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Volumn 6, Issue 1, 2007, Pages 44-51

Polyclonal tumors in the mammalian intestine: Are interactions among multiple initiated clones necessary for tumor initiation, growth, and progression?

Author keywords

And EgfR; Apc; Cox 2; Crypt purification; Intestinal cancer; Polyclonal structure; Random collision; Short range interactions

Indexed keywords

CARCINOGENESIS; CELL INTERACTION; CELL TRANSFORMATION; CLONAL VARIATION; COLORECTAL TUMOR; HUMAN; INTESTINE TUMOR; MOSAICISM; NONHUMAN; REGULATORY MECHANISM; REVIEW; TUMOR GROWTH;

EID: 33846614926     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.6.1.3651     Document Type: Review
Times cited : (15)

References (65)
  • 1
    • 23344448317 scopus 로고    scopus 로고
    • American Cancer Society, Special Edition
    • American Cancer Society. Colorectal Cancer Facts and Figures Special Edition 2005.
    • (2005) Colorectal Cancer Facts and Figures
  • 2
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996; 87:159-70.
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 6
    • 0023780022 scopus 로고
    • Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine
    • Schmidt GH, Winton DJ, Ponder BAJ. Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine. Development 1988; 103:785-90.
    • (1988) Development , vol.103 , pp. 785-790
    • Schmidt, G.H.1    Winton, D.J.2    Ponder, B.A.J.3
  • 7
    • 0016692602 scopus 로고
    • Mutation selection and the natural history of cancer
    • Cairns J. Mutation selection and the natural history of cancer. Nature 1975; 255:197-200.
    • (1975) Nature , vol.255 , pp. 197-200
    • Cairns, J.1
  • 8
    • 0027196626 scopus 로고
    • Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas
    • Shibata D, Schaeffer J, Li ZH, Capella G, Perucho M. Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas. J Natl Cancer Inst 1993; 85:1058-63.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1058-1063
    • Shibata, D.1    Schaeffer, J.2    Li, Z.H.3    Capella, G.4    Perucho, M.5
  • 13
    • 0023301321 scopus 로고
    • Familial polyposis coli
    • Bulow S. Familial polyposis coli. Dan Med Bull 1987; 34:1-15.
    • (1987) Dan Med Bull , vol.34 , pp. 1-15
    • Bulow, S.1
  • 15
    • 0022977531 scopus 로고
    • Hereditary gastrointestinal polyposis syndromes
    • Haggitt RC, Reid BJ. Hereditary gastrointestinal polyposis syndromes. Am J Surg Pathol 1986; 10:871-87.
    • (1986) Am J Surg Pathol , vol.10 , pp. 871-887
    • Haggitt, R.C.1    Reid, B.J.2
  • 16
    • 0031557898 scopus 로고    scopus 로고
    • The adenomatous polyposis coli (APC) tumor suppressor
    • Polakis P. The adenomatous polyposis coli (APC) tumor suppressor. Biochim Biophys Acta 1997; 1332:F127-F148.
    • (1997) Biochim Biophys Acta , vol.1332
    • Polakis, P.1
  • 17
    • 0031718204 scopus 로고    scopus 로고
    • Differential molecular interactions of β-catenin and plakoglobin in adhesion, signaling and cancer
    • Ben Ze'ev A, Geiger B. Differential molecular interactions of β-catenin and plakoglobin in adhesion, signaling and cancer. Curr Opin Cell Biol 1998; 10:629-39.
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 629-639
    • Ben Ze'ev, A.1    Geiger, B.2
  • 18
    • 0032585647 scopus 로고    scopus 로고
    • EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle
    • Morrison EE, Wardleworth BN, Askham JM, Markham AF, Meredith DM. EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle. Oncogene 1998; 17:3471-7.
    • (1998) Oncogene , vol.17 , pp. 3471-3477
    • Morrison, E.E.1    Wardleworth, B.N.2    Askham, J.M.3    Markham, A.F.4    Meredith, D.M.5
  • 19
    • 0023261211 scopus 로고
    • Clonal analysis of human colorectal tumors
    • Fearon ER, Hamilton SR, Vogelstein B. Clonal analysis of human colorectal tumors. Science 1987; 238:193-7.
    • (1987) Science , vol.238 , pp. 193-197
    • Fearon, E.R.1    Hamilton, S.R.2    Vogelstein, B.3
  • 20
    • 0014208048 scopus 로고
    • Value of genetic variants of glucose-6-phosphate dehydrogenase in tracing the origin of malignant tumors
    • Beutler E, Collins Z, Irwin LE. Value of genetic variants of glucose-6-phosphate dehydrogenase in tracing the origin of malignant tumors. N Engl J Med 1967; 276:389-91.
    • (1967) N Engl J Med , vol.276 , pp. 389-391
    • Beutler, E.1    Collins, Z.2    Irwin, L.E.3
  • 25
    • 33748786777 scopus 로고    scopus 로고
    • A statistical test of the hypothesis that polyclonal intestinal tumors arise by the random collision of initiated clones
    • Newton MA, Clipson L, Thliveris AT, Halberg RB. A statistical test of the hypothesis that polyclonal intestinal tumors arise by the random collision of initiated clones. Biometrics 2006; 62:721-7.
    • (2006) Biometrics , vol.62 , pp. 721-727
    • Newton, M.A.1    Clipson, L.2    Thliveris, A.T.3    Halberg, R.B.4
  • 26
    • 33749604277 scopus 로고    scopus 로고
    • On estimating the polyclonal fraction in lineage-marker studies of tumor origin
    • Newton MA. On estimating the polyclonal fraction in lineage-marker studies of tumor origin. Biostatistics 2006; 7:503-14.
    • (2006) Biostatistics , vol.7 , pp. 503-514
    • Newton, M.A.1
  • 27
    • 2442694111 scopus 로고    scopus 로고
    • Tracing ancestry with methylation patterns: Most crypts appear distantly related in normal adult human colon
    • Kim KM, Shibata D. Tracing ancestry with methylation patterns: Most crypts appear distantly related in normal adult human colon. BMC Gastroenterol 2004; 4:8.
    • (2004) BMC Gastroenterol , vol.4 , pp. 8
    • Kim, K.M.1    Shibata, D.2
  • 29
    • 22444444402 scopus 로고    scopus 로고
    • Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse
    • Collier LS, Carlson CM, Ravimohan S, Dupuy AJ, Largaespada DA. Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse. Nature 2005; 436:272-6.
    • (2005) Nature , vol.436 , pp. 272-276
    • Collier, L.S.1    Carlson, C.M.2    Ravimohan, S.3    Dupuy, A.J.4    Largaespada, D.A.5
  • 30
    • 0027230369 scopus 로고
    • Extrinsic factors in cellular differentiation
    • Gardner RL. Extrinsic factors in cellular differentiation. Int J Dev Biol 1993; 37:47-50.
    • (1993) Int J Dev Biol , vol.37 , pp. 47-50
    • Gardner, R.L.1
  • 31
    • 0027745771 scopus 로고
    • Community effects and related phenomena in development
    • Gurdon JB, Lemaire P, Kato K. Community effects and related phenomena in development. Cell 1993; 75:831-4.
    • (1993) Cell , vol.75 , pp. 831-834
    • Gurdon, J.B.1    Lemaire, P.2    Kato, K.3
  • 32
    • 0023239424 scopus 로고
    • Homeo boxes in the study of development
    • Gehring WJ. Homeo boxes in the study of development. Science 1987; 236:1245-52.
    • (1987) Science , vol.236 , pp. 1245-1252
    • Gehring, W.J.1
  • 33
    • 84970070866 scopus 로고
    • Conditional neoplasms and subthreshold neoplastic states
    • Rous P, Kidd JG. Conditional neoplasms and subthreshold neoplastic states. J Exp Med 1940; 73:365-95.
    • (1940) J Exp Med , vol.73 , pp. 365-395
    • Rous, P.1    Kidd, J.G.2
  • 34
    • 2342468135 scopus 로고    scopus 로고
    • 2/M cell cycle block in transformed cells by contact with normal neighbors
    • 2/M cell cycle block in transformed cells by contact with normal neighbors. Cell Cycle 2003; 2:484-7.
    • (2003) Cell Cycle , vol.2 , pp. 484-487
    • Allard, D.1    Stoker, M.2    Gherardi, E.3
  • 35
    • 28944432805 scopus 로고    scopus 로고
    • Hill R, Song Y, Cardiff RD, Van Dyke T. Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis. Cell 2005; 123:1001-11.
    • Hill R, Song Y, Cardiff RD, Van Dyke T. Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis. Cell 2005; 123:1001-11.
  • 36
    • 0030932869 scopus 로고    scopus 로고
    • Cancer-susceptibility genes. Gatekeepers and caretakers
    • Kinzler KW, Vogelstein B. Cancer-susceptibility genes. Gatekeepers and caretakers. Nature 1997; 386:761-763.
    • (1997) Nature , vol.386 , pp. 761-763
    • Kinzler, K.W.1    Vogelstein, B.2
  • 37
    • 23844537506 scopus 로고    scopus 로고
    • Studying the consequences of immediate loss of gene function in the intestine: APC
    • Clarke AR. Studying the consequences of immediate loss of gene function in the intestine: APC. Biochem Soc Trans 2005; 33:665-6.
    • (2005) Biochem Soc Trans , vol.33 , pp. 665-666
    • Clarke, A.R.1
  • 40
    • 0033028730 scopus 로고    scopus 로고
    • Colossal crypts bordering colon adenomas in Apc(Min) mice express full-length Apc
    • Bjerknes M, Cheng H. Colossal crypts bordering colon adenomas in Apc(Min) mice express full-length Apc. Am J Pathol 1999; 154:1831-4.
    • (1999) Am J Pathol , vol.154 , pp. 1831-1834
    • Bjerknes, M.1    Cheng, H.2
  • 41
    • 0037229064 scopus 로고    scopus 로고
    • Haigis KM, Dove WF. A Robertsonian translocation suppresses a somatic recombination pathway to loss of heterozygosity. Nat Genet 2003; 33:33-9.
    • Haigis KM, Dove WF. A Robertsonian translocation suppresses a somatic recombination pathway to loss of heterozygosity. Nat Genet 2003; 33:33-9.
  • 44
    • 13744254574 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and epidermal growth factor receptor: Pharmacologic targets for chemoprevention
    • Dannenberg AJ, Lippman SM, Mann JR, Subbaramaiah K, DuBois RN. Cyclooxygenase-2 and epidermal growth factor receptor: Pharmacologic targets for chemoprevention. J Clin Oncol 2005; 23:254-66.
    • (2005) J Clin Oncol , vol.23 , pp. 254-266
    • Dannenberg, A.J.1    Lippman, S.M.2    Mann, J.R.3    Subbaramaiah, K.4    DuBois, R.N.5
  • 45
    • 0346368096 scopus 로고    scopus 로고
    • Targeting cyclooxygenase-2 in human neoplasia: Rationale and promise
    • Dannenberg AJ, Subbaramaiah K. Targeting cyclooxygenase-2 in human neoplasia: Rationale and promise. Cancer Cell 2003; 4:431-6.
    • (2003) Cancer Cell , vol.4 , pp. 431-436
    • Dannenberg, A.J.1    Subbaramaiah, K.2
  • 48
    • 0041816104 scopus 로고    scopus 로고
    • Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor
    • Buchanan FG, Wing D, Bargiacchi F, DuBois RN. Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor. J Biol Chem 2003; 278:35451-7.
    • (2003) J Biol Chem , vol.278 , pp. 35451-35457
    • Buchanan, F.G.1    Wing, D.2    Bargiacchi, F.3    DuBois, R.N.4
  • 49
    • 0141593676 scopus 로고    scopus 로고
    • Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulin
    • Shao J, Lee SB, Guo H, Evers BM, Sheng H. Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulin. Cancer Res 2003; 63:5218-23.
    • (2003) Cancer Res , vol.63 , pp. 5218-5223
    • Shao, J.1    Lee, S.B.2    Guo, H.3    Evers, B.M.4    Sheng, H.5
  • 50
    • 0036006453 scopus 로고    scopus 로고
    • Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
    • Pai R, Soreghan B, Szabo IL, Pavelka M, Baatar D, Tarnawski AS. Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy. Nat Med 2002; 8:289-93.
    • (2002) Nat Med , vol.8 , pp. 289-293
    • Pai, R.1    Soreghan, B.2    Szabo, I.L.3    Pavelka, M.4    Baatar, D.5    Tarnawski, A.S.6
  • 52
    • 0032521401 scopus 로고    scopus 로고
    • Nonsmall cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: Up-regulation of interleukin 10 and down-regulation of interleukin 12 production
    • Huang M, Stolina M, Sharma S, Mao JT, Zhu L, Miller PW, Wollman J, Herschman H, Dubinett SM. Nonsmall cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: Up-regulation of interleukin 10 and down-regulation of interleukin 12 production. Cancer Res 1998; 58:1208-16.
    • (1998) Cancer Res , vol.58 , pp. 1208-1216
    • Huang, M.1    Stolina, M.2    Sharma, S.3    Mao, J.T.4    Zhu, L.5    Miller, P.W.6    Wollman, J.7    Herschman, H.8    Dubinett, S.M.9
  • 53
    • 0021288454 scopus 로고
    • Prostaglandin E2-mediated suppression of cellular immunity in colon cancer patients
    • Balch CM, Dougherty PA, Cloud GA, Tilden AB. Prostaglandin E2-mediated suppression of cellular immunity in colon cancer patients. Surgery 1984; 95:71-7.
    • (1984) Surgery , vol.95 , pp. 71-77
    • Balch, C.M.1    Dougherty, P.A.2    Cloud, G.A.3    Tilden, A.B.4
  • 54
    • 0021043226 scopus 로고
    • Regulation of the immune response by prostaglandins
    • Goodwin JS, Ceuppens J. Regulation of the immune response by prostaglandins. J Clin Immunol 1983; 3:295-315.
    • (1983) J Clin Immunol , vol.3 , pp. 295-315
    • Goodwin, J.S.1    Ceuppens, J.2
  • 55
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii M, DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995; 83:493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    DuBois, R.N.2
  • 57
    • 0031984810 scopus 로고    scopus 로고
    • Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells
    • Sheng H, Shao J, Morrow JD, Beauchamp RD, DuBois RN. Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res 1998; 58:362-6.
    • (1998) Cancer Res , vol.58 , pp. 362-366
    • Sheng, H.1    Shao, J.2    Morrow, J.D.3    Beauchamp, R.D.4    DuBois, R.N.5
  • 58
    • 0035947586 scopus 로고    scopus 로고
    • Prostaglandin E2 increases growth and motility of colorectal carcinoma cells
    • Sheng H, Shao J, Washington MK, DuBois RN. Prostaglandin E2 increases growth and motility of colorectal carcinoma cells. J Biol Chem 2001; 276:18075-81.
    • (2001) J Biol Chem , vol.276 , pp. 18075-18081
    • Sheng, H.1    Shao, J.2    Washington, M.K.3    DuBois, R.N.4
  • 60
    • 84965187257 scopus 로고
    • The age distribution of cancer and a multi-stage theory of carcinogenesis
    • Armitage P, Doll R. The age distribution of cancer and a multi-stage theory of carcinogenesis. Br J Cancer 1954; 8:1-12.
    • (1954) Br J Cancer , vol.8 , pp. 1-12
    • Armitage, P.1    Doll, R.2
  • 61
    • 78651056338 scopus 로고
    • Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin
    • Slaughter DP, Southwick HW, Smejkal W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer 1953; 6:963-8.
    • (1953) Cancer , vol.6 , pp. 963-968
    • Slaughter, D.P.1    Southwick, H.W.2    Smejkal, W.3
  • 62
    • 0020529870 scopus 로고
    • Papillomas induced by initiation-promotion differ from those induced by carcinogen alone
    • Reddy AL, Fialkow PJ. Papillomas induced by initiation-promotion differ from those induced by carcinogen alone. Nature 1983; 304:69-71.
    • (1983) Nature , vol.304 , pp. 69-71
    • Reddy, A.L.1    Fialkow, P.J.2
  • 63
    • 0035153878 scopus 로고    scopus 로고
    • Presence of genetic alterations in microdissected stroma of human colon and breast cancers
    • Wernert N, Locherbach C, Wellmann A, Behrens P, Hugel A. Presence of genetic alterations in microdissected stroma of human colon and breast cancers. Anticancer Research 2001; 21:2259-64.
    • (2001) Anticancer Research , vol.21 , pp. 2259-2264
    • Wernert, N.1    Locherbach, C.2    Wellmann, A.3    Behrens, P.4    Hugel, A.5
  • 64
    • 0024396203 scopus 로고
    • The receptor for epidermal growth factor is present in human fetal kidney, liver and lung
    • Nexo E, Kryger-Baggesen N. The receptor for epidermal growth factor is present in human fetal kidney, liver and lung. Regul Pept 1989; 26:1-8.
    • (1989) Regul Pept , vol.26 , pp. 1-8
    • Nexo, E.1    Kryger-Baggesen, N.2
  • 65
    • 20444421216 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-targeted treatment for advanced colorectal carcinoma
    • Venook AP. Epidermal growth factor receptor-targeted treatment for advanced colorectal carcinoma. Cancer 2005; 103:2435-46.
    • (2005) Cancer , vol.103 , pp. 2435-2446
    • Venook, A.P.1


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