Counting human somatic cell replications: Methylation mirrors endometrial stem cell divisions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 49, 2005, Pages 17739-17744

  Kim, Jung Yeon ^a,d   Tavaré, Simon ^b,c   Shibata, Darryl ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d Inje University College of Medicine   (South Korea)

Author keywords

Cancer; Endometrium; Molecular clock

Indexed keywords

ESTROGEN;

AGE; AGING; ARTICLE; CANCER; CELL DIVISION; CELL PROLIFERATION; CELL SURVIVAL; ENDOMETRIUM; EPIGENETICS; ERROR; FEMALE; HUMAN; HUMAN TISSUE; LIFESPAN; MENOPAUSE AND CLIMACTERIUM; MENSTRUAL CYCLE; METHYLATION; MOLECULAR CLOCK; MULTIPARA; PRIORITY JOURNAL; SOMATIC CELL; STEM CELL; UTERUS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; CELL COUNT; CELL DIVISION; DNA; DNA METHYLATION; ENDOMETRIUM; FEMALE; HUMANS; MIDDLE AGED; OBESITY; STEM CELLS;

EID: 29144521716     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0503976102     Document Type: Article

References (17)

1. Pike, M. C., Pearce, C. L. & Wu, A. H. (2004) Oncogene 23, 6379-6391.
2. Spradling, A., Drummond-Barbosa, D. & Kai, T. (2001) Nature 414, 98-104.
3. Padykula, H. A. (1991) Ann. N.Y. Acad. Sci. 622, 47-56.
4. Gargett, C. E. (2004) Aust. N. Z. J. Obstet. Gynaecol. 44, 380-386.
5. Kondo, M., Wagers, A. J., Manz, M. G., Prohaska, S. S., Scherer, D. C., Beilhack, G. F., Shizuru, J. A. & Weissman, I. L. (2003) Annu. Rev. Immunol. 21, 759-806.
6. Potten, C. S. & Loeffler, M. (1990) Development (Cambridge, U.K.) 110, 1001-1020.
7. Bromham, L. & Penny, D. (2003) Nat. Rev. Genet. 4, 216-224.
8. Ahuja, N., Li, Q., Mohan, A. L., Baylin, S. B. & Issa, J. P. (1998) Cancer Res. 58, 5489-5494.
9. Yatabe, Y., Tavaré, S. & Shibata D. (2001) Proc. Natl. Acad. Sci. USA 98, 10839-10844.
10. Potten, C. S., Kellet, M., Rew, D. A. & Roberts, S. A. (1992) Gut 33, 524-529.
11. Bird, A. (2002) Genes Dev. 16, 6-21.
12. Tanaka, M., Kyo, S., Kanaya, T., Yatabe, N., Nakamura, M., Maida, Y., Okabe, M. & Inoue, M. (2003) Am. J. Pathol. 163, 295-301.
13. Key, T. J. & Pike, M. C. (1988) Br. J. Cancer 57, 205-212.
14. Preston-Martin, S., Pike, M. C., Ross, R. K. Jones, P. A. & Henderson, B. E. (1990) Cancer Res. 50, 7415-7421.
15. Watt, F. M. & Hogan, B. L. (2000) Science 287, 1427-1430.
16. Chan, R. W., Schwab, K. E. & Gargett, C. E. (2004) Biol. Reprod. 70, 1738-1750.
17. Jemal, A., Murray, T., Ward, E., Samuels, A., Tiwari, R. C., Ghafoor, A., Feuer, E. J. & Thun, M. J. (2005) CA Cancer J. Clin. 55, 10-30.