Cancer Res , vol.64 , pp. 3414-3427
    • Maley, C.C.1    Galipeau, P.C.2    Li, X.3    Sanchez, C.A.4    Paulson, T.G.5
  • 38
    • 0034614576 scopus 로고    scopus 로고
    • Stem cells: Units of development, units of regeneration, and units in evolution
    • Weissman IL (2000) Stem cells: Units of development, units of regeneration, and units in evolution. Cell 100: 157-168.
    • (2000) Cell , vol.100 , pp. 157-168
    • Weissman, I.L.1
  • 39
    • 33750126450 scopus 로고    scopus 로고
    • Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment
    • McKenzie JL, Gan OI, Doedens M, Wang JC, Dick JE (2006) Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment. Nat Immunol 7: 1225-1233.
    • (2006) Nat Immunol , vol.7 , pp. 1225-1233
    • McKenzie, J.L.1    Gan, O.I.2    Doedens, M.3    Wang, J.C.4    Dick, J.E.5
  • 40
    • 18644376279 scopus 로고    scopus 로고
    • Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB
    • Batlle E, Henderson JT, Beghtel H, van den Born MM, Sancho E, et al. (2002) Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell 111: 251-263.
    • (2002) Cell , vol.111 , pp. 251-263
    • Batlle, E.1    Henderson, J.T.2    Beghtel, H.3    van den Born, M.M.4    Sancho, E.5
  • 43
    • 34547132777 scopus 로고    scopus 로고
    • Immunosenescence: Deficits in adaptive immunity in the elderly
    • Hakim FT, Gress RE (2007) Immunosenescence: Deficits in adaptive immunity in the elderly. Tissue Antigens 70: 179-189.
    • (2007) Tissue Antigens , vol.70 , pp. 179-189
    • Hakim, F.T.1    Gress, R.E.2
  • 45
    • 0242416667 scopus 로고    scopus 로고
    • Cell biology: Developmental predisposition to cancer
    • Frank SA, Nowak MA (2003) Cell biology: Developmental predisposition to cancer. Nature 422: 494.
    • (2003) Nature , vol.422 , pp. 494
    • Frank, S.A.1    Nowak, M.A.2
  • 47
    • 0015319601 scopus 로고
    • The Hutchinson-Gilford progeria syndrome. Report of 4 cases and review of the literature
    • DeBusk FL (1972) The Hutchinson-Gilford progeria syndrome. Report of 4 cases and review of the literature. J Pediatr 80: 697-724.
    • (1972) J Pediatr , vol.80 , pp. 697-724
    • DeBusk, F.L.1
  • 49
    • 4243340662 scopus 로고    scopus 로고
    • Breast cancer in evolutionary context
    • Trevathan WR, Smith EO, McKenna JJ, editors, Oxford United Kingdom, Oxford University Press. pp
    • Eaton SB, Eaton SB (1999) Breast cancer in evolutionary context. In: Trevathan WR, Smith EO, McKenna JJ, editors. Evolutionary Medicine. Oxford (United Kingdom): Oxford University Press. pp. 429-442.
    • (1999) Evolutionary Medicine , pp. 429-442
    • Eaton, S.B.1    Eaton, S.B.2
  • 51
    • 0029816023 scopus 로고    scopus 로고
    • The use of a computer model to simulate epithelial pathologies
    • Rashbass J, Stekel D, Williams ED (1996) The use of a computer model to simulate epithelial pathologies. J Pathol 179: 333-339.
    • (1996) J Pathol , vol.179 , pp. 333-339
    • Rashbass, J.1    Stekel, D.2    Williams, E.D.3
  • 54
    • 0030932869 scopus 로고    scopus 로고
    • Cancer-susceptibility genes. Gatekeepers and caretakers
    • Kinzler KW, Vogelstein B (1997) Cancer-susceptibility genes. Gatekeepers and caretakers. Nature 386: 761, 763.
    • (1997) Nature , vol.386 , Issue.761 , pp. 763
    • Kinzler, K.W.1    Vogelstein, B.2
  • 55
    • 34147224008 scopus 로고    scopus 로고
    • Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
    • Mullighan CG, Goorha S, Radtke I, Miller CB, Coustan-Smith E, et al. (2007) Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature 446: 758-764.
    • (2007) Nature , vol.446 , pp. 758-764
    • Mullighan, C.G.1    Goorha, S.2    Radtke, I.3    Miller, C.B.4    Coustan-Smith, E.5
  • 56
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 58
    • 0032555418 scopus 로고    scopus 로고
    • Control of cell proliferation by progress in differentiation: Clues to mechanisms of aging, cancer causation and therapy
    • von Wangenheim KH, Peterson HP (1998) Control of cell proliferation by progress in differentiation: Clues to mechanisms of aging, cancer causation and therapy. J Theor Biol 193: 663-678.
    • (1998) J Theor Biol , vol.193 , pp. 663-678
    • von Wangenheim, K.H.1    Peterson, H.P.2
  • 60
    • 0028228920 scopus 로고
    • The DCC gene product in cellular differentiation and colorectal tumorigenesis
    • Hedrick L, Cho KR, Fearon ER, Wu TC, Kinzler KW, et al. (1994) The DCC gene product in cellular differentiation and colorectal tumorigenesis. Genes Dev 8: 1174-1183.
    • (1994) Genes Dev , vol.8 , pp. 1174-1183
    • Hedrick, L.1    Cho, K.R.2    Fearon, E.R.3    Wu, T.C.4    Kinzler, K.W.5
  • 61
    • 0031581653 scopus 로고    scopus 로고
    • Hierarchical organization of biological systems and the structure of adaptation in evolution and tumorigenesis
    • Nederbragt H (1997) Hierarchical organization of biological systems and the structure of adaptation in evolution and tumorigenesis. J Theor Biol 184: 149-156.
    • (1997) J Theor Biol , vol.184 , pp. 149-156
    • Nederbragt, H.1
  • 62
    • 0034610272 scopus 로고    scopus 로고
    • Epidermal stem cells: Properties, markers, and location
    • Lavker RM, Sun TT (2000) Epidermal stem cells: Properties, markers, and location. Proc Natl Acad Sci U S A 97: 13473-13475.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 13473-13475
    • Lavker, R.M.1    Sun, T.T.2
  • 64
    • 0029688325 scopus 로고    scopus 로고
    • Senescence, cancer and 'endogenous parasites': A salutogenic hypothesis
    • Charlton BG (1996) Senescence, cancer and 'endogenous parasites': A salutogenic hypothesis. J R Coll Physicians Lond 30: 10-12.
    • (1996) J R Coll Physicians Lond , vol.30 , pp. 10-12
    • Charlton, B.G.1
  • 65
    • 0036792092 scopus 로고    scopus 로고
    • Metapopulation dynamics and spatial heterogeneity in cancer
    • Gonzalez-Garcia I, Sole RV, Costa J (2002) Metapopulation dynamics and spatial heterogeneity in cancer. Proc Natl Acad Sci U S A 99: 13085-13089.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13085-13089
    • Gonzalez-Garcia, I.1    Sole, R.V.2    Costa, J.3
  • 66
    • 33748040769 scopus 로고    scopus 로고
    • Spencer SL, Gerety RA, Pienta KJ, Forrest S (2006) Modeling somatic evolution in tumorigenesis. PLoS Comput Biol 2: e108.
    • Spencer SL, Gerety RA, Pienta KJ, Forrest S (2006) Modeling somatic evolution in tumorigenesis. PLoS Comput Biol 2: e108.
  • 67
    • 0034278890 scopus 로고    scopus 로고
    • Exploring the relationship between neutral and selective mutations in cancer
    • Maley CC, Forrest S (2000) Exploring the relationship between neutral and selective mutations in cancer. Artificial Life 6: 325-345.
    • (2000) Artificial Life , vol.6 , pp. 325-345
    • Maley, C.C.1    Forrest, S.2
  • 68
    • 4043075127 scopus 로고    scopus 로고
    • Cancer prevention strategies that address the evolutionary dynamics of neoplastic cells: Simulating benign cell boosters and selection for chemosensitivity
    • Maley CC, Reid BJ, Forrest S (2004) Cancer prevention strategies that address the evolutionary dynamics of neoplastic cells: Simulating benign cell boosters and selection for chemosensitivity. Cancer Epidemiol Biomarkers Prev 13: 1375-1384.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 1375-1384
    • Maley, C.C.1    Reid, B.J.2    Forrest, S.3
  • 69
    • 0031081389 scopus 로고    scopus 로고
    • Modeling signal transduction in normal and cancer cells using complex adaptive systems
    • Schwab ED, Pienta KJ (1997) Modeling signal transduction in normal and cancer cells using complex adaptive systems. Med Hypotheses 48: 111-123.
    • (1997) Med Hypotheses , vol.48 , pp. 111-123
    • Schwab, E.D.1    Pienta, K.J.2
  • 70
  • 71
    • 2942585152 scopus 로고    scopus 로고
    • A phase space model of hemopoiesis and the concept of stem cell renewal
    • Kirkland MA (2004) A phase space model of hemopoiesis and the concept of stem cell renewal. Exp Hematol 32: 511-519.
    • (2004) Exp Hematol , vol.32 , pp. 511-519
    • Kirkland, M.A.1
  • 72
    • 37849041710 scopus 로고    scopus 로고
    • Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche
    • Arai F, Suda T (2007) Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche. Ann N Y Acad Sci 602: 61-67.
    • (2007) Ann N Y Acad Sci , vol.602 , pp. 61-67
    • Arai, F.1    Suda, T.2
  • 73
    • 0037396610 scopus 로고    scopus 로고
    • Patterns of cell division and the risk of cancer
    • Frank SA, Iwasa Y, Nowak MA (2003) Patterns of cell division and the risk of cancer. Genetics 163: 1527-1532.
    • (2003) Genetics , vol.163 , pp. 1527-1532
    • Frank, S.A.1    Iwasa, Y.2    Nowak, M.A.3
  • 74
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell PC (1976) The clonal evolution of tumor cell populations. Science 194: 23-28.
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 75
    • 0030830309 scopus 로고    scopus 로고
    • The cellular basis of tumor progression
    • Heppner G, Miller F (1998) The cellular basis of tumor progression. Int Rev Cytol 177: 1-56.
    • (1998) Int Rev Cytol , vol.177 , pp. 1-56
    • Heppner, G.1    Miller, F.2
  • 76
    • 0029795904 scopus 로고    scopus 로고
    • Cancer as a complex adaptive system
    • Schwab ED, Pienta KJ (1996) Cancer as a complex adaptive system. Med Hypotheses 47: 235-241.
    • (1996) Med Hypotheses , vol.47 , pp. 235-241
    • Schwab, E.D.1    Pienta, K.J.2
  • 77
    • 4243167848 scopus 로고    scopus 로고
    • How are the sizes of cells, organs, and bodies controlled?
    • Hafen E, Stocker H (2003) How are the sizes of cells, organs, and bodies controlled? PLoS Biol 1: E86.
    • (2003) PLoS Biol , vol.1
    • Hafen, E.1    Stocker, H.2
  • 78
    • 0037227316 scopus 로고    scopus 로고
    • Erythropoietin: Physiology and pharmacology update
    • Fisher JW (2003) Erythropoietin: Physiology and pharmacology update. Exp Biol Med (Maywood) 228: 1-14.
    • (2003) Exp Biol Med (Maywood) , vol.228 , pp. 1-14
    • Fisher, J.W.1
  • 79
    • 33745600820 scopus 로고    scopus 로고
    • Asymmetric and symmetric stem-cell divisions in development and cancer
    • Morrison SJ, Kimble J (2006) Asymmetric and symmetric stem-cell divisions in development and cancer. Nature 441: 1068-1074.
    • (2006) Nature , vol.441 , pp. 1068-1074
    • Morrison, S.J.1    Kimble, J.2
  • 80
    • 0034080251 scopus 로고    scopus 로고
    • Gut instincts: Thoughts on intestinal epithelial stem cells
    • Booth C, Potten CS (2000) Gut instincts: Thoughts on intestinal epithelial stem cells. J Clin Invest 105: 1493-1499.
    • (2000) J Clin Invest , vol.105 , pp. 1493-1499
    • Booth, C.1    Potten, C.S.2
  • 81
    • 0037068376 scopus 로고    scopus 로고
    • Methylation reveals a niche: Stem cell succession in human colon crypts
    • Kim KM, Shibata D (2002) Methylation reveals a niche: Stem cell succession in human colon crypts. Oncogene 21: 5441-5449.
    • (2002) Oncogene , vol.21 , pp. 5441-5449
    • Kim, K.M.1    Shibata, D.2


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